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Results for “HLA-A*02:01-positive”

17 trials

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Showing 17 of 17 results

Early research (Phase 1)UnknownNCT04318964
What this trial is testing

TAEST16001 in the Treatment of Soft Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma
Sun Yat-sen University 12
Early research (Phase 1)Looking for participantsNCT07613723
What this trial is testing

Test the Safety, Tolerability and Effect of ZI-MA4-1 for Patients With Locally Advanced or Metastatic Solid Malignancies

Who this might be right for
Ovarian CancerSquamous Non-Small Cell Lung Cancer (NSCLC)Synovial Sarcomas+1 more
Zelluna Immunotherapy AS 9
Early research (Phase 1)WithdrawnNCT05867056
What this trial is testing

Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection

Who this might be right for
Hepatitis B, Chronic
Immunocore Ltd
Early research (Phase 1)Looking for participantsNCT07156136
What this trial is testing

Study of IMC-P115C in Advanced PRAME-Positive Cancers

Who this might be right for
PRAME PositiveCancerHLA-A*02:01-positive
Immunocore Ltd 140
Early research (Phase 1)Not Yet RecruitingNCT07583316
What this trial is testing

First-in-Human Study of CRPA1A2, a MAGE-A1/HLA-A*02:01 Bispecific T-Cell Engager, in Patients With Solid Tumors

Who this might be right for
Lung Cancer (Locally Advanced or Metastatic)Esophagus CancerHead and Neck Cancer+1 more
Corregene Biotechnology Co., Ltd 192
Large-scale testing (Phase 3)Looking for participantsNCT06112314
What this trial is testing

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

Who this might be right for
Advanced Melanoma
Immunocore Ltd 680
Large-scale testing (Phase 3)Looking for participantsNCT06246149
What this trial is testing

Adjuvant Tebentafusp in High Risk Ocular Melanoma

Who this might be right for
Uveal Melanoma
European Organisation for Research and Treatment of Cancer - EORTC 290
Testing effectiveness (Phase 2)Study completedNCT02960230
What this trial is testing

H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaGliomaDiffuse Midline Glioma, H3 K27M-Mutant
Sabine Mueller, MD, PhD 50
Testing effectiveness (Phase 2)Looking for participantsNCT06424340
What this trial is testing

MB-dNPM1-TCR.1 in Relapsed/Refractory AML

Who this might be right for
Leukemia, Myeloid, Acute
Miltenyi Biomedicine GmbH 29
Not applicableAvailableNCT04960891
What this trial is testing

A Cohort IND Expanded Access Program for Supporting Patient Access to Tebentafusp

Who this might be right for
Uveal Melanoma
Immunocore Ltd
Testing effectiveness (Phase 2)Ended earlyNCT05549921
What this trial is testing

Phase II Study of TAEST16001 in Soft Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma
Sun Yat-sen University 8
Early research (Phase 1)Not Yet RecruitingNCT06358053
What this trial is testing

CRTE7A2-01 TCR-T Cells for HPV-16 Positive Advanced Cancers

Who this might be right for
Cervical CancerAnal CancerHead and Neck Cancers+1 more
Corregene Biotechnology Co., Ltd 24
Large-scale testing (Phase 3)Looking for participantsNCT05549297
What this trial is testing

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

Who this might be right for
Advanced Melanoma
Immunocore Ltd 540
Early research (Phase 1)Looking for participantsNCT05877599
What this trial is testing

NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Who this might be right for
Non-small Cell Lung CancerHead and Neck Squamous Cell CarcinomaColorectal Carcinoma+5 more
AstraZeneca 45
Early research (Phase 1)Not Yet RecruitingNCT07493122
What this trial is testing

Study of IMC-S118AI in Type 1 Diabetes

Who this might be right for
Type 1 DiabetesType 1 Diabetes (T1D)Diabetes Type 1
Immunocore Ltd 154
Testing effectiveness (Phase 2)Looking for participantsNCT06942442
What this trial is testing

A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma

Who this might be right for
HLA-A*0201 Positive Cells PresentClear Cell Sarcoma (CCS)
Sarcoma Alliance for Research through Collaboration 47
Testing effectiveness (Phase 2)Looking for participantsNCT06840119
What this trial is testing

Phase 1/2 Study of IMC-R117C in Selected Advanced Cancers

Who this might be right for
CancerHLA-A*02:01-positive
Immunocore Ltd 600