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Results for “HPV 16+ Recurrent or Metastatic Cancer”

21 trials

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Showing 20 of 21 results

Testing effectiveness (Phase 2)Study completedNCT04260126
What this trial is testing

Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC

Who this might be right for
Metastatic Head and Neck CancerRecurrent Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
PDS Biotechnology Corp. 95
Early research (Phase 1)Study completedNCT00019110
What this trial is testing

Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer

Who this might be right for
Anal CancerCervical CancerEsophageal Cancer+3 more
National Cancer Institute (NCI)
Large-scale testing (Phase 3)Active Not RecruitingNCT04534205
What this trial is testing

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

Who this might be right for
Unresectable Head and Neck Squamous Cell CarcinomaMetastatic Head and Neck CancerRecurrent Head and Neck Cancer
BioNTech SE 358
Testing effectiveness (Phase 2)Active Not RecruitingNCT05280457
What this trial is testing

HPV 16-positive and/or HPV 18-positive Recurrent and/or For Patients With Metastatic Head and Neck Cancer to Evaluate GX-188E DNA Vaccination, GX-I7 and Nivolumab Combination Therapy

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Yonsei University 21
Early research (Phase 1)Study completedNCT04084951
What this trial is testing

Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Adult Solid Tumor
SQZ Biotechnologies 30
Early research (Phase 1)Ended earlyNCT04892043
What this trial is testing

Study of SQZ-AAC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Adult Solid Tumor
SQZ Biotechnologies 5
Testing effectiveness (Phase 2)Looking for participantsNCT06797986
What this trial is testing

A Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects With HPV Positive HNSCC.

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)HPV (Human Papillomavirus)-Associated CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Cellid Co., Ltd. 37
Early research (Phase 1)UnknownNCT05895370
What this trial is testing

HPV-T in HPV-16 Positive Recurrent or Metastatic Solid Tumors

Who this might be right for
Solid Tumor
BGI, China 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT04713046
What this trial is testing

Safety and Efficacy of Allogeneic HPV-specific T Cells in Adults With Recurrent or Metastatic HPV16+ Cancers

Who this might be right for
HPV 16+ Recurrent or Metastatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 24
Testing effectiveness (Phase 2)Study completedNCT04405349
What this trial is testing

Investigating the Combination of VB10.16 and Atezolizumab in Patients With HPV 16-positive Cervical Cancer

Who this might be right for
Cervical CancerCervix Cancer
Nykode Therapeutics ASA 52
Testing effectiveness (Phase 2)Ended earlyNCT05357898
What this trial is testing

Study of SQZ-eAPC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Adult Solid Tumor
SQZ Biotechnologies 20
Early research (Phase 1)Looking for participantsNCT07081984
What this trial is testing

Study of TI-0093 Injection With Recurrent/Metastatic HPV-16 Positive Solid Tumors

Who this might be right for
HPV 16+ Recurrent or Metastatic CancerHNSCCCervical Cancer
Therorna 12
Large-scale testing (Phase 3)WithdrawnNCT06513884
What this trial is testing

HB-202/HB-201 With Pembrolizumab in Patients With HPV16+ Recurrent/Metastatic Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma Recurrent
Hookipa Biotech GmbH
Testing effectiveness (Phase 2)Ended earlyNCT03439085
What this trial is testing

DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers

Who this might be right for
Human Papillomavirus-16 PositiveHuman Papillomavirus-18 PositiveMetastatic Malignant Neoplasm+18 more
M.D. Anderson Cancer Center 41
Testing effectiveness (Phase 2)Study completedNCT02866006
What this trial is testing

Safety and Tolerability Evaluation Study of BVAC-C in Patients With HPV Type 16 or 18 Positive Cervical Cancer

Who this might be right for
Uterine Cervical Neoplasms
Cellid Co., Ltd. 32
Testing effectiveness (Phase 2)Looking for participantsNCT06016920
What this trial is testing

Safety and Efficacy of VB10.16 and Pembrolizumab in Patients With Head-Neck Squamous Cell Carcinoma

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell CarcinomaHNSCC
Nykode Therapeutics ASA 110
Large-scale testing (Phase 3)Ended earlyNCT06790966
What this trial is testing

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent Head and Neck CancerMetastatic Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
PDS Biotechnology Corp. 12
Testing effectiveness (Phase 2)WithdrawnNCT06099418
What this trial is testing

Efficacy and Safety of VB10.16 Alone or in Combination With Atezolizumab in Patients With Advanced Cervical Cancer.

Who this might be right for
HPV-Related Cervical CarcinomaHPV-Related MalignancyCervical Cancer
Nykode Therapeutics ASA
Early research (Phase 1)Study completedNCT03978689
What this trial is testing

Study in Patients With HPV16+ Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell CarcinomaHPV-Related Carcinoma
Cue Biopharma 80
Early research (Phase 1)Not Yet RecruitingNCT05582590
What this trial is testing

Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal Cancers

Who this might be right for
Oropharyngeal CancerHuman Papilloma VirusHead and Neck Cancer+8 more
NexImmune Inc. 36
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