Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “HPV Positive Oropharyngeal Squamous Cell Carcinoma”

116 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 116 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04862650
What this trial is testing

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+22 more
Marcelo Bonomi 46
Very early researchLooking for participantsNCT06914999
What this trial is testing

Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+13 more
Emory University
Testing effectiveness (Phase 2)Looking for participantsNCT06088381
What this trial is testing

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

Who this might be right for
Head and Neck CancerHead and Neck Squamous Cell CarcinomaOropharynx Cancer+2 more
University of Maryland, Baltimore 61
Early research (Phase 1)Active Not RecruitingNCT04533750
What this trial is testing

Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaAdvanced Hypopharyngeal Squamous Cell CarcinomaAdvanced Laryngeal Squamous Cell Carcinoma+15 more
National Cancer Institute (NCI) 21
Early research (Phase 1)Study completedNCT02113878
What this trial is testing

Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

Who this might be right for
Carcinoma, Squamous Cell of Head and NeckHPV Positive Oropharyngeal Squamous Cell CarcinomaHypopharyngeal Cancer+3 more
Dana-Farber Cancer Institute 23
Not applicableLooking for participantsNCT06307015
What this trial is testing

De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE)

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Royal North Shore Hospital 25
Testing effectiveness (Phase 2)Study completedNCT04260126
What this trial is testing

Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC

Who this might be right for
Metastatic Head and Neck CancerRecurrent Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
PDS Biotechnology Corp. 95
Testing effectiveness (Phase 2)WithdrawnNCT02298595
What this trial is testing

Cetuximab, Cisplatin and BYL719 for HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Carcinoma, SquamousSquamous Cell CarcinomaOropharyngeal Neoplasms+1 more
Julie E. Bauman, MD, MPH
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06505551
What this trial is testing

Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma

Who this might be right for
HPV-Related Squamous Cell CarcinomaHPV-Related Cervical Squamous Cell CarcinomaHPV-Related Vulvar Squamous Cell Carcinoma+4 more
SCG Cell Therapy Pte. Ltd. 66
Not applicableWithdrawnNCT04140513
What this trial is testing

Digital PET Scan for the Prediction of Outcomes in Patients With Locally Advanced Oropharyngeal Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Oropharyngeal Squamous Cell Carcinoma+5 more
Ohio State University Comprehensive Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT02706691
What this trial is testing

BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck Cancer

Who this might be right for
FGFR Gene AmplificationFGFR1 Gene AmplificationFGFR2 Gene Amplification+7 more
University of Chicago 1
Early research (Phase 1)Study completedNCT02178072
What this trial is testing

Window Trial 5-aza in HNSCC, T-tare

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Yale University 18
Testing effectiveness (Phase 2)Looking for participantsNCT07063212
What this trial is testing

Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)

Who this might be right for
Squamous Cell Carcinoma of Head and NeckSinus CancerNasal Cavity Cancer+9 more
Memorial Sloan Kettering Cancer Center 40
Testing effectiveness (Phase 2)Looking for participantsNCT07497607
What this trial is testing

Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Sara Medek 31
Early research (Phase 1)WithdrawnNCT03575234
What this trial is testing

Nivolumab & IRX-2 With Surgery for Resectable Stage III-IVA Oral Cavity Cancer or HPV-Positive Oropharyngeal Cancer

Who this might be right for
Human Papillomavirus Positive Oropharyngeal Squamous Cell CarcinomaStage II Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7+2 more
Emory University
Not applicableNot Yet RecruitingNCT07797738
What this trial is testing

Prognostic Biomarkers for Patients With Human Papillomavirus (HPV) Positive Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma (OPSCC)HPVHPV Positive Oropharyngeal Squamous Cell Carcinoma
Abramson Cancer Center at Penn Medicine 30
Large-scale testing (Phase 3)Study completedNCT03258554
What this trial is testing

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Head and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell Carcinoma+17 more
National Cancer Institute (NCI) 196
Testing effectiveness (Phase 2)Study completedNCT02002182
What this trial is testing

ADXS 11-001 Vaccination Prior to Robotic Surgery, HPV-Positive Oropharyngeal Cancer

Who this might be right for
Head and Neck CancerSquamous Cell Carcinoma of the Head and NeckHPV Positive Oropharyngeal Squamous Cell Carcinoma
Andrew Sikora 15
Early research (Phase 1)Looking for participantsNCT06868433
What this trial is testing

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
Emory University
Large-scale testing (Phase 3)Active Not RecruitingNCT03952585
What this trial is testing

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Who this might be right for
Basaloid Squamous Cell CarcinomaClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+5 more
National Cancer Institute (NCI)
Next Page
20
40
384