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Results for “HPV Positive Oropharyngeal Squamous Cell Carcinoma”

108 trials

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Showing 20 of 108 results

Large-scale testing (Phase 3)Active Not RecruitingNCT03952585
What this trial is testing

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Who this might be right for
Basaloid Squamous Cell CarcinomaClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+5 more
National Cancer Institute (NCI) 384
Large-scale testing (Phase 3)UnknownNCT01855451
What this trial is testing

Weekly Cetuximab/RT Versus Weekly Cisplatin/RT in HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Trans Tasman Radiation Oncology Group 189
Early research (Phase 1)Looking for participantsNCT06868433
What this trial is testing

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
Emory University
Testing effectiveness (Phase 2)WithdrawnNCT02298595
What this trial is testing

Cetuximab, Cisplatin and BYL719 for HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Carcinoma, SquamousSquamous Cell CarcinomaOropharyngeal Neoplasms+1 more
Julie E. Bauman, MD, MPH
Not applicableActive Not RecruitingNCT05119036
What this trial is testing

Adjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell Carcinoma

Who this might be right for
Squamous Cell Carcinoma of the OropharynxHPV Positive Oropharyngeal Squamous Cell Carcinoma
Indiana University 83
Early research (Phase 1)Looking for participantsNCT06747390
What this trial is testing

Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma (OPSCCA)Oropharyngeal CancerHuman Papilloma Virus+1 more
Ryan Carey 30
Early research (Phase 1)Active Not RecruitingNCT04533750
What this trial is testing

Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaAdvanced Hypopharyngeal Squamous Cell CarcinomaAdvanced Laryngeal Squamous Cell Carcinoma+15 more
National Cancer Institute (NCI) 21
Testing effectiveness (Phase 2)Ended earlyNCT02225496
What this trial is testing

Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Cancer
M.D. Anderson Cancer Center 1
Testing effectiveness (Phase 2)WithdrawnNCT04001413
What this trial is testing

Therapy for High-Risk HPV 16-Positive Oropharynx Cancer Patients

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell CarcinomaOropharynx CancerHPV-Related Carcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Large-scale testing (Phase 3)Temporarily pausedNCT05050162
What this trial is testing

Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaAdvanced Hypopharyngeal Squamous Cell CarcinomaAdvanced Laryngeal Squamous Cell Carcinoma+7 more
NRG Oncology 1,714
Testing effectiveness (Phase 2)Study completedNCT02048020
What this trial is testing

Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer

Who this might be right for
Human Papilloma Virus InfectionStage III Squamous Cell Carcinoma of the HypopharynxStage III Squamous Cell Carcinoma of the Larynx+13 more
Jonsson Comprehensive Cancer Center 26
Testing effectiveness (Phase 2)Looking for participantsNCT06016920
What this trial is testing

Safety and Efficacy of VB10.16 and Pembrolizumab in Patients with Head-Neck Squamous Cell Carcinoma

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell CarcinomaHNSCC
Nykode Therapeutics ASA 51
Not applicableStudy completedNCT01663259
What this trial is testing

Reduced-intensity Therapy for Oropharyngeal Cancer in Non-smoking HPV-16 Positive Patients

Who this might be right for
Squamous Cell Carcinoma of the OropharynxHPV
University of Michigan Rogel Cancer Center 43
Large-scale testing (Phase 3)Active Not RecruitingNCT06790966
What this trial is testing

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent Head and Neck CancerMetastatic Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
PDS Biotechnology Corp. 351
Not applicableLooking for participantsNCT03875716
What this trial is testing

Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Head and Neck Cancer
Dana-Farber Cancer Institute 111
Testing effectiveness (Phase 2)Active Not RecruitingNCT05714657
What this trial is testing

Shortened Course Adjuvant Radiotherapy Following TORS

Who this might be right for
HPV-Associated Oropharyngeal Squamous Cell Carcinoma
Abramson Cancer Center at Penn Medicine 104
Not applicableWithdrawnNCT03611205
What this trial is testing

Interim Digital PET/CT in Predicting Outcomes for Participants With Locally Advanced Oropharyngeal Cancer Undergoing Chemoradiation Therapy

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Ohio State University Comprehensive Cancer Center
Not applicableEnded earlyNCT05061940
What this trial is testing

This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.

Who this might be right for
Head and Neck CancerMelanomaHPV-Related Malignancy+5 more
Repertoire Immune Medicines 22
Testing effectiveness (Phase 2)Ended earlyNCT04106362
What this trial is testing

Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With HPV Positive, KRAS-Variant Stage III-IV Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8KRAS Protein Variant+2 more
Jonsson Comprehensive Cancer Center 1
Testing effectiveness (Phase 2)Looking for participantsNCT05108870
What this trial is testing

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

Who this might be right for
Human Papilloma VirusHPVHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
University of Chicago 98
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