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Results for “HPV-Associated Oropharyngeal Squamous Cell Carcinoma”

49 trials

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Showing 20 of 49 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06223568
What this trial is testing

Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer

Who this might be right for
Squamous Cell Carcinoma of the Head and NeckOropharynxHuman Papillomavirus Viruses+2 more
National Cancer Institute (NCI) 70
Not applicableStudy completedNCT06730412
What this trial is testing

CtDNA Liquid Biopsy for Early Assessment of Residual Disease in HPV-associated Head and Neck Cancer (Clear-HPVca)

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Massachusetts Eye and Ear Infirmary 103
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Testing effectiveness (Phase 2)Looking for participantsNCT04900623
What this trial is testing

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

Who this might be right for
HPV-Associated Oropharyngeal Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell CarcinomaHPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage+9 more
Jonathan Schoenfeld, MD, MPH 145
Large-scale testing (Phase 3)Study completedNCT01302834
What this trial is testing

Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer

Who this might be right for
Head and Neck CancerPrecancerous Condition
Radiation Therapy Oncology Group 987
Testing effectiveness (Phase 2)Looking for participantsNCT05307939
What this trial is testing

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

Who this might be right for
HPVOropharynx CancerHPV-Related Carcinoma+2 more
Memorial Sloan Kettering Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT06319963
What this trial is testing

Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

Who this might be right for
HPV-Related Cervical CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Theravectys S.A. 72
Early research (Phase 1)Looking for participantsNCT06589609
What this trial is testing

Phase 1 Clinical Trial of FluBHPVE6E7 Immunotherapy for HPV16-Associated Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma (SCC)
BlueSky Immunotherapies GmbH 12
Not applicableLooking for participantsNCT03875716
What this trial is testing

Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Head and Neck Cancer
Dana-Farber Cancer Institute 111
Not applicableLooking for participantsNCT04564989
What this trial is testing

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaCarcinoma, Squamous CellHead and Neck Squamous Cell Carcinoma+1 more
UNC Lineberger Comprehensive Cancer Center 220
Testing effectiveness (Phase 2)Study completedNCT01932697
What this trial is testing

Radiation Therapy and Docetaxel in Treating Patients With HPV-Related Oropharyngeal Cancer

Who this might be right for
Human Papillomavirus InfectionStage I Oropharyngeal Squamous Cell CarcinomaStage II Oropharyngeal Squamous Cell Carcinoma+3 more
Mayo Clinic 81
Testing effectiveness (Phase 2)Looking for participantsNCT06323460
What this trial is testing

Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Oropharyngeal Squamous Cell Carcinoma
Ohio State University Comprehensive Cancer Center 45
Not applicableLooking for participantsNCT06821243
What this trial is testing

Patients With Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention

Who this might be right for
Squamous Cell Carcinoma of Oropharynx
Regina Elena Cancer Institute 40
Not applicableEnded earlyNCT05061940
What this trial is testing

This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.

Who this might be right for
Head and Neck CancerMelanomaHPV-Related Malignancy+5 more
Repertoire Immune Medicines 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT05996523
What this trial is testing

Phase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 With Pembrolizumab Before Standard Treatment in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma (SCC)
National Cancer Institute (NCI) 26
Testing effectiveness (Phase 2)Study completedNCT02048020
What this trial is testing

Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer

Who this might be right for
Human Papilloma Virus InfectionStage III Squamous Cell Carcinoma of the HypopharynxStage III Squamous Cell Carcinoma of the Larynx+13 more
Jonsson Comprehensive Cancer Center 26
Testing effectiveness (Phase 2)Study completedNCT01084083
What this trial is testing

Induction Chemotherapy Followed By Cetuximab and Radiation in HPV-Associated Resectable Stage III/IV Oropharynx Cancer

Who this might be right for
Head and Neck CancerPrecancerous Condition
Eastern Cooperative Oncology Group 90
Not applicableEnded earlyNCT01891695
What this trial is testing

OPSCC N0 Nodal Control With Reduced IMRT

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma (OPSCCA)HPV (Human Papillomavirus)-Associated
Paul W. Read, MD 1
Large-scale testing (Phase 3)UnknownNCT01855451
What this trial is testing

Weekly Cetuximab/RT Versus Weekly Cisplatin/RT in HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Trans Tasman Radiation Oncology Group 189
Not applicableStudy completedNCT00897988
What this trial is testing

DNA Analysis of Tumor Tissue Samples From Patients With Human Papilloma Virus-Associated Cancer of the Oropharynx

Who this might be right for
Head and Neck Cancer
Vanderbilt University Medical Center 40
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