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Results for “HPV-Positive Oropharyngeal Squamous Cell Carcinoma”

115 trials

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Showing 20 of 115 results

Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI) 150
Not applicableLooking for participantsNCT06356272
What this trial is testing

Oropharynx (OPX) Biomarker Trial

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Oropharyngeal Squamous Cell Carcinoma+8 more
Mayo Clinic 560
Testing effectiveness (Phase 2)Study completedNCT03342911
What this trial is testing

Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery

Who this might be right for
Name Human Papillomavirus Positive Oropharyngeal Squamous Cell CarcinomaStage II Oropharyngeal Squamous Cell CarcinomaStage III Hypopharyngeal Squamous Cell Carcinoma+19 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 34
Testing effectiveness (Phase 2)Looking for participantsNCT05419089
What this trial is testing

The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)

Who this might be right for
HPV-positive Oropharyngeal Squamous Cell Carcinoma
Icahn School of Medicine at Mount Sinai 83
Testing effectiveness (Phase 2)Active Not RecruitingNCT04502407
What this trial is testing

Trial of De-Intensified Post-operative Chemoradiation Following Robotic Surgery for HPV-positive Oropharyngeal Cancer

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Cedars-Sinai Medical Center 40
Early research (Phase 1)Study completedNCT02178072
What this trial is testing

Window Trial 5-aza in HNSCC, T-tare

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Yale University 18
Not applicableLooking for participantsNCT03396718
What this trial is testing

De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell Carcinomas

Who this might be right for
Head-and-neck Squamous Cell Carcinoma
Technische Universität Dresden 304
Testing effectiveness (Phase 2)Looking for participantsNCT04444869
What this trial is testing

Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer

Who this might be right for
Cancer of the Head and NeckOropharynx CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
University of Missouri-Columbia 28
Testing effectiveness (Phase 2)Active Not RecruitingNCT03224000
What this trial is testing

Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer

Who this might be right for
Malignant Neoplasms of Lip Oral Cavity and PharynxOropharyngeal Cancer
M.D. Anderson Cancer Center 90
Not applicableActive Not RecruitingNCT05814549
What this trial is testing

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

Who this might be right for
Oropharyngeal CancerHPV-Related CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Memorial Sloan Kettering Cancer Center 9
Large-scale testing (Phase 3)UnknownNCT01855451
What this trial is testing

Weekly Cetuximab/RT Versus Weekly Cisplatin/RT in HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Trans Tasman Radiation Oncology Group 189
Not applicableLooking for participantsNCT06115772
What this trial is testing

Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study

Who this might be right for
Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma
Mayo Clinic 154
Testing effectiveness (Phase 2)Ended earlyNCT03799445
What this trial is testing

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma+8 more
M.D. Anderson Cancer Center
Not applicableLooking for participantsNCT05649865
What this trial is testing

Monitoring and Early Response Evaluation Using HPV DNA - A Study on Patients With HPV-positive Throat Cancer (MER-HPV)

Who this might be right for
Oropharynx Squamous Cell Carcinoma
Region Skane 150
Early research (Phase 1)Active Not RecruitingNCT04533750
What this trial is testing

Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaAdvanced Hypopharyngeal Squamous Cell CarcinomaAdvanced Laryngeal Squamous Cell Carcinoma+15 more
National Cancer Institute (NCI) 21
Testing effectiveness (Phase 2)Looking for participantsNCT06088381
What this trial is testing

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

Who this might be right for
Head and Neck CancerHead and Neck Squamous Cell CarcinomaOropharynx Cancer+2 more
University of Maryland, Baltimore 61
Large-scale testing (Phase 3)Active Not RecruitingNCT05721755
What this trial is testing

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+8 more
ECOG-ACRIN Cancer Research Group
Testing effectiveness (Phase 2)Study completedNCT04180215
What this trial is testing

A Phase 1/2 Study in Patients With HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Other Cancers

Who this might be right for
HPV-Related Squamous Cell Carcinoma
Hookipa Biotech GmbH 198
Not applicableStudy completedNCT05524025
What this trial is testing

The SPOT-HPV Study

Who this might be right for
HPV InfectionHPV Positive Oropharyngeal Squamous Cell Carcinoma
Dana-Farber Cancer Institute 360
Not applicableStudy completedNCT04871490
What this trial is testing

Improving Detection and Early Action for HPV-positive Oropharynx Cancer

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Brigham and Women's Hospital 40
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