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Results for “HPV-positive Oropharyngeal Squamous Cell Carcinoma”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT03258008
What this trial is testing

Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer

Who this might be right for
Malignant Neoplasms of Ill-defined Secondary and Unspecified SitesMalignant Neoplasms of Lip Oral Cavity and PharynxOropharyngeal Cancer
M.D. Anderson Cancer Center 3
Not applicableLooking for participantsNCT06356272
What this trial is testing

Oropharynx (OPX) Biomarker Trial

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Oropharyngeal Squamous Cell Carcinoma+8 more
Mayo Clinic 560
Not applicableLooking for participantsNCT06307015
What this trial is testing

De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE)

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Royal North Shore Hospital 25
Not applicableLooking for participantsNCT03396718
What this trial is testing

De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell Carcinomas

Who this might be right for
Head-and-neck Squamous Cell Carcinoma
Technische Universität Dresden 304
Not applicableWithdrawnNCT03611205
What this trial is testing

Interim Digital PET/CT in Predicting Outcomes for Participants With Locally Advanced Oropharyngeal Cancer Undergoing Chemoradiation Therapy

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Ohio State University Comprehensive Cancer Center
Not applicableWithdrawnNCT04140513
What this trial is testing

Digital PET Scan for the Prediction of Outcomes in Patients With Locally Advanced Oropharyngeal Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Oropharyngeal Squamous Cell Carcinoma+5 more
Ohio State University Comprehensive Cancer Center
Testing effectiveness (Phase 2)Study completedNCT04541355
What this trial is testing

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Who this might be right for
Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Head and Neck Squamous Cell Carcinoma+26 more
Hyunseok Kang, MD
Testing effectiveness (Phase 2)Ended earlyNCT02225496
What this trial is testing

Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Cancer
M.D. Anderson Cancer Center 1
Large-scale testing (Phase 3)Ended earlyNCT06790966
What this trial is testing

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent Head and Neck CancerMetastatic Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
PDS Biotechnology Corp. 12
Testing effectiveness (Phase 2)Looking for participantsNCT05686226
What this trial is testing

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

Who this might be right for
Cervical CancerThroat CancerOropharynx Cancer+18 more
Christian Hinrichs 20
Early research (Phase 1)Active Not RecruitingNCT04533750
What this trial is testing

Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaAdvanced Hypopharyngeal Squamous Cell CarcinomaAdvanced Laryngeal Squamous Cell Carcinoma+15 more
National Cancer Institute (NCI) 21
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06759155
What this trial is testing

Phase II Clinical Trial of De-Intensified Therapy in Human Papilloma Virus (HPV) Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
OPSCCOropharyngeal Squamous Cell Carcinoma (SCC)HPV Associated Cancers
University of Vermont Medical Center 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT03410615
What this trial is testing

Cisplatin + Radiotherapy vs Durvalumab + Radiotherapy Followed by Durvalumab vs Durvalumab + Radiotherapy Followed by Tremelimumab + Durvalumab in Intermediate-Risk HPV-Positive Oropharyngeal SCC

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
Canadian Cancer Trials Group 129
Not applicableStudy completedNCT01984359
What this trial is testing

HPV Serum DNA Levels Predicting Outcome in p16+ Squamous Cell Head and Neck Cancer

Who this might be right for
Subjects With p16 Positive/HPV Positive Squamous Cell Carcinomas of the Oropharynx
Abramson Cancer Center at Penn Medicine 80
Not applicableLooking for participantsNCT06662058
What this trial is testing

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Cutaneous Squamous Cell Carcinoma of the Head and NeckHead and Neck Carcinoma of Unknown Primary+30 more
Emory University 118
Testing effectiveness (Phase 2)Looking for participantsNCT06532279
What this trial is testing

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+38 more
NRG Oncology
Large-scale testing (Phase 3)Active Not RecruitingNCT05063552
What this trial is testing

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07628062
What this trial is testing

Phase 2 Study of NAI, HPV Vaccine, and Nab-Paclitaxel in HPV-Positive Oropharyngeal Cancer Followed by De-Intensified Radiation Compared With Standard Chemoradiation

Who this might be right for
HPV-Positive Oropharyngeal Squamous Cell CarcinomaOropharyngeal Squamous Cell CarcinomaHead and Neck Cancer
ImmunityBio, Inc. 70
Early research (Phase 1)Study completedNCT03978689
What this trial is testing

Study in Patients With HPV16+ Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell CarcinomaHPV-Related Carcinoma
Cue Biopharma 80
Testing effectiveness (Phase 2)Study completedNCT04260126
What this trial is testing

Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC

Who this might be right for
Metastatic Head and Neck CancerRecurrent Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
PDS Biotechnology Corp. 95
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