Not applicableStudy completedNCT04749810What this trial is testingObservational Study of Elizaria® in aHUS PatientsWho this might be right forAtypical Hemolytic Uremic SyndromeaHUS AO GENERIUM 50
Testing effectiveness (Phase 2)Study completedNCT03518203What this trial is testingEculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant RecipientsWho this might be right forThrombotic MicroangiopathiesAtypical Hemolytic Uremic SyndromeMultiple Organ Dysfunction Syndrome Children's Hospital Medical Center, Cincinnati 23
Not applicableAvailableNCT02355782What this trial is testingOMS721 Compassionate Use in Patients With Thrombotic MicroangiopathyWho this might be right forThrombotic Microangiopathy Michal Nowicki
Not applicableStudy completedNCT01770951What this trial is testingA Retrospective, Observational, Non-interventional Trial to Assess Eculizumab Treatment Effect in Patients With Atypical Hemolytic Uremic Syndrome (aHUS)Who this might be right forAtypical Hemolytic Uremic Syndrome (aHUS) Alexion Pharmaceuticals, Inc. 30
Not applicableLooking for participantsNCT04745195What this trial is testingComplement Prospective Evaluation of Thrombotic Microangiopathy on EndotheliumWho this might be right forThrombotic MicroangiopathiesHemolytic Uremic Syndrome, AtypicalHemolytic-Uremic Syndrome Maastricht University Medical Center 42
Large-scale testing (Phase 3)WithdrawnNCT01433003What this trial is testingThe Plasma Large-Volume Exchange RCTWho this might be right forPurpura, Thrombotic ThrombocytopenicHemolytic Uremic Syndrome London Health Sciences Centre
Not applicableStudy completedNCT00360685What this trial is testingTacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTXWho this might be right forMucositisGraft-versus-host Disease H. Lee Moffitt Cancer Center and Research Institute 89
Testing effectiveness (Phase 2)WithdrawnNCT03303313What this trial is testingAn Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic SyndromeWho this might be right forAtypical Hemolytic Uremic Syndrome Alnylam Pharmaceuticals
Not applicableLooking for participantsNCT01793168What this trial is testingRare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordWho this might be right forRare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more Sanford Health 20,000
Not applicableStudy completedNCT01755429What this trial is testingTo Characterize the Safety and Tolerability of Eculizumab in Two Japanese aHUS PatientsWho this might be right forATYPICAL HEMOLYTIC UREMIC SYNDROME (AHUS) Alexion Pharmaceuticals, Inc. 2
Not applicableUnknownNCT03574506What this trial is testingEculizumab Use in the Postpartum Period for the Treatment of Pregnancy Associated aHUS: A Case SeriesWho this might be right forAtypical Hemolytic Uremic SyndromePregnancy Fundación Grupo de Investigación en Cuidados Intensivos y Obstetricia 50
Not applicableUnknownNCT03580941What this trial is testingUsefulness of a Diagnostic Algorithm to Diagnose Thrombotic Microangiopathies in PregnancyWho this might be right forHemolytic-Uremic Syndrome Fundación Grupo de Investigación en Cuidados Intensivos y Obstetricia 75
Large-scale testing (Phase 3)Study completedNCT01410916What this trial is testingSafety and Efficacy Study of Eculizumab in Shiga-Toxin Producing Escherichia Coli Hemolytic-Uremic Syndrome (STEC-HUS)Who this might be right forShiga-like Toxin-producing Escherichia Coli Alexion Pharmaceuticals, Inc. 198
Testing effectiveness (Phase 2)Study completedNCT00844844What this trial is testingOpen Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUSWho this might be right forAtypical Hemolytic Uremic Syndrome Alexion Pharmaceuticals, Inc. 1
Large-scale testing (Phase 3)Study completedNCT05876351What this trial is testingEculizumab in Pediatric and Adult Participants With Atypical Hemolytic Uremic Syndrome (aHUS) in ChinaWho this might be right forAtypical Hemolytic Uremic Alexion Pharmaceuticals, Inc. 25
Large-scale testing (Phase 3)Study completedNCT02205541What this trial is testingEculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHUWho this might be right forHemolytic Uremic Syndrome of Childhood University Hospital, Toulouse 100
Post-approval studies (Phase 4)Study completedNCT02574403What this trial is testingStudy Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUSWho this might be right forAtypical Hemolytic Uremic Syndrome Nantes University Hospital 58
Testing effectiveness (Phase 2)Study completedNCT00844428What this trial is testingOpen Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUSWho this might be right forAtypical Hemolytic Uremic Syndrome Alexion Pharmaceuticals, Inc. 5
Not applicableStudy completedNCT01561248What this trial is testingStudy of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic ColitisWho this might be right forHemolytic Uremic SyndromeHemorrhagic ColitisIntestinal Infectious Disease+1 more Universitätsklinikum Hamburg-Eppendorf 33
Large-scale testing (Phase 3)Ended earlyNCT00004465What this trial is testingPhase III Randomized Study of SYNSORB Pk in Children With E. Coli-Associated Hemolytic Uremic SyndromeWho this might be right forHemolytic Uremic Syndrome National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 145