Not applicableLooking for participantsNCT07399730What this trial is testingRavulizumab Outcomes in Polish Patients With aHUSWho this might be right forAtypical Hemolytic Uremic Syndrome AstraZeneca 80
Not applicableStudy completedNCT02134171What this trial is testingEarly Predictive Factors of Cardiac and Cerebral Involvement in TMAWho this might be right forThrombotic MicroangiopathiesThrombotic Thrombocytopenic Purpura Assistance Publique - Hôpitaux de Paris 119
Not applicableStudy completedNCT07218536What this trial is testingThe Burden of Atypical Hemolytic Uremic Syndrome and The Clinical Characteristics of Patients in Egyptian Hospitals A Multicenter, Observational, Retrospective Cohort Study in EgyptWho this might be right forAtypical Hemolytic Uremic Syndrome AstraZeneca 200
Not applicableActive Not RecruitingNCT06099236What this trial is testingA Prospective, Non-interventional, Observational Study of Presentation, Treatment Patterns and Outcomes in Atypical Hemolytic Uremic Syndrome PatientsWho this might be right forAtypical Hemolytic Uremic Syndrome(aHUS) AstraZeneca 367
Testing effectiveness (Phase 2)Study completedNCT01193348What this trial is testingAn Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic SyndromeWho this might be right forAtypical Hemolytic-Uremic Syndrome Alexion Pharmaceuticals, Inc. 22
Large-scale testing (Phase 3)Active Not RecruitingNCT04958265What this trial is testingA Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)Who this might be right forAtypical Hemolytic Uremic Syndrome Hoffmann-La Roche 41
Testing effectiveness (Phase 2)Study completedNCT00838513What this trial is testingOpen Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS)Who this might be right forAtypical Hemolytic Uremic Syndrome Alexion Pharmaceuticals, Inc. 15
Large-scale testing (Phase 3)Looking for participantsNCT05935215What this trial is testingEfficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)Who this might be right forAtypical Hemolytic Uremic Syndrome Novartis Pharmaceuticals 50
Not applicableWithdrawnNCT02626663What this trial is testingThe Role of Microparticles as a BiomarkerWho this might be right forAtypical Hemolytic Uremic SyndromeThrombotic Thrombocytopenic PurpuraMicroparticles+1 more University of Rochester
Not applicableStudy completedNCT04777435What this trial is testingTherapeutic Orientation Test in Thrombotic MicroangiopathyWho this might be right forThrombotic Micro-angiopathy University Hospital, Montpellier 100
Not applicableLooking for participantsNCT05219110What this trial is testingHyperhydration in Children With Shiga Toxin-Producing E. Coli InfectionWho this might be right forShiga Toxin-Producing Escherichia Coli (E. Coli) InfectionHemolytic-Uremic Syndrome University of Calgary 1,040
Not applicableEnded earlyNCT02614898What this trial is testingEvaluation of Potential Predictors of Disease Progression in Participants With Atypical Hemolytic Uremic Syndrome (aHUS) Including Genetics, Biomarkers, and TreatmentWho this might be right forAtypical Hemolytic Uremic Syndrome Alexion Pharmaceuticals, Inc. 67
Large-scale testing (Phase 3)Study completedNCT04889430What this trial is testingEfficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor TherapyWho this might be right forAtypical Hemolytic Uremic Syndrome Novartis Pharmaceuticals 34
Testing effectiveness (Phase 2)Study completedNCT00844545What this trial is testingOpen Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUSWho this might be right forAtypical Hemolytic Uremic Syndrome Alexion Pharmaceuticals, Inc. 16
Large-scale testing (Phase 3)Study completedNCT03131219What this trial is testingStudy of Ravulizumab in Children and Adolescents With Atypical Hemolytic Uremic Syndrome (aHUS)Who this might be right forAtypical Hemolytic Uremic Syndrome (aHUS) Alexion Pharmaceuticals, Inc. 34
Not applicableStudy completedNCT00358306What this trial is testingThe Role of Endothelium Dysfunction in Progression of CKD (Chronic Kidney Disease) After AKI (Acute Kidney Injury)Who this might be right forAcute Renal FailureChronic Kidney FailureEndothelial Dysfunction+1 more University of Alabama at Birmingham 36
Not applicableLooking for participantsNCT06065852What this trial is testingNational Registry of Rare Kidney DiseasesWho this might be right forAdenine Phosphoribosyltransferase DeficiencyAH AmyloidosisAHL Amyloidosis+81 more UK Kidney Association 35,000
Not applicableActive Not RecruitingNCT05985122What this trial is testingNew Analytic Tools for aHUS and C3G DiagnosisWho this might be right forHemolytic-Uremic SyndromeMembranoproliferative GlomerulonephritisHealthy Mario Negri Institute for Pharmacological Research 180
Not applicableEnded earlyNCT04125290What this trial is testingUS Post-Marketing Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITI)Who this might be right forHairy Cell Leukemia AstraZeneca 2
Large-scale testing (Phase 3)Ended earlyNCT03205995What this trial is testingSafety and Efficacy Study of OMS721 in Patients With Atypical Hemolytic Uremic SyndromeWho this might be right forThrombotic MicroangiopathiesAtypical Hemolytic Uremic Syndrome Omeros Corporation 6