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Results for “Hematologic, Immune, or Bone Marrow Disorders”

520 trials

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Showing 20 of 520 results

Testing effectiveness (Phase 2)Study completedNCT00065260
What this trial is testing

Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic Anemia

Who this might be right for
Aplastic Anemia
National Heart, Lung, and Blood Institute (NHLBI) 54
Early research (Phase 1)Study completedNCT01300572
What this trial is testing

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Who this might be right for
Chronic Myelomonocytic LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Lymphoblastic Leukemia+3 more
Fred Hutchinson Cancer Center 16
Post-approval studies (Phase 4)Active Not RecruitingNCT02386800
What this trial is testing

CINC424A2X01B Rollover Protocol

Who this might be right for
Primary MyelofibrosisPolycythemia VeraGraft Versus Host Disease+2 more
Novartis Pharmaceuticals 279
Testing effectiveness (Phase 2)Active Not RecruitingNCT04233346
What this trial is testing

The Study for CML Who Failed Prior TKIs or With T315I Mutation or Ph+ ALL Who Failed Prior TKIs or With T315I Mutation

Who this might be right for
Chronic Myeloid LeukemiaAcute Lymphoblastic Leukemia
Otsuka Beijing Research Institute 93
Early research (Phase 1)Study completedNCT03263637
What this trial is testing

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Who this might be right for
Relapsed or Refractory Haematological Malignancies IncludingAcute Myeloid LeukemiaAcute Lymphocytic Leukemia+8 more
AstraZeneca 44
Testing effectiveness (Phase 2)Study completedNCT00171912
What this trial is testing

Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes

Who this might be right for
Hypereosinophilic SyndromeSystemic MastocytosisChronic Myelomonocytic Leukemia+1 more
Novartis Pharmaceuticals 38
Testing effectiveness (Phase 2)Study completedNCT01279473
What this trial is testing

Study to Evaluate Nilotinib in Adult Patients With Imatinib-resistant or Imatinib-intolerant Chronic Myelogenous Leukemia (CML), or Relapse/Refractory Ph+ Acute Lymphoblastic Leukemia (ALL) (Extension Study)

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia
Novartis Pharmaceuticals 42
Testing effectiveness (Phase 2)Study completedNCT03128359
What this trial is testing

High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant

Who this might be right for
Acute LeukemiaChronic Lymphocytic Leukemia/Small Lymphocytic LymphomaChronic Myelogenous Leukemia, BCR-ABL1 Positive+12 more
City of Hope Medical Center 38
Early research (Phase 1)Study completedNCT00077467
What this trial is testing

Bortezomib in Treating Young Patients With Refractory or Recurrent Leukemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaChildhood Acute Promyelocytic Leukemia (M3)Recurrent Childhood Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 36
Early research (Phase 1)Study completedNCT00004009
What this trial is testing

R115777 in Treating Patients With Refractory or Recurrent Acute Leukemia or Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
University of Maryland, Baltimore
Testing effectiveness (Phase 2)Study completedNCT00427765
What this trial is testing

Busulfan Plus Melphalan Conditioning Regimen for Lymphoid Malignancies or Multiple Myeloma

Who this might be right for
Multiple MyelomaLymphoma
M.D. Anderson Cancer Center 168
Early research (Phase 1)Looking for participantsNCT03595917
What this trial is testing

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaChronic Myeloid Leukemia (CML) in Lymphoid Blast CrisisPhiladelphia Chromosome Positive Acute Lymphoblastic Leukemia Ph+ ALL
Marlise Luskin, MD 40
Early research (Phase 1)Active Not RecruitingNCT04013685
What this trial is testing

Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoid LeukemiaMyelodysplastic Syndromes+3 more
Orca Biosystems, Inc. 155
Very early researchActive Not RecruitingNCT06765876
What this trial is testing

CART123 T Cells in Relapsed or Refractory CD123+ Hematologic Malignancies: A Dose Escalation Phase I Trial

Who this might be right for
Leukemia, Myeloid, Acute(AML)Precursor Cell Lymphoblastic Leukemia-LymphomaMyelodysplastic Syndromes (MDS)+1 more
Institute of Hematology and Blood Transfusion, Czech Republic 18
Early research (Phase 1)Ended earlyNCT03519984
What this trial is testing

EphB4-HSA Fusion Protein and Cytarabine /or Liposomal Vincristine in Patients With Recurrent or Refractory Acute Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlasts 5 Percent or More of Bone Marrow Nucleated CellsMyelodysplastic/Myeloproliferative Neoplasm+8 more
University of Southern California 3
Testing effectiveness (Phase 2)Ended earlyNCT00676806
What this trial is testing

A Phase II Study of Umbilical Cord Blood Transplantation

Who this might be right for
LeukemiaLymphomaMultiple Myeloma+1 more
Tufts Medical Center 7
Early research (Phase 1)Ended earlyNCT00672152
What this trial is testing

A Phase I Study of WT1 Peptides to Induce Anti-Leukemia Immune Responses Following Transplantation

Who this might be right for
Acute Myelogenous Leukemia (AML)Chronic Myelogenous Leukemia (CML)Acute Lymphoblastic Leukemia (ALL)+2 more
Michael Morse, MD 8
Large-scale testing (Phase 3)Active Not RecruitingNCT06475820
What this trial is testing

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaBiphenotypic Acute Leukemia+2 more
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 150
Early research (Phase 1)Study completedNCT00217646
What this trial is testing

Sorafenib in Treating Patients With Refractory or Relapsed Acute Leukemia, Myelodysplastic Syndromes, or Blastic Phase Chronic Myelogenous Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia+21 more
National Cancer Institute (NCI) 36
Early research (Phase 1)Study completedNCT02543879
What this trial is testing

Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Myelogenous LeukemiaMyelodysplastic Syndrome+1 more
Forma Therapeutics, Inc. 94
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