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Results for “Hemoglobin Mutations”

7 trials

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Showing 7 of 7 results

Large-scale testing (Phase 3)Ended earlyNCT05348915
What this trial is testing

Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseVaso-occlusive CrisisVaso-occlusive Pain Episode in Sickle Cell Disease
Pfizer 242
Testing effectiveness (Phase 2)Looking for participantsNCT05735717
What this trial is testing

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Who this might be right for
Hematologic MalignancyAcute LeukemiaRemission+19 more
Masonic Cancer Center, University of Minnesota 70
Large-scale testing (Phase 3)Active Not RecruitingNCT03814746
What this trial is testing

Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients

Who this might be right for
Sickle Cell Disease (SCD)
Novartis Pharmaceuticals 255
Large-scale testing (Phase 3)Ended earlyNCT04927247
What this trial is testing

A Single Dose of Inclacumab to Reduce Re-admission in Participants With Sickle Cell Disease and Recurrent Vaso-occlusive Crises

Who this might be right for
Sickle Cell DiseaseVaso-occlusive CrisisVaso-occlusive Pain Episode in Sickle Cell Disease
Pfizer 72
Not applicableStudy completedNCT00277849
What this trial is testing

Collection of Blood From Persons With Hemoglobin and Erythrocyte Polymorphisms for Laboratory Malaria Research

Who this might be right for
Hemoglobin MutationsErythrocyte Variants
National Institute of Allergy and Infectious Diseases (NIAID) 130
Large-scale testing (Phase 3)Study completedNCT04935879
What this trial is testing

Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises

Who this might be right for
Sickle Cell DiseaseVaso-occlusive Pain Episode in Sickle Cell DiseaseVaso-occlusive Crisis
Pfizer 241
Large-scale testing (Phase 3)Looking for participantsNCT06439082
What this trial is testing

Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Who this might be right for
Sickle Cell Disease
Novartis Pharmaceuticals 315