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Results for “Hemoglobinuria, Paroxysmal”

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Showing 20 of 0 results

Not applicableStudy completedNCT05842486
What this trial is testing

Hematological Response in Patients With Paroxysmal Nocturnal Hemoglobinuria Treated With Anti-C5 Antibody: an External Control Arm Study for Iptacopan Use in Anti-C5 naïve Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Assistance Publique - Hôpitaux de Paris 92
Large-scale testing (Phase 3)Looking for participantsNCT07154745
What this trial is testing

Evaluate How Pozelimab + Cemdisiran Combination Therapy Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Whose Current Treatment is Not Working Efficiently

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Regeneron Pharmaceuticals 35
Large-scale testing (Phase 3)Study completedNCT06715943
What this trial is testing

Efficacy and Safety of HRS-5965 in Patients With PNH Who Are Still Anemia After Anti-C5 Antibody Treatment

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Chengdu Suncadia Medicine Co., Ltd. 39
Testing effectiveness (Phase 2)Looking for participantsNCT07470762
What this trial is testing

Study of Safety and Efficacy of HS-10542 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Jiangsu Hansoh Pharmaceutical Co., Ltd. 50
Large-scale testing (Phase 3)Active Not RecruitingNCT05389449
What this trial is testing

A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 80
Large-scale testing (Phase 3)Study completedNCT04679103
What this trial is testing

A Safety and Immunogenicity Study in Long-term Treatment of Eculizumab (JSC "GENERIUM", Russian Federation)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
AO GENERIUM 50
Large-scale testing (Phase 3)Study completedNCT03588026
What this trial is testing

Treating Paroxysmal Nocturnal Haemoglobinuria Patients With rVA576

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
AKARI Therapeutics 9
Testing effectiveness (Phase 2)Study completedNCT03053102
What this trial is testing

Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Alexion Pharmaceuticals, Inc. 10
Testing effectiveness (Phase 2)Study completedNCT02352493
What this trial is testing

An Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Alnylam Pharmaceuticals 62
Early research (Phase 1)Study completedNCT07035665
What this trial is testing

A Clinical Study to Evaluate the Effect of Food on the Pharmacokinetic Profiles of HRS-5965 Capsules in Healthy Subjects

Who this might be right for
IgA NephropathyParoxysmal Nocturnal Hemoglobinuria
Chengdu Suncadia Medicine Co., Ltd. 16
Not applicableActive Not RecruitingNCT06633536
What this trial is testing

Real-life Treatment Outcomes of Ravulizumab in PNH

Who this might be right for
Paroxysmal Nocturnal Haemoglobinuria
AstraZeneca 64
Large-scale testing (Phase 3)Study completedNCT04469465
What this trial is testing

Danicopan as Add-on Therapy to a C5 Inhibitor in Paroxysmal Nocturnal Hemoglobinuria (PNH) Participants Who Have Clinically Evident Extravascular Hemolysis (EVH)(ALPHA)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 86
Testing effectiveness (Phase 2)Looking for participantsNCT06412497
What this trial is testing

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Who this might be right for
Severe Aplastic AnemiaAcquired Amegakaryocytic ThrombocytopeniaAcquired Pure Red Cell Aplasia+1 more
Masonic Cancer Center, University of Minnesota 60
Large-scale testing (Phase 3)Study completedNCT06799546
What this trial is testing

A Phase III Study to Evaluate the Efficacy and Safety of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Are Naive to Complement Inhibitor Therapy

Who this might be right for
PNH
Haisco Pharmaceutical Group Co., Ltd. 73
Testing effectiveness (Phase 2)Ended earlyNCT03333486
What this trial is testing

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Leukemia in RemissionAcute Lymphoblastic Leukemia+34 more
Roswell Park Cancer Institute 31
Large-scale testing (Phase 3)Study completedNCT03748823
What this trial is testing

Ravulizumab Subcutaneous (SC) Versus Ravulizumab Intravenous (IV) in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 139
Not applicableLooking for participantsNCT06931691
What this trial is testing

A Multi-center, Ambispective Cohort Study to Evaluate the Impact of Iptacopan for Adult Patients With PNH in China

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals 80
Testing effectiveness (Phase 2)UnknownNCT01642979
What this trial is testing

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaHemoglobinuriaHemoglobinuria, Paroxysmal+6 more
Institute of Hematology & Blood Diseases Hospital, China 120
Early research (Phase 1)Study completedNCT06852092
What this trial is testing

Study on Mass Balance of [14C]HSK39297 in Healthy Chinese Adult Male Subjects

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Haisco Pharmaceutical Group Co., Ltd. 7
Not applicableActive Not RecruitingNCT07413679
What this trial is testing

Long-term Safety of Danicopan: IPIG Registry-based Cohort Study

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaPNH
Alexion Pharmaceuticals, Inc. 50
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