Not applicableStudy completedNCT00721864What this trial is testingThe Molecular Biology of Paroxysmal Nocturnal Hemoglobinuria (PNH)Who this might be right forHemoglobinuria, Paroxysmal University of Utah 10
Early research (Phase 1)Study completedNCT05828472What this trial is testingMultiple Ascending Doses MY008211A in Healthy AdultsWho this might be right forParoxysmal Nocturnal Hemoglobinuria Wuhan Createrna Science and Technology Co., Ltd 40
Large-scale testing (Phase 3)Study completedNCT04469465What this trial is testingDanicopan as Add-on Therapy to a C5 Inhibitor in Paroxysmal Nocturnal Hemoglobinuria (PNH) Participants Who Have Clinically Evident Extravascular Hemolysis (EVH)(ALPHA)Who this might be right forParoxysmal Nocturnal Hemoglobinuria Alexion Pharmaceuticals, Inc. 86
Testing effectiveness (Phase 2)Study completedNCT02598583What this trial is testingDose-Escalation Study of ALXN1210 IV in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)Who this might be right forPNH Alexion Pharmaceuticals, Inc. 13
Testing effectiveness (Phase 2)Study completedNCT03053102What this trial is testingStudy of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)Who this might be right forParoxysmal Nocturnal Hemoglobinuria (PNH) Alexion Pharmaceuticals, Inc. 10
Testing effectiveness (Phase 2)Study completedNCT03157635What this trial is testingStudy to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal HemoglobinuriaWho this might be right forParoxysmal Hemoglobinuria, Nocturnal Hoffmann-La Roche 59
Testing effectiveness (Phase 2)UnknownNCT01642979What this trial is testingSafety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal HemoglobinuriaWho this might be right forParoxysmal Nocturnal HemoglobinuriaHemoglobinuriaHemoglobinuria, Paroxysmal+6 more Institute of Hematology & Blood Diseases Hospital, China 120
Early research (Phase 1)Looking for participantsNCT07760467What this trial is testingTo Evaluate Safety, Tolerability, PK/PD & Food Effect of Single/Multiple Oral TUL321 Capsules in Healthy Participants.Who this might be right forParoxysmal Nocturnal Hemoglobinuria, PNH Zhuhai United Laboratories Co., Ltd. 94
Testing effectiveness (Phase 2)Study completedNCT01192399What this trial is testingSafety and Efficacy Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria PatientsWho this might be right forParoxysmal Nocturnal Hemoglobinuria Alexion Pharmaceuticals, Inc. 29
Not applicableLooking for participantsNCT05755867What this trial is testingGlobal PNH Patient RegistryWho this might be right forParoxysmal Nocturnal Hemoglobinuria Aplastic Anemia and MDS International Foundation 500
Testing effectiveness (Phase 2)Study completedNCT03030183What this trial is testingPhase 2 Safety and Efficacy Study of Zilucoplan (RA101495) to Treat PNH Patients Who Have an Inadequate Response to EculizumabWho this might be right forParoxysmal Nocturnal Hemoglobinuria (PNH) Ra Pharmaceuticals 3
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07796256What this trial is testingStudy of SGB-9768 in Patients With Paroxysmal Nocturnal HemoglobinuriaWho this might be right forPNH - Paroxysmal Nocturnal Hemoglobinuria Suzhou Sanegene Bio Inc. 24
Not applicableNot Yet RecruitingNCT07788105What this trial is testingEfficacy and Safety of Lanoracopan in the Treatment of PNHWho this might be right forParoxysmal Nocturnal Hemoglobinuria, PNH Peking Union Medical College Hospital 90
Not applicableActive Not RecruitingNCT07413679What this trial is testingLong-term Safety of Danicopan: IPIG Registry-based Cohort StudyWho this might be right forParoxysmal Nocturnal HemoglobinuriaPNH Alexion Pharmaceuticals, Inc. 50
Testing effectiveness (Phase 2)Study completedNCT01529827What this trial is testingFludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic MalignanciesWho this might be right forAccelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+75 more Roswell Park Cancer Institute 94
Not applicableUnknownNCT01224483What this trial is testingMulticenter Retrospective Analysis About the Clinical Characteristics of Korean Paroxysmal Nocturnal Hemoglobinuria (PNH) PatientsWho this might be right forHemoglobinuria, Paroxysmal Samsung Medical Center 350
Large-scale testing (Phase 3)Active Not RecruitingNCT05133531What this trial is testingEvaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor TreatmentWho this might be right forParoxysmal Nocturnal Hemoglobinuria Regeneron Pharmaceuticals 202
Testing effectiveness (Phase 2)Study completedNCT03439839What this trial is testingStudy of Safety, Efficacy, Tolerability, Pharmacokinetics and Pharmacodynamics of LNP023 in in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)Who this might be right forParoxysmal Nocturnal Hemoglobinuria (PNH) With Signs of Active Hemolysis Novartis Pharmaceuticals 16
Testing effectiveness (Phase 2)Study completedNCT06050226What this trial is testingMY008211A in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)Who this might be right forParoxysmal Nocturnal Hemoglobinuria Wuhan Createrna Science and Technology Co., Ltd 34
Early research (Phase 1)Study completedNCT05490017What this trial is testingTo Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Single and Multiple Doses of KP104Who this might be right forParoxysmal Nocturnal Hemoglobinuria Kira Pharmacenticals (US), LLC. 80