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Results for “Hemoglobinuria, Paroxysmal Nocturnal (PNH)”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Looking for participantsNCT06933914
What this trial is testing

Long-term Safety and Tolerability of MY008211A Tablets in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Wuhan Createrna Science and Technology Co., Ltd 120
Early research (Phase 1)Looking for participantsNCT07152288
What this trial is testing

Investigation of Pharmacokinetics,Safety,and Pharmacodynamics of HSK39297 in Subjects With Hepatic Impairment

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Haisco Pharmaceutical Group Co., Ltd. 24
Large-scale testing (Phase 3)Looking for participantsNCT06449001
What this trial is testing

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaPNHExtravascular Hemolysis
Alexion Pharmaceuticals, Inc. 6
Early research (Phase 1)Study completedNCT03316521
What this trial is testing

First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers

Who this might be right for
Complement Mediated Diseases
Amyndas Pharmaceuticals S.A. 50
Large-scale testing (Phase 3)Study completedNCT06593938
What this trial is testing

Evaluate the Efficacy and Safety of Oral HRS-5965 in Adult Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Who Are Naive to Complement Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Chengdu Suncadia Medicine Co., Ltd. 76
Testing effectiveness (Phase 2)Ended earlyNCT03225287
What this trial is testing

Extension Study of RA101495 for Patients With PNH Who Have Completed a Zilucoplan (RA101495) Clinical Study

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Ra Pharmaceuticals, Inc. 19
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05646563
What this trial is testing

Study of NM8074 in Adult PNH Patients With Inadequate Response to Soliris

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
NovelMed Therapeutics 12
Large-scale testing (Phase 3)Study completedNCT06715943
What this trial is testing

Efficacy and Safety of HRS-5965 in Patients With PNH Who Are Still Anemia After Anti-C5 Antibody Treatment

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Chengdu Suncadia Medicine Co., Ltd. 39
Early research (Phase 1)Study completedNCT02588833
What this trial is testing

Pilot Study to Assess Safety, Preliminary Efficacy and Pharmacokinetics of S.C. Pegcetacoplan (APL-2) in PNH Subjects.

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Apellis Pharmaceuticals, Inc. 23
Testing effectiveness (Phase 2)Ended earlyNCT04702568
What this trial is testing

A Long-Term Safety Study of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaPNH
BioCryst Pharmaceuticals 19
Large-scale testing (Phase 3)Study completedNCT04820530
What this trial is testing

Study of Efficacy and Safety of Twice Daily Oral Iptacopan (LNP023) in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Novartis Pharmaceuticals 40
Large-scale testing (Phase 3)Looking for participantsNCT07154745
What this trial is testing

Evaluate How Pozelimab + Cemdisiran Combination Therapy Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Whose Current Treatment is Not Working Efficiently

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Regeneron Pharmaceuticals 35
Large-scale testing (Phase 3)Study completedNCT00122330
What this trial is testing

Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Who this might be right for
Hemoglobinuria, Paroxysmal
Alexion Pharmaceuticals, Inc. 75
Not applicableLooking for participantsNCT06411626
What this trial is testing

Home Reported Outcomes in PNH

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals 128
Testing effectiveness (Phase 2)Looking for participantsNCT06978699
What this trial is testing

A Phase II Study Evaluating the Efficacy and Safety of XH-S003 Capsules in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
PNH - Paroxysmal Nocturnal Hemoglobinuria
S-INFINITY Pharmaceuticals Co., Ltd 24
Early research (Phase 1)Looking for participantsNCT07462780
What this trial is testing

A Phase I Clinical Trial to Evaluate CMS-D017 Following Single and Multiple Doses in Healthy Participants

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria, PNHComplement-mediated Kidney Disease
Shenzhen Kangzhe Biotechnology Co., Ltd. 88
Testing effectiveness (Phase 2)Active Not RecruitingNCT06298955
What this trial is testing

Long-Term Safety, Tolerability and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Omeros Corporation 25
Not applicableLooking for participantsNCT07229235
What this trial is testing

REAL-CARE: Real-world Effectiveness of Iptacopan in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Novartis Pharmaceuticals 50
Not applicableLooking for participantsNCT04645199
What this trial is testing

National Longitudinal Cohort of Hematological Diseases

Who this might be right for
Multiple MyelomaAcute Myeloid LeukemiaHemophilia+14 more
Institute of Hematology & Blood Diseases Hospital, China 2,300
Early research (Phase 1)Study completedNCT05889299
What this trial is testing

Study of the Safety and Efficacy of OMS906 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Omeros Corporation 15
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