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Results for “Hemoglobinuria, Paroxysmal Nocturnal (PNH)”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT00122304
What this trial is testing

Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab

Who this might be right for
Hemoglobinuria, Paroxysmal
Alexion Pharmaceuticals, Inc. 85
Testing effectiveness (Phase 2)Study completedNCT00004464
What this trial is testing

Study of High Dose Cyclophosphamide in Patients With Severe Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Aplastic AnemiaParoxysmal Hemoglobinuria, Nocturnal
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 69
Testing effectiveness (Phase 2)Study completedNCT03593200
What this trial is testing

A Phase IIa Study to Assess the Safety, Efficacy, and Pharmacokinetics of Subcutaneously Administered Pegcetacoplan (APL-2) in Subjects With PNH

Who this might be right for
PNH
Apellis Pharmaceuticals, Inc. 4
Not applicableActive Not RecruitingNCT03329365
What this trial is testing

Paroxysmal Nocturnal Hemoglobinuria in ESUS & ETUS

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaEmbolic Stroke of Undetermined SourceTransient Ischemic Attack+1 more
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 200
Not applicableStudy completedNCT01412047
What this trial is testing

Paroxysmal Nocturnal Hemoglobinuria Human Anti-Human Antibodies Study

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaPNH
Alexion Pharmaceuticals, Inc. 75
Testing effectiveness (Phase 2)Study completedNCT03946748
What this trial is testing

Study to Evaluate the Efficacy and Safety of REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Regeneron Pharmaceuticals 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT06238544
What this trial is testing

Long-term Safety and Tolerability of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Chengdu Suncadia Medicine Co., Ltd. 132
Testing effectiveness (Phase 2)Study completedNCT04888507
What this trial is testing

Pozelimab and Cemdisiran Combination Therapy in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Who Switch From Eculizumab Therapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Regeneron Pharmaceuticals 6
Testing effectiveness (Phase 2)Ended earlyNCT03333486
What this trial is testing

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Leukemia in RemissionAcute Lymphoblastic Leukemia+34 more
Roswell Park Cancer Institute 31
Not applicableActive Not RecruitingNCT06633536
What this trial is testing

Real-life Treatment Outcomes of Ravulizumab in PNH

Who this might be right for
Paroxysmal Nocturnal Haemoglobinuria
AstraZeneca 64
Not applicableLooking for participantsNCT07416162
What this trial is testing

Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 Glomerulopathy

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaC3 Glomerulopathy
Novartis Pharmaceuticals 21
Testing effectiveness (Phase 2)Ended earlyNCT05741346
What this trial is testing

Long-term Safety of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
BioCryst Pharmaceuticals 28
Large-scale testing (Phase 3)Study completedNCT04058158
What this trial is testing

Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Samsung Bioepis Co., Ltd. 50
Testing effectiveness (Phase 2)Study completedNCT02352493
What this trial is testing

An Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Alnylam Pharmaceuticals 62
Large-scale testing (Phase 3)Study completedNCT03531255
What this trial is testing

Pegcetacoplan Long Term Safety and Efficacy Extension Study

Who this might be right for
PNH
Apellis Pharmaceuticals, Inc. 137
Not applicableStudy completedNCT01374360
What this trial is testing

Paroxysmal Nocturnal Hemoglobinuria (PNH) Registry

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 6,061
Early research (Phase 1)UnknownNCT06543459
What this trial is testing

To Evaluate the Effect of Single Oral Dose of MY008211A Tablets on QTc Interval in Healthy Subjects

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Wuhan Createrna Science and Technology Co., Ltd 16
Not applicableNo Longer AvailableNCT06028594
What this trial is testing

Compassionate Use of Pozelimab and Cemdisiran Combination Therapy in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Regeneron Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT02591862
What this trial is testing

Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Haemoglobinuria (PNH)
AKARI Therapeutics 1
Testing effectiveness (Phase 2)UnknownNCT01760096
What this trial is testing

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013)

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaHemoglobinuriaHemoglobinuria, Paroxysmal+6 more
Institute of Hematology & Blood Diseases Hospital, China 50
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