Large-scale testing (Phase 3)Ended earlyNCT04218084What this trial is testingStudy to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Pfizer 236
Not applicableNot Yet RecruitingNCT06769139What this trial is testingEvaluation of the Impact of Red Blood Cell Exchange on Thrombo-inflammation in Sickle Cell DiseaseWho this might be right forSickle Cell Disease University Hospital, Toulouse 20
Post-approval studies (Phase 4)UnknownNCT03392298What this trial is testingStudy on the Mechanism of Colla Corri Asini in the Treatment of Thalassemia Patients With Pregnancy AnemiaWho this might be right forThalassemiaPregnancy The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine 70
Not applicableEnrolling By InvitationNCT06300723What this trial is testingClinical Study of BRL-101 in Severe SCDWho this might be right forSickle Cell Disease Bioray Laboratories 3
Not applicableStudy completedNCT00736060What this trial is testingClinical and Laboratory Characteristics of Sickle Cell Anemia Patients Admitted With FeverWho this might be right forSickle Cell AnemiaSickle Cell Thalassemia HaEmek Medical Center, Israel 60
Early research (Phase 1)Study completedNCT06581627What this trial is testingA Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese ParticipantsWho this might be right forHealthy VolunteersSickle Cell DiseaseThalassemia Novo Nordisk A/S 24
Post-approval studies (Phase 4)Ended earlyNCT00880373What this trial is testingIbuprofen and Opioid (Morphine or Diamorphine) for Acute Pain in Sickle Cell Disease - Sickle With Ibuprofen & MorphineWho this might be right forSickle Cell Disease London North West Healthcare NHS Trust 320
Not applicableLooking for participantsNCT06074198What this trial is testingSickle Cell Children's Exercise Study (SuCCESs)Who this might be right forSickle Cell Disease University of Maryland, Baltimore 20
Not applicableStudy completedNCT00789516What this trial is testingThe Change of Coagulation Markers in Children With β-thalassemia Disease After Stem Cell TransplantationWho this might be right forThalassemia Mahidol University 60
Not applicableStudy completedNCT03488264What this trial is testingStigma, Self-management, & Quality of Life in SCDWho this might be right forSickle Cell DiseaseQuality of LifeStigma, Social+1 more Duke University 102
Not applicableLooking for participantsNCT06941389What this trial is testingComparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease (SCD) University of Rochester 480
Not applicableUnknownNCT04264871What this trial is testingIs the Preoperative Preparation of Sickle Cell Patients Optimal: Assessment of Practices and Post-operative ComplicationsWho this might be right forSickle Cell Disease Queen Fabiola Children's University Hospital 250
Testing effectiveness (Phase 2)Study completedNCT02140554What this trial is testingA Study Evaluating the Safety and Efficacy of Lovo-cel in Severe Sickle Cell DiseaseWho this might be right forSickle Cell Disease Genetix Biotherapeutics Inc. 54
Not applicableStudy completedNCT04505969What this trial is testingA Study Aimed to Assess the Needs of Subjects With Sickle Cell Disease and Healthcare Professionals Managing Sickle Cell Disease Patients in Selected Nigerian CentresWho this might be right forSickle Cell Disease Fondazione per la Ricerca Farmacologica Gianni Benzi Onlus 192
Early research (Phase 1)Active Not RecruitingNCT03249831What this trial is testingA Blood Stem Cell Transplant for Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseSickle Cell DisorderHemoglobinopathies+2 more City of Hope Medical Center 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT04610866What this trial is testingSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of MitapivatWho this might be right forSickle Cell DiseaseHemolytic Anemia National Heart, Lung, and Blood Institute (NHLBI) 15
Testing effectiveness (Phase 2)Study completedNCT00349453What this trial is testingStudy Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-dependent PatientsWho this might be right forHemochromatosis Lipomed 24
Post-approval studies (Phase 4)Study completedNCT04581356What this trial is testingVoxelotor Sickle Cell Exercise StudyWho this might be right forSickle Cell Anemia Elizabeth Yang, MD, PhD 14
Large-scale testing (Phase 3)Study completedNCT03704922What this trial is testingAge of Blood in Sickle Cell TransfusionWho this might be right forSickle Cell Disease University of North Carolina, Chapel Hill 26
Post-approval studies (Phase 4)Study completedNCT02342145What this trial is testingEfficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia MajorWho this might be right forBeta-Thalassemia MajorGraft-versus-host Disease (GVHD) Zhongming Zhang 205