Large-scale testing (Phase 3)Ended earlyNCT05561140What this trial is testingResolution of Sickle Cell Leg Ulcers With VoxelotorWho this might be right forSickle Cell DiseaseLeg Ulcers Pfizer 88
Testing effectiveness (Phase 2)Study completedNCT03806452What this trial is testingSIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial)Who this might be right forSickle Cell Disease Theravia 86
Testing effectiveness (Phase 2)Looking for participantsNCT06198712What this trial is testingEvaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Forma Therapeutics, Inc. 95
Testing effectiveness (Phase 2)Active Not RecruitingNCT05664737What this trial is testingDetermine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-ThalassemiaWho this might be right forAnemia Bristol-Myers Squibb 189
Large-scale testing (Phase 3)Study completedNCT07782931What this trial is testingEvaluate the Efficacy and Safety of Irochel for the Management of Iron Overload in Thalassemia Patients in Comparison With DeferoxamineWho this might be right forIron Overload Due to Repeated Red Blood Cell TransfusionsThalassemia Majors (Beta-Thalassemia Major) Hamdard University 132
Post-approval studies (Phase 4)UnknownNCT03392298What this trial is testingStudy on the Mechanism of Colla Corri Asini in the Treatment of Thalassemia Patients With Pregnancy AnemiaWho this might be right forThalassemiaPregnancy The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine 70
Not applicableLooking for participantsNCT06147414What this trial is testingDevelopment of Non-Invasive Prenatal Diagnosis for Single Gene DisordersWho this might be right forInvasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, IncludingSickle Cell DiseaseCystic Fibrosis+12 more Assistance Publique - Hôpitaux de Paris 550
Testing effectiveness (Phase 2)Looking for participantsNCT05953584What this trial is testingOpen-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary StrokeWho this might be right forSickle Cell Disease Forma Therapeutics, Inc. 27
Testing effectiveness (Phase 2)Ended earlyNCT01987908What this trial is testingEvaluation of Different Dose Regimens of Aes-103 Given for 28 Days to Subjects With Stable Sickle Cell DiseaseWho this might be right forSickle Cell Disease Baxalta now part of Shire 35
Not applicableStudy completedNCT04756375What this trial is testingEvaluation of Virtual Reality to Save Morphinic in the Treatment of Vaso-occlusive Seizures of Sickle Cell Patients Consulting in the Emergency RoomWho this might be right forVaso-occlusive CrisisSickle Cell Disease Assistance Publique - Hôpitaux de Paris 97
Not applicableStudy completedNCT06144801What this trial is testingThe Effect of Coolsense Method on Pain and Comfort in Hemodialysis PatientsWho this might be right forHemolysisComplementary TherapyPain+1 more Karadeniz Technical University 50
Not applicableStudy completedNCT02386657What this trial is testingSingle-center Prospective Evaluation of Sickle Cell Patient Care in the CHU Brugmann Emergency DepartmentWho this might be right forSickle Cell Disease Brugmann University Hospital 104
Early research (Phase 1)Study completedNCT03126695What this trial is testingCompare if the Uptake of Ticagrelor in the Body Differs When Different Tablets Are AdministeredWho this might be right forSickle Cell Disease AstraZeneca 44
Large-scale testing (Phase 3)Active Not RecruitingNCT04293185What this trial is testingA Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell DiseaseWho this might be right forSickle Cell Disease Genetix Biotherapeutics Inc. 35
Large-scale testing (Phase 3)Ended earlyNCT04076748What this trial is testingEvaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults.Who this might be right forSickle Cell Crisis University Hospital, Bordeaux 115
Testing effectiveness (Phase 2)Ended earlyNCT01522196What this trial is testingVarespladib Infusion in Subjects With Sickle Cell Disease.Who this might be right forSickle Cell DiseaseVaso-occlusive Crisis Anthera Pharmaceuticals 2
Post-approval studies (Phase 4)Study completedNCT01610297What this trial is testingPost Hematopoietic Stem Cell TransplantationWho this might be right forIron Overload After Hematopoietic Stem Cell Transplantation (HSCT) in Patients With Beta-thalassemia Major Novartis Pharmaceuticals 27
Early research (Phase 1)Study completedNCT06581627What this trial is testingA Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese ParticipantsWho this might be right forHealthy VolunteersSickle Cell DiseaseThalassemia Novo Nordisk A/S 24
Large-scale testing (Phase 3)Study completedNCT01863173What this trial is testingEffect of Metoprolol on Thalassemia CardiomyopathyWho this might be right forB Thalassemia Shiraz University of Medical Sciences 45
Not applicableStudy completedNCT01715480What this trial is testingEffect of Broccoli Sprouts Homogenate on SS RBCWho this might be right forSickle Red Blood CellFetal HemoglobinOxidative Stress Duke University 21