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Results for “Hemolytic Uremic Syndrome, Atypical”

48 trials

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Showing 20 of 48 results

Not applicableUnknownNCT03605511
What this trial is testing

TTP and aHUS in Complicated Pregnancies

Who this might be right for
Thrombotic Thrombocytopenic PurpuraAtypical Hemolytic Uremic SyndromePre-Eclampsia+5 more
University College, London 150
Large-scale testing (Phase 3)Active Not RecruitingNCT04889430
What this trial is testing

Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 34
Large-scale testing (Phase 3)Looking for participantsNCT05795140
What this trial is testing

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 125
Post-approval studies (Phase 4)Looking for participantsNCT07308574
What this trial is testing

Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS

Who this might be right for
aHUSAtypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 20
Large-scale testing (Phase 3)Looking for participantsNCT05726916
What this trial is testing

Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome

Who this might be right for
Hypertensive Emergency-associated Hemolytic Uremic Syndrome
Assistance Publique - Hôpitaux de Paris 66
Not applicableStudy completedNCT05405777
What this trial is testing

A Retrospective Study to Evaluate the Clinical Outcome According to Treatment in aHUS Patients in South Korea

Who this might be right for
aHUS
Handok Inc. 97
Large-scale testing (Phase 3)Looking for participantsNCT05935215
What this trial is testing

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 50
Not applicableLooking for participantsNCT06312644
What this trial is testing

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Who this might be right for
Ultomiris-exposed Pregnant/ PostpartumPregnancyParoxysmal Nocturnal Hemoglobinuria (PNH)+3 more
Alexion Pharmaceuticals, Inc. 75
Early research (Phase 1)Study completedNCT06004947
What this trial is testing

A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications

Who this might be right for
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Amgen 32
Testing effectiveness (Phase 2)Study completedNCT01757431
What this trial is testing

The Safety and Efficacy of Eculizumab in Japanese Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome (aHUS)
Alexion Pharmaceuticals, Inc. 2
Testing effectiveness (Phase 2)Study completedNCT01193348
What this trial is testing

An Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic Syndrome

Who this might be right for
Atypical Hemolytic-Uremic Syndrome
Alexion Pharmaceuticals, Inc. 22
Not applicableLooking for participantsNCT05805202
What this trial is testing

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 112
Large-scale testing (Phase 3)Active Not RecruitingNCT04958265
What this trial is testing

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Hoffmann-La Roche 41
Large-scale testing (Phase 3)Study completedNCT04859608
What this trial is testing

Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU)

Who this might be right for
Hemolytic-Uremic Syndrome, Atypical
University Hospital, Tours 40
Testing effectiveness (Phase 2)Ended earlyNCT02464891
What this trial is testing

Complement Inhibition in aHUS Dialysis Patients

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 6
Testing effectiveness (Phase 2)WithdrawnNCT03303313
What this trial is testing

An Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alnylam Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT03131219
What this trial is testing

Study of Ravulizumab in Children and Adolescents With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome (aHUS)
Alexion Pharmaceuticals, Inc. 34
Not applicableWithdrawnNCT02626663
What this trial is testing

The Role of Microparticles as a Biomarker

Who this might be right for
Atypical Hemolytic Uremic SyndromeThrombotic Thrombocytopenic PurpuraMicroparticles+1 more
University of Rochester
Not applicableLooking for participantsNCT04745195
What this trial is testing

Complement Prospective Evaluation of Thrombotic Microangiopathy on Endothelium

Who this might be right for
Thrombotic MicroangiopathiesHemolytic Uremic Syndrome, AtypicalHemolytic-Uremic Syndrome
Maastricht University Medical Center 42
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05684159
What this trial is testing

Study of NM8074 in Patients With aHUS With Evidence of Ongoing Thrombotic Microangiopathy

Who this might be right for
aHUS - Atypical Hemolytic Uremic Syndrome
NovelMed Therapeutics 12
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