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Results for “Hemolytic-Uremic Syndrome”

77 trials

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Showing 20 of 77 results

Large-scale testing (Phase 3)Ended earlyNCT00004465
What this trial is testing

Phase III Randomized Study of SYNSORB Pk in Children With E. Coli-Associated Hemolytic Uremic Syndrome

Who this might be right for
Hemolytic Uremic Syndrome
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 145
Not applicableUnknownNCT03605511
What this trial is testing

TTP and aHUS in Complicated Pregnancies

Who this might be right for
Thrombotic Thrombocytopenic PurpuraAtypical Hemolytic Uremic SyndromePre-Eclampsia+5 more
University College, London 150
Large-scale testing (Phase 3)Active Not RecruitingNCT04889430
What this trial is testing

Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 34
Not applicableStudy completedNCT02134171
What this trial is testing

Early Predictive Factors of Cardiac and Cerebral Involvement in TMA

Who this might be right for
Thrombotic MicroangiopathiesThrombotic Thrombocytopenic Purpura
Assistance Publique - Hôpitaux de Paris 119
Large-scale testing (Phase 3)Study completedNCT02205541
What this trial is testing

Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHU

Who this might be right for
Hemolytic Uremic Syndrome of Childhood
University Hospital, Toulouse 100
Large-scale testing (Phase 3)Looking for participantsNCT05795140
What this trial is testing

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 125
Post-approval studies (Phase 4)Looking for participantsNCT07308574
What this trial is testing

Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS

Who this might be right for
aHUSAtypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 20
Not applicableActive Not RecruitingNCT05985122
What this trial is testing

New Analytic Tools for aHUS and C3G Diagnosis

Who this might be right for
Hemolytic-Uremic SyndromeMembranoproliferative GlomerulonephritisHealthy
Mario Negri Institute for Pharmacological Research 180
Not applicableStudy completedNCT01561248
What this trial is testing

Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic Colitis

Who this might be right for
Hemolytic Uremic SyndromeHemorrhagic ColitisIntestinal Infectious Disease+1 more
Universitätsklinikum Hamburg-Eppendorf 33
Large-scale testing (Phase 3)Looking for participantsNCT05726916
What this trial is testing

Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome

Who this might be right for
Hypertensive Emergency-associated Hemolytic Uremic Syndrome
Assistance Publique - Hôpitaux de Paris 66
Not applicableStudy completedNCT05405777
What this trial is testing

A Retrospective Study to Evaluate the Clinical Outcome According to Treatment in aHUS Patients in South Korea

Who this might be right for
aHUS
Handok Inc. 97
Large-scale testing (Phase 3)Looking for participantsNCT05935215
What this trial is testing

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 50
Not applicableLooking for participantsNCT06312644
What this trial is testing

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Who this might be right for
Ultomiris-exposed Pregnant/ PostpartumPregnancyParoxysmal Nocturnal Hemoglobinuria (PNH)+3 more
Alexion Pharmaceuticals, Inc. 75
Not applicableStudy completedNCT02904863
What this trial is testing

Study of 'Vascular Competence' Profile and Endothelial Activation in the Hemolytic Uremic Syndrome in Children and Adults

Who this might be right for
Hemolytic Uremic Syndrome
Assistance Publique Hopitaux De Marseille 19
Early research (Phase 1)Study completedNCT06004947
What this trial is testing

A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications

Who this might be right for
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Amgen 32
Testing effectiveness (Phase 2)Study completedNCT01757431
What this trial is testing

The Safety and Efficacy of Eculizumab in Japanese Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome (aHUS)
Alexion Pharmaceuticals, Inc. 2
Not applicableStudy completedNCT01666548
What this trial is testing

Haemolytic Uraemic Syndrome in Childhood: Clinical, Cognitive and Psychological Aspects

Who this might be right for
Hemolytic-Uremic SyndromeChildrenParents+1 more
University Children's Hospital, Zurich 89
Testing effectiveness (Phase 2)Study completedNCT01193348
What this trial is testing

An Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic Syndrome

Who this might be right for
Atypical Hemolytic-Uremic Syndrome
Alexion Pharmaceuticals, Inc. 22
Not applicableLooking for participantsNCT05805202
What this trial is testing

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 112
Large-scale testing (Phase 3)Active Not RecruitingNCT04958265
What this trial is testing

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Hoffmann-La Roche 41
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