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Results for “Hemophilia B, Severe”

79 trials

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Showing 20 of 79 results

Early research (Phase 1)Ended earlyNCT01620801
What this trial is testing

Hemophilia B Gene Therapy With AAV8 Vector

Who this might be right for
Hemophilia B
Spark Therapeutics, Inc. 4
Large-scale testing (Phase 3)Study completedNCT03938792
What this trial is testing

Study of the Efficacy and Safety PF-06741086 in Adult and Teenage Participants With Severe Hemophilia A or Moderately Severe to Severe Hemophilia B

Who this might be right for
Hemophilia AHemophilia B
Pfizer 189
Not applicableStudy completedNCT00195221
What this trial is testing

Study to Describe the Allergic Reactions to Factor IX in Patients With Hemophilia B

Who this might be right for
Hemophilia BAllergic Reactions
Wyeth is now a wholly owned subsidiary of Pfizer 166
Not applicableStudy completedNCT05617209
What this trial is testing

In Vitro Correction of Thrombin Generation by Concizumab (Anti-TFPI) for Severe Hemophilia Patients

Who this might be right for
Hemophilia
Centre Hospitalier Universitaire de Saint Etienne 20
Not applicableStudy completedNCT00936312
What this trial is testing

Females With Severe or Moderate Hemophilia A or B: an International Multi-center Study

Who this might be right for
Hemophilia AHemophilia B
Weill Medical College of Cornell University 200
Large-scale testing (Phase 3)Study completedNCT02250560
What this trial is testing

Investigate the Safety and Efficacy of Replenine®-VF in Haemophilia B Patients Undergoing Major Surgery.

Who this might be right for
Haemophilia B
Bio Products Laboratory
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableWithdrawnNCT04541875
What this trial is testing

Medication Adherence and Non-adherence in Adults With Rare Disease

Who this might be right for
Cystic FibrosisHemophilia AHemophilia B+3 more
Xperiome
Large-scale testing (Phase 3)Study completedNCT01286779
What this trial is testing

BAX 326 (rFIX) Continuation Study

Who this might be right for
Hemophilia B
Baxalta now part of Shire 117
Large-scale testing (Phase 3)Study completedNCT01425723
What this trial is testing

Long-Term Safety and Efficacy of rFIXFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia B

Who this might be right for
Severe Hemophilia B
Bioverativ Therapeutics Inc. 120
Testing effectiveness (Phase 2)Looking for participantsNCT06379789
What this trial is testing

Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B

Who this might be right for
Hemophilia B
Regeneron Pharmaceuticals 130
Not applicableStudy completedNCT04590950
What this trial is testing

Dosage and PD Study of Eftrenonacog-alfa

Who this might be right for
Severe Haemophilia B
Assistance Publique - Hôpitaux de Paris 15
Not applicableStudy completedNCT02971969
What this trial is testing

Long-Term Safety, Tolerability, and Efficacy of DTX101 (AAVrh10FIX) in Adults With Moderate/Severe to Severe Hemophilia B

Who this might be right for
Hemophilia B
Ultragenyx Pharmaceutical Inc 6
Testing effectiveness (Phase 2)Study completedNCT03370172
What this trial is testing

BAX 888 in Male Adults With Severe Hemophilia A

Who this might be right for
Hemophilia A
Baxalta now part of Shire 4
Post-approval studies (Phase 4)UnknownNCT04534751
What this trial is testing

Factor In the Initial Resuscitation of Severe Trauma 2 Patients

Who this might be right for
Traumatic HemorrhageCoagulopathyMassive Hemorrhage
University Health Network, Toronto 350
Post-approval studies (Phase 4)Study completedNCT00638001
What this trial is testing

Impact of Conservative Treatment by Custom-made Orthoses in Patients With Haemophilic Ankle Arthropathy

Who this might be right for
Haemophilia AHaemophilia B
Cliniques universitaires Saint-Luc- Université Catholique de Louvain 70
Large-scale testing (Phase 3)Study completedNCT00093210
What this trial is testing

Study Evaluating of Recombinant Human Factor IX (BeneFIX) and a New Formulation of BeneFIX (rFIX-R) in Moderate to Severe Hemophilia B

Who this might be right for
Hemophilia B
Wyeth is now a wholly owned subsidiary of Pfizer
Testing effectiveness (Phase 2)Study completedNCT01361126
What this trial is testing

A Safety and Efficacy Study of a Recombinant Factor IX in Patients With Severe Hemophilia B

Who this might be right for
Hemophilia B
CSL Behring 17
Post-approval studies (Phase 4)Study completedNCT00092976
What this trial is testing

Study Evaluating ReFacto® in Hemophilia A Undergoing Major Surgery

Who this might be right for
Hemophilia A
Wyeth is now a wholly owned subsidiary of Pfizer 15
Large-scale testing (Phase 3)Study completedNCT03587116
What this trial is testing

Evaluate Prospective Efficacy and Safety Data of Current FIX Prophylaxis Replacement Therapy in Adult Hemophilia B Subjects (FIX:C≤2%) or Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Subjects (FVIII:C≤1%)

Who this might be right for
Hemophilia BHemophilia A
Pfizer 212
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