Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Hepatocellular Carcinoma, Unresectable, Advanced”

242 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 242 results

Testing effectiveness (Phase 2)Looking for participantsNCT07227012
What this trial is testing

Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

Who this might be right for
Carcinoma, HepatocellularHepatocellular CancerHepatocellular Carcinoma+4 more
Pfizer 138
Testing effectiveness (Phase 2)Study completedNCT05517239
What this trial is testing

Gemcitabine With Oxaliplatin (GEMOX) in Patients With Advanced Hepatocellular Carcinoma After Failure of Sorafenib Treatment

Who this might be right for
Hepatocellular Carcinoma, Unresectable, Advanced
Yonsei University 32
Testing effectiveness (Phase 2)Study completedNCT00003557
What this trial is testing

Dolastatin 10 in Treating Patients With Metastatic Or Recurrent Liver, Bile Duct, or Gallbladder Cancer

Who this might be right for
Extrahepatic Bile Duct CancerGallbladder CancerLiver Cancer
University of Chicago 16
Testing effectiveness (Phase 2)Study completedNCT00107536
What this trial is testing

Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer

Who this might be right for
Adult Primary Hepatocellular CarcinomaAdvanced Adult Primary Liver CancerLocalized Unresectable Adult Primary Liver Cancer+5 more
National Cancer Institute (NCI) 26
Large-scale testing (Phase 3)Looking for participantsNCT05985798
What this trial is testing

Sintilimab+Bevacizumab+TACE vs. Lenvatinib+TACE for Advanced HCC

Who this might be right for
Hepatocellular Carcinoma Non-resectable
Second Affiliated Hospital of Guangzhou Medical University 258
Testing effectiveness (Phase 2)Study completedNCT00003907
What this trial is testing

Chemoembolization in Treating Patients With Primary Liver Cancer or Metastases to the Liver

Who this might be right for
Liver CancerMetastatic Cancer
Eastern Cooperative Oncology Group 50
Large-scale testing (Phase 3)Active Not RecruitingNCT03298451
What this trial is testing

Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
AstraZeneca 1,324
Testing effectiveness (Phase 2)WithdrawnNCT03563170
What this trial is testing

QUILT-3.072: NANT Hepatocellular Carcinoma (HCC) Vaccine

Who this might be right for
Hepatocellular Carcinoma Non-resectableHepatocellular Carcinoma Recurrent
ImmunityBio, Inc.
Early research (Phase 1)Study completedNCT02578602
What this trial is testing

MRI With Gadoxetate Disodium in Measuring Tumors in Patients With Liver Cancer

Who this might be right for
Adult Hepatocellular CarcinomaAdvanced Adult Hepatocellular CarcinomaBCLC Stage 0 Adult Hepatocellular Carcinoma+6 more
University of Southern California 26
Early research (Phase 1)Study completedNCT02572687
What this trial is testing

Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaNon-Small Cell Lung Cancer+1 more
Eli Lilly and Company 85
Large-scale testing (Phase 3)Study completedNCT03412773
What this trial is testing

Tislelizumab Versus Sorafenib in Participants With Unresectable Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma (HCC)
BeiGene 684
Early research (Phase 1)Study completedNCT00005842
What this trial is testing

Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 24
Early research (Phase 1)WithdrawnNCT03217253
What this trial is testing

Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction

Who this might be right for
Ann Arbor Stage III B-Cell Non-Hodgkin LymphomaAnn Arbor Stage IV B-Cell Non-Hodgkin LymphomaMetastatic Malignant Solid Neoplasm+8 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT05733598
What this trial is testing

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

Who this might be right for
Hepatocellular CarcinomaBiliary Tract Cancer
Replimune Inc. 60
Testing effectiveness (Phase 2)Study completedNCT00019474
What this trial is testing

Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer

Who this might be right for
Extrahepatic Bile Duct CancerGastric CancerGastrointestinal Carcinoid Tumor+3 more
Montefiore Medical Center 60
Testing effectiveness (Phase 2)Looking for participantsNCT05440708
What this trial is testing

TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Tvardi Therapeutics, Incorporated 178
Not applicableStudy completedNCT00530010
What this trial is testing

Radiolabeled Glass Beads in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Who this might be right for
Liver Cancer
Northwestern University 500
Testing effectiveness (Phase 2)Study completedNCT04997850
What this trial is testing

The Safety and Efficacy of Transarterial Chemoembolization (TACE) + Lenvatinib + Programmed Cell Death Protein 1 (PD-1) Antibody of Advanced Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma Non-resectableTransarterial ChemoembolizationTyrosine Kinase Inhibitor+1 more
Xinrui Zhu，MD 142
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07291076
What this trial is testing

Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

Who this might be right for
Hepatocellular Carcinoma (HCC)
Bristol-Myers Squibb 129
Large-scale testing (Phase 3)UnknownNCT04687163
What this trial is testing

Sorafenib or Lenvatinib Plus HAIC of 130 mg/m² Oxaliplatin, and 5-fu vs Sorafenib or Lenvatinib Plus HAIC of 85mg/m² Oxaliplatin, and 5-fu for Unresectable Advanced HCC: a Randomised Phase 3 Trial

Who this might be right for
Hepatocellular Carcinoma
Sun Yat-sen University 400
Load More Results