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Results for “Hereditary Spastic Paraparesis”

42 trials

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Showing 20 of 42 results

Not applicableLooking for participantsNCT04875416
What this trial is testing

Phenotype, Genotype and Biomarkers 2

Who this might be right for
Amyotrophic Lateral SclerosisHereditary Spastic ParaplegiaPrimary Lateral Sclerosis+2 more
University of Miami 300
Not applicableLooking for participantsNCT06936163
What this trial is testing

A Prospective Cohort Study of Surgical Treatment for Foot Deformities in HSP

Who this might be right for
Hereditary Spastic Paraplegia
Shanghai 6th People's Hospital 100
Testing effectiveness (Phase 2)Study completedNCT04768166
What this trial is testing

Testing Miglustat Administration in Subjects With Spastic Paraplegia 11

Who this might be right for
Hereditary Spastic Paraparesis
IRCCS Fondazione Stella Maris 10
Not applicableEnded earlyNCT02859428
What this trial is testing

Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31

Who this might be right for
Hereditary Spastic Paraplegia
National Institute of Neurological Disorders and Stroke (NINDS) 51
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06948019
What this trial is testing

Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47)

Who this might be right for
HSPHereditary Spastic ParaplegiaHereditary Spastic Paraparesis+10 more
BlackfinBio Ltd 5
Early research (Phase 1)Study completedNCT06117020
What this trial is testing

Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals

Who this might be right for
Muscle SpasticityHypertonia, MuscleCerebral Palsy+5 more
Motric Bio 89
Not applicableLooking for participantsNCT06260982
What this trial is testing

Cognitive Disorders in Hereditary Spastic Paraplegia Type 4

Who this might be right for
Spastic Paraplegia
Central Hospital, Nancy, France 30
Large-scale testing (Phase 3)Looking for participantsNCT06692712
What this trial is testing

Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.

Who this might be right for
Hereditary Spastic Paraplegia Type 50
Elpida Therapeutics SPC 24
Not applicableStudy completedNCT05613114
What this trial is testing

Effect of Dalfampridine in Patients With Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic Paraplegia
European University of Lefke 8
Not applicableLooking for participantsNCT05848271
What this trial is testing

Natural History Study of Patients with HPDL Mutations

Who this might be right for
Mitochondrial EncephalomyopathiesHereditary Spastic ParaplegiaSpastic Paraplegia+4 more
University of California, San Diego 50
Not applicableLooking for participantsNCT06572046
What this trial is testing

STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic Strategies

Who this might be right for
Hereditary Spastic Paraplegia
IRCCS Fondazione Stella Maris 500
Not applicableStudy completedNCT00677768
What this trial is testing

Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)

Who this might be right for
Amyotrophic Lateral SclerosisLou Gehrig's DiseasePrimary Lateral Sclerosis+2 more
Massachusetts General Hospital 475
Testing effectiveness (Phase 2)Ended earlyNCT05394064
What this trial is testing

Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN)

Who this might be right for
AMNAMN Gene MutationX-ALD
SwanBio Therapeutics, Inc. 8
Not applicableStudy completedNCT05767268
What this trial is testing

Assessment of the Psychophysical State During Rehabilitation Treatment With Lokomat

Who this might be right for
Cerebral PalsyAcquired Brain InjuryHereditary Spastic Paraplegia
IRCCS Eugenio Medea 48
Not applicableStudy completedNCT02852278
What this trial is testing

A Patient Centric Motor Neuron Disease Activities of Daily Living Scale

Who this might be right for
Amyotrophic Lateral SclerosisProgressive Muscular AtrophyPrimary Lateral Sclerosis+1 more
University of South Florida 410
Testing effectiveness (Phase 2)UnknownNCT04101643
What this trial is testing

PCSK9 Inhibitor Treatment for Patients With SPG5

Who this might be right for
Hereditary Spastic Paraplegia Type 5
First Affiliated Hospital of Fujian Medical University 30
Not applicableLooking for participantsNCT06553976
What this trial is testing

Spastic Paraplegia - Centers of Excellence Research Network

Who this might be right for
Hereditary Spastic ParaplegiaPrimary Lateral SclerosisSPG4+6 more
Boston Children's Hospital 100
Not applicableEnrolling By InvitationNCT02327845
What this trial is testing

Phenotype, Genotype & Biomarkers in ALS and Related Disorders

Who this might be right for
Amyotrophic Lateral SclerosisFrontotemporal DementiaPrimary Lateral Sclerosis+3 more
University of Miami 700
Not applicableLooking for participantsNCT06742697
What this trial is testing

Flexibility, Resistance, Aerobic, Movement Execution Training in Adults With Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic Paraplegia
IRCCS Eugenio Medea 20
Not applicableStudy completedNCT03204773
What this trial is testing

Studying Non-motor Symptoms in HSP

Who this might be right for
SPG4
University Hospital Tuebingen 236
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