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Results for “Hereditary Spastic Paraplegia”

50 trials

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Showing 20 of 50 results

Early research (Phase 1)Study completedNCT06117020
What this trial is testing

Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals

Who this might be right for
Muscle SpasticityHypertonia, MuscleCerebral Palsy+5 more
Motric Bio 89
Not applicableLooking for participantsNCT06742697
What this trial is testing

Flexibility, Resistance, Aerobic, Movement Execution Training in Adults With Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic Paraplegia
IRCCS Eugenio Medea 20
Large-scale testing (Phase 3)Looking for participantsNCT06692712
What this trial is testing

Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.

Who this might be right for
Hereditary Spastic Paraplegia Type 50
Elpida Therapeutics SPC 24
Not applicableLooking for participantsNCT07090057
What this trial is testing

The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children

Who this might be right for
Idiopathic Toe WalkingCerebral PalsyHereditary Spastic Paraparesis+5 more
University of Alberta 42
Not applicableStudy completedNCT00136630
What this trial is testing

Natural History, Genetic Bases and Phenotype-genotype Correlations in Autosomal Dominant Spinocerebellar Degenerations

Who this might be right for
Spinocerebellar AtaxiasSpastic Paraplegias
Institut National de la Santé Et de la Recherche Médicale, France 175
Not applicableStudy completedNCT04256681
What this trial is testing

SNAP: Measurement of the Subjective Perception of the Symptom in Hereditary Spastic Paraparesis (HSP)

Who this might be right for
Hereditary Spastic Paraparesis
IRCCS Eugenio Medea 80
Not applicableLooking for participantsNCT01568658
What this trial is testing

Genetic and Physical Study of Childhood Nerve and Muscle Disorders

Who this might be right for
Muscular DystrophiesMuscle MyopathiesHereditary Spastic Paraplegias+2 more
National Institute of Neurological Disorders and Stroke (NINDS) 9,300
Testing effectiveness (Phase 2)Study completedNCT02314208
What this trial is testing

Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5

Who this might be right for
Spastic Paraplegia, Hereditary
Institut National de la Santé Et de la Recherche Médicale, France 12
Not applicableStudy completedNCT04912609
What this trial is testing

Trehalose Administration in Subjects With Spastic Paraplegia 11 (3AL-SPG11)

Who this might be right for
Hereditary Spastic ParaplegiaSpastic Paraplegia Type 11
IRCCS Fondazione Stella Maris 13
Not applicableStudy completedNCT05373082
What this trial is testing

Identification of Modifying Factors in Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic Paraplegia
Assistance Publique - Hôpitaux de Paris 311
Not applicableLooking for participantsNCT06260982
What this trial is testing

Cognitive Disorders in Hereditary Spastic Paraplegia Type 4

Who this might be right for
Spastic Paraplegia
Central Hospital, Nancy, France 30
Not applicableStudy completedNCT04180098
What this trial is testing

Improving Gait Adaptability in Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic ParaplegiaStrumpell Disease
Radboud University Medical Center 36
Not applicableLooking for participantsNCT04712812
What this trial is testing

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic ParaplegiaSPG47SPG50+8 more
Boston Children's Hospital 700
Not applicableStudy completedNCT05613114
What this trial is testing

Effect of Dalfampridine in Patients With Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic Paraplegia
European University of Lefke 8
Not applicableLooking for participantsNCT06573866
What this trial is testing

Enhancement of Quality of Work And Life

Who this might be right for
Parkinson DiseaseHereditary Spastic ParaparesisCerebellar Ataxia+2 more
Radboud University Medical Center 124
Not applicableStudy completedNCT05767268
What this trial is testing

Assessment of the Psychophysical State During Rehabilitation Treatment With Lokomat

Who this might be right for
Cerebral PalsyAcquired Brain InjuryHereditary Spastic Paraplegia
IRCCS Eugenio Medea 48
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06948019
What this trial is testing

Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47)

Who this might be right for
HSPHereditary Spastic ParaplegiaHereditary Spastic Paraparesis+10 more
BlackfinBio Ltd 5
Not applicableLooking for participantsNCT06728787
What this trial is testing

Robot-assisted Walking Treatment in Hereditary Spastic Paraplegia (HSP)

Who this might be right for
Hereditary Spastic Paraplegia
IRCCS Eugenio Medea 50
Large-scale testing (Phase 3)Study completedNCT02604186
What this trial is testing

Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic Paraplegia
University of Campinas, Brazil 55
Not applicableLooking for participantsNCT06553976
What this trial is testing

Spastic Paraplegia - Centers of Excellence Research Network

Who this might be right for
Hereditary Spastic ParaplegiaPrimary Lateral SclerosisSPG4+6 more
Boston Children's Hospital 100
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