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Results for “Heregulin”

27 trials

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Showing 20 of 27 results

Not applicableLooking for participantsNCT02820233
What this trial is testing

Studies of Neuregulin/ERBB Signaling in Human Heart

Who this might be right for
Heart DiseaseVascular DiseaseHeart Failure
Douglas B. Sawyer 80
Large-scale testing (Phase 3)Ended earlyNCT01439789
What this trial is testing

Study of Efficacy on NT-proBNP of Recombinant Human Neuregulin-1 in Chronic Heart Failure Patients

Who this might be right for
Chronic Heart Failure
Zensun Sci. & Tech. Co., Ltd. 146
Not applicableUnknownNCT01075373
What this trial is testing

A Neurobiological Study on Heterogeneity of Schizophrenia: Genetic Variations and Neurobiological Differentiations

Who this might be right for
Schizophrenia
National Taiwan University Hospital 360
Post-approval studies (Phase 4)UnknownNCT01078870
What this trial is testing

Trial for Antidepressant Treatment for Negative Symptom of Schizophrenia With NRG1 Risk Genotype

Who this might be right for
Schizophrenia
National Taiwan University Hospital 75
Early research (Phase 1)Study completedNCT04210375
What this trial is testing

Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)

Who this might be right for
Heart Failure With Reduced Ejection Fraction
Salubris Biotherapeutics Inc 14
Testing effectiveness (Phase 2)Looking for participantsNCT07221513
What this trial is testing

Study of JK07 in Patients With Heart Failure and WHO Group 2 Combined Post- and Pre-Capillary Pulmonary Hypertension

Who this might be right for
HFrEF - Heart Failure With Reduced Ejection FractionHFpEF - Heart Failure With Preserved Ejection FractionGroup 2 Pulmonary Hypertension
Salubris Biotherapeutics Inc 30
Testing effectiveness (Phase 2)Ended earlyNCT03241810
What this trial is testing

Phase 2 Trial of Seribantumab Plus Fulvestrant in Postmenopausal Women With Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Elevation Oncology 22
Testing effectiveness (Phase 2)Study completedNCT01251406
What this trial is testing

Efficacy and Safety of Human Neuregulin-1 to Treat Stable Chronic Heart Failure

Who this might be right for
Chronic Heart Failure
Zensun Sci. & Tech. Co., Ltd. 67
Early research (Phase 1)Study completedNCT00911898
What this trial is testing

MM-111 in Patients With Advanced, Refractory Her2 Amplified, Heregulin Positive Cancers

Who this might be right for
Her2 Amplified Solid TumorsMetastatic Breast Cancer
Merrimack Pharmaceuticals 20
Testing effectiveness (Phase 2)Ended earlyNCT02387216
What this trial is testing

MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC

Who this might be right for
Non-Small Cell Lung CancerNSCLCAdenocarcinoma+1 more
Elevation Oncology 153
Testing effectiveness (Phase 2)Active Not RecruitingNCT05057013
What this trial is testing

A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours

Who this might be right for
Bladder CancerTriple Negative Breast CancerCastration-resistant Prostate Cancer+11 more
Cancer Research UK 81
Early research (Phase 1)Study completedNCT01097460
What this trial is testing

MM-111 in Combination With Herceptin in Patients With Advanced Her2 Amplified, Heregulin Positive Breast Cancer

Who this might be right for
Breast Neoplasms
Merrimack Pharmaceuticals 16
Not applicableStudy completedNCT04391491
What this trial is testing

Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study

Who this might be right for
Heart Failure With Preserved Ejection FractionMicrovascular AnginaPulmonary Hypertension+1 more
I.M. Sechenov First Moscow State Medical University 100
Large-scale testing (Phase 3)Ended earlyNCT01541202
What this trial is testing

Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients

Who this might be right for
Chronic Heart Failure
Zensun Sci. & Tech. Co., Ltd. 679
Testing effectiveness (Phase 2)Study completedNCT02399137
What this trial is testing

MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Merrimack Pharmaceuticals 88
Not applicableNo Longer AvailableNCT05107193
What this trial is testing

Afatinib (GILOTRIF®) in Patients Suffering From Tumors Harboring Neuregulin 1 (NRG1) Gene Alterations (Specifically NRG1 Gene Fusion-positive Advanced Solid Tumors)

Who this might be right for
Solid Tumors
Boehringer Ingelheim
Early research (Phase 1)WithdrawnNCT05322616
What this trial is testing

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

Who this might be right for
Heart Failure With Preserved Ejection Fraction
Salubris Biotherapeutics Inc
Testing effectiveness (Phase 2)Ended earlyNCT04383210
What this trial is testing

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

Who this might be right for
Locally Advanced Solid TumorMetastatic Solid TumorPancreatic Cancer+14 more
Elevation Oncology 54
Large-scale testing (Phase 3)Looking for participantsNCT03388593
What this trial is testing

Survival Study of the Recombinant Human Neuregulin-1β in Subjects With Chronic Heart Failure.

Who this might be right for
Chronic Heart Failure
Zensun Sci. & Tech. Co., Ltd. 1,600
Large-scale testing (Phase 3)Ended earlyNCT01439893
What this trial is testing

Study of Efficacy on Cardiac Remodeling of Recombinant Human Neuregulin-1 in Stable Chronic Systolic Heart Failure Patients

Who this might be right for
Chronic Systolic Heart Failure
Zensun Sci. & Tech. Co., Ltd. 14
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