Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Heregulin”

28 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 28 results

Testing effectiveness (Phase 2)Ended earlyNCT03241810
What this trial is testing

Phase 2 Trial of Seribantumab Plus Fulvestrant in Postmenopausal Women With Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Elevation Oncology 22
Not applicableStudy completedNCT07806448
What this trial is testing

Impact of Asprosin and Neuregulin 4 on Metabolic Parameters, Anthropometric Indices and Body Composition After Laparoscopic Sleeve Gastrectomy

Who this might be right for
Bariatric Sleeve Gastrectomy
General Committee of Teaching Hospitals and Institutes, Egypt 160
Testing effectiveness (Phase 2)Active Not RecruitingNCT06369298
What this trial is testing

Study of JK07 in Patients With Chronic Heart Failure

Who this might be right for
Heart Failure With Reduced Ejection FractionHeart Failure With Preserved Ejection Fraction
Salubris Biotherapeutics Inc 282
Not applicableStudy completedNCT04391491
What this trial is testing

Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study

Who this might be right for
Heart Failure With Preserved Ejection FractionMicrovascular AnginaPulmonary Hypertension+1 more
I.M. Sechenov First Moscow State Medical University 100
Early research (Phase 1)WithdrawnNCT05322616
What this trial is testing

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

Who this might be right for
Heart Failure With Preserved Ejection Fraction
Salubris Biotherapeutics Inc
Not applicableLooking for participantsNCT02820233
What this trial is testing

Studies of Neuregulin/ERBB Signaling in Human Heart

Who this might be right for
Heart DiseaseVascular DiseaseHeart Failure
Douglas B. Sawyer 80
Testing effectiveness (Phase 2)Ended earlyNCT02387216
What this trial is testing

MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC

Who this might be right for
Non-Small Cell Lung CancerNSCLCAdenocarcinoma+1 more
Elevation Oncology 153
Testing effectiveness (Phase 2)Ended earlyNCT04383210
What this trial is testing

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

Who this might be right for
Locally Advanced Solid TumorMetastatic Solid TumorPancreatic Cancer+14 more
Elevation Oncology 54
Not applicableNo Longer AvailableNCT05107193
What this trial is testing

Afatinib (GILOTRIF®) in Patients Suffering From Tumors Harboring Neuregulin 1 (NRG1) Gene Alterations (Specifically NRG1 Gene Fusion-positive Advanced Solid Tumors)

Who this might be right for
Solid Tumors
Boehringer Ingelheim
Large-scale testing (Phase 3)Ended earlyNCT01541202
What this trial is testing

Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients

Who this might be right for
Chronic Heart Failure
Zensun Sci. & Tech. Co., Ltd. 679
Early research (Phase 1)Active Not RecruitingNCT05919537
What this trial is testing

Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation

Who this might be right for
Non-Small Cell Lung CancerPancreatic CancerLocally Advanced Solid Tumor+1 more
Hummingbird Bioscience 68
Not applicableUnknownNCT01075373
What this trial is testing

A Neurobiological Study on Heterogeneity of Schizophrenia: Genetic Variations and Neurobiological Differentiations

Who this might be right for
Schizophrenia
National Taiwan University Hospital 360
Post-approval studies (Phase 4)UnknownNCT01078870
What this trial is testing

Trial for Antidepressant Treatment for Negative Symptom of Schizophrenia With NRG1 Risk Genotype

Who this might be right for
Schizophrenia
National Taiwan University Hospital 75
Large-scale testing (Phase 3)Ended earlyNCT01439893
What this trial is testing

Study of Efficacy on Cardiac Remodeling of Recombinant Human Neuregulin-1 in Stable Chronic Systolic Heart Failure Patients

Who this might be right for
Chronic Systolic Heart Failure
Zensun Sci. & Tech. Co., Ltd. 14
Large-scale testing (Phase 3)Ended earlyNCT01439789
What this trial is testing

Study of Efficacy on NT-proBNP of Recombinant Human Neuregulin-1 in Chronic Heart Failure Patients

Who this might be right for
Chronic Heart Failure
Zensun Sci. & Tech. Co., Ltd. 146
Testing effectiveness (Phase 2)Active Not RecruitingNCT05057013
What this trial is testing

A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours

Who this might be right for
Bladder CancerTriple Negative Breast CancerCastration-resistant Prostate Cancer+11 more
Cancer Research UK 81
Early research (Phase 1)Study completedNCT01097460
What this trial is testing

MM-111 in Combination With Herceptin in Patients With Advanced Her2 Amplified, Heregulin Positive Breast Cancer

Who this might be right for
Breast Neoplasms
Merrimack Pharmaceuticals 16
Testing effectiveness (Phase 2)Study completedNCT01251406
What this trial is testing

Efficacy and Safety of Human Neuregulin-1 to Treat Stable Chronic Heart Failure

Who this might be right for
Chronic Heart Failure
Zensun Sci. & Tech. Co., Ltd. 67
Early research (Phase 1)Ended earlyNCT02538627
What this trial is testing

Phase 1 Combination Study of MM-151 With MM-121, MM-141, or Trametinib

Who this might be right for
Colorectal CancerNon-small Cell Lung CancerSquamous Cell Carcinoma of the Head and Neck
Merrimack Pharmaceuticals 5
Not applicableLooking for participantsNCT02664831
What this trial is testing

Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)

Who this might be right for
Cardiac ArrestInflammationObesity+1 more
MaineHealth 400
Next Page