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Results for “Heterozygous Familial”

99 trials

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Showing 20 of 99 results

Large-scale testing (Phase 3)Enrolling By InvitationNCT07102511
What this trial is testing

Study to Evaluate the Efficacy and Safety of Lerodalcibep in Children 6 to 17 Years, With Heterozygous FH

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
LIB Therapeutics LLC 150
Large-scale testing (Phase 3)Study completedNCT02107898
What this trial is testing

Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)

Who this might be right for
Hypercholesterolemia
Sanofi 216
Testing effectiveness (Phase 2)Study completedNCT04173793
What this trial is testing

PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Akeso 109
Large-scale testing (Phase 3)Study completedNCT00867165
What this trial is testing

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Who this might be right for
Primary Hypercholesterolemia
Organon and Co 138
Not applicableStudy completedNCT06389825
What this trial is testing

Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia.

Who this might be right for
Familial HypercholesterolemiaNutrition, HealthyCholesterol, Elevated
Laval University 11
Not applicableStudy completedNCT01109290
What this trial is testing

Characterization of Sweat Gland Function in Patients With Recessively Inherited Hypohidrotic Ectodermal Dysplasia

Who this might be right for
Hypohidrotic Ectodermal Dysplasia
University Hospital Erlangen 65
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Large-scale testing (Phase 3)Study completedNCT01524289
What this trial is testing

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

Who this might be right for
Hyperlipoproteinemia Type IIHypercholesterolemia, Familial
Merck Sharp & Dohme LLC 306
Not applicableStudy completedNCT03563547
What this trial is testing

Effects of Soy Protein on Cholesterol Levels in Children Affected With Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Austrian Academic Institute for Clinical Nutrition 34
Post-approval studies (Phase 4)Study completedNCT00145574
What this trial is testing

Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol

Who this might be right for
Hypercholesterolemia
Daiichi Sankyo 194
Large-scale testing (Phase 3)Study completedNCT00129402
What this trial is testing

Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)

Who this might be right for
Hypercholesterolemia
Organon and Co 248
Large-scale testing (Phase 3)Study completedNCT03397121
What this trial is testing

Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial HypercholesterolemiaElevated Cholesterol
The Medicines Company 482
Large-scale testing (Phase 3)Study completedNCT01475825
What this trial is testing

The Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol

Who this might be right for
HypercholesterolemiaHeterozygous Familial
Kastle Therapeutics, LLC 309
Large-scale testing (Phase 3)Study completedNCT02326220
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 62
Large-scale testing (Phase 3)Study completedNCT02392559
What this trial is testing

Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Amgen 158
Large-scale testing (Phase 3)Study completedNCT01824238
What this trial is testing

The Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 68
Large-scale testing (Phase 3)Study completedNCT00171236
What this trial is testing

Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial HypercholesterolemiaMixed Dyslipidemia
Novartis 84
Not applicableStudy completedNCT05218005
What this trial is testing

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein BFamilial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation+5 more
University of British Columbia 140
Not applicableLooking for participantsNCT07470723
What this trial is testing

The ORIGIN-FH Study

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)Homozygous Familial Hypercholesterolemia (HoFH)Familial Hypercholesterolemia
University of Wisconsin, Madison 70
Large-scale testing (Phase 3)Study completedNCT00136981
What this trial is testing

Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.

Who this might be right for
Hypercholesterolemia, FamilialHyperlipidemia
Pfizer 800
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