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Results for “Heterozygous Familial Hypercholesterolaemia”

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Showing 20 of 0 results

Very early researchNot Yet RecruitingNCT07353398
What this trial is testing

Early-phase Study of ART002g1 Injection in HeFH: Safety, Tolerability and Preliminary Efficacy

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 24
Early research (Phase 1)Looking for participantsNCT06164730
What this trial is testing

VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

Who this might be right for
Heterozygous Familial HypercholesterolemiaPremature Coronary Heart Disease
Verve Therapeutics, Inc. 85
Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Not applicableUnknownNCT04837638
What this trial is testing

Diet Quality and Coronary Artery Calcification in Adults With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia, FamilialCalcification; HeartDiet Habit
Laval University 258
Testing effectiveness (Phase 2)Study completedNCT01266876
What this trial is testing

Study of the Safety and Efficacy of REGN727/SAR236553 in Patients With HeFH Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 77
Large-scale testing (Phase 3)Study completedNCT00654602
What this trial is testing

48-wk Open Label Phase IIIb to Evaluate Efficacy and Safety

Who this might be right for
Dyslipidaemia
AstraZeneca 1,500
Testing effectiveness (Phase 2)Study completedNCT04173793
What this trial is testing

PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Akeso 109
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Post-approval studies (Phase 4)Ended earlyNCT03694197
What this trial is testing

Long Term Safety Study of PRALUENT

Who this might be right for
Heterozygous Familial HypercholesterolemiaNon-familial Hypercholesterolemia
Regeneron Pharmaceuticals 1,389
Large-scale testing (Phase 3)UnknownNCT04759534
What this trial is testing

Application of PCSK9 Inhibitors in Patients With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Efficacy and SafetyHeterozygous Familial HypercholesterolemiaPCSK9
Shenzhen People's Hospital 20
Large-scale testing (Phase 3)Study completedNCT03397121
What this trial is testing

Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial HypercholesterolemiaElevated Cholesterol
The Medicines Company 482
Not applicableEnrolling By InvitationNCT06112327
What this trial is testing

Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease

Who this might be right for
Atherosclerotic Cardiovascular DiseaseHeterozygous Familial HypercholesterolemiaHypercholesterolemia
Verve Therapeutics, Inc. 116
Large-scale testing (Phase 3)Study completedNCT03337308
What this trial is testing

A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin Therapy

Who this might be right for
Hyperlipidemias
Esperion Therapeutics, Inc. 382
Large-scale testing (Phase 3)Study completedNCT00171236
What this trial is testing

Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial HypercholesterolemiaMixed Dyslipidemia
Novartis 84
Not applicableStudy completedNCT03501875
What this trial is testing

Study of Coronary Calcification in Subjects With Autosomal Dominant Familial Hypercholesterolemia Heterozygous

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Assistance Publique - Hôpitaux de Paris 270
Early research (Phase 1)Looking for participantsNCT07491172
What this trial is testing

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Who this might be right for
CardiovascularMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG 90
Large-scale testing (Phase 3)Study completedNCT02107898
What this trial is testing

Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)

Who this might be right for
Hypercholesterolemia
Sanofi 216
Large-scale testing (Phase 3)Looking for participantsNCT07465263
What this trial is testing

Evaluate the SYH2053 Injection in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 135
Not applicableUnknownNCT03310671
What this trial is testing

Aortic Stenosis in Subjects With Heterozygous Familial Hypercholesterolemia on Prolonged Treatment With Statins

Who this might be right for
Aortic StenosisArteriosclerosisFamilial Hypercholesterolemia+1 more
Instituto Aragones de Ciencias de la Salud 900
Large-scale testing (Phase 3)Looking for participantsNCT06568471
What this trial is testing

A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia

Who this might be right for
HypercholesterolemiaDyslipidemiasPrimary Hypercholesterolemia+4 more
Hasten Biopharmaceutical Co., Ltd. 210
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