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Results for “High Grade CNS Tumors”

378 trials

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Showing 20 of 378 results

Testing effectiveness (Phase 2)Study completedNCT00028795
What this trial is testing

Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Children's Oncology Group 170
Early research (Phase 1)Study completedNCT00019071
What this trial is testing

Chemotherapy Followed by Radiation Therapy in Treating Patients With Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
National Cancer Institute (NCI)
Early research (Phase 1)WithdrawnNCT00458744
What this trial is testing

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Children's Oncology Group
Not applicableLooking for participantsNCT06312644
What this trial is testing

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Who this might be right for
Ultomiris-exposed Pregnant/ PostpartumPregnancyParoxysmal Nocturnal Hemoglobinuria (PNH)+3 more
Alexion Pharmaceuticals, Inc. 75
Testing effectiveness (Phase 2)Ended earlyNCT01836549
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAstrocytoma, Grade II+6 more
Pediatric Brain Tumor Consortium 43
Early research (Phase 1)Looking for participantsNCT04099797
What this trial is testing

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

Who this might be right for
Diffuse Intrinsic Pontine GliomaHigh Grade GliomaEmbryonal Tumor+1 more
Baylor College of Medicine 37
Not applicableTemporarily pausedNCT04031469
What this trial is testing

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

Who this might be right for
Gut MicrobiomeGastrointestinal MicrobiomeAutism+77 more
ProgenaBiome 1,000
Testing effectiveness (Phase 2)Study completedNCT02596828
What this trial is testing

Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma

Who this might be right for
Pineoblastoma
University of Regensburg 4
Testing effectiveness (Phase 2)Ended earlyNCT03352427
What this trial is testing

Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations

Who this might be right for
GliomaHigh Grade GliomaPontine Tumors
University of Michigan Rogel Cancer Center 3
Very early researchLooking for participantsNCT06072586
What this trial is testing

BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions

Who this might be right for
High Grade GliomaGlioblastoma
St. Joseph's Hospital and Medical Center, Phoenix 82
Early research (Phase 1)Looking for participantsNCT05686798
What this trial is testing

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Who this might be right for
Malignant Glioma of BrainAstrocytomaMalignant Astrocytoma+6 more
Henry Ford Health System 18
Early research (Phase 1)Study completedNCT01644955
What this trial is testing

Carboplatin in Treating Patients With Recurrent High-Grade Gliomas

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic OligodendrogliomaRecurrent Adult Brain Tumor
James Elder 10
Not applicableStudy completedNCT04132843
What this trial is testing

Novel MRI Techniques for the Characterization and Treatment Assessment of High Grade Brain Lesions

Who this might be right for
Brain NeoplasmLymphomaMetastatic Malignant Neoplasm in the Brain+1 more
M.D. Anderson Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT01574092
What this trial is testing

Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas

Who this might be right for
Pediatric High Risk Gliomas
Hospital Sant Joan de Deu 39
Very early researchEnded earlyNCT02279992
What this trial is testing

Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases

Who this might be right for
GliomaBrain NeoplasmsBrain Metastasis
Cedars-Sinai Medical Center 7
Early research (Phase 1)Looking for participantsNCT06624371
What this trial is testing

Atovaquone Combined With Radiation in Children With Malignant Brain Tumors

Who this might be right for
High-grade GliomaMedulloblastomaDiffuse Intrinsic Pontine Glioma+1 more
Emory University 18
Testing effectiveness (Phase 2)UnknownNCT00313521
What this trial is testing

Thiotepa and Radiation Therapy in Treating Young Patients With Newly Diagnosed Malignant Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Children's Cancer and Leukaemia Group 30
Testing effectiveness (Phase 2)WithdrawnNCT04482933
What this trial is testing

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

Who this might be right for
NeoplasmsHigh Grade GliomaGlioblastoma Multiforme+5 more
Pediatric Brain Tumor Consortium
Not applicableStudy completedNCT02849171
What this trial is testing

Assessing 11C-Choline (11C-CH) PET to Distinguish True Tumor Progression From Pseudoprogression in High-grade Gliomas

Who this might be right for
Brain Cancer
Memorial Sloan Kettering Cancer Center 8
Very early researchActive Not RecruitingNCT02933736
What this trial is testing

Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients

Who this might be right for
Glioblastoma MultiformeMeningioma
Nader Sanai 48
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