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Results for “High Grade Neuroendocrine Cancer”

82 trials

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Showing 20 of 82 results

Testing effectiveness (Phase 2)Study completedNCT00004922
What this trial is testing

Irinotecan in Treating Patients With Advanced Neuroendocrine Tumors

Who this might be right for
Carcinoma of Unknown PrimaryNeuroendocrine CarcinomaNeuroendocrine Carcinoma of the Skin
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)WithdrawnNCT04759846
What this trial is testing

Hepatic Impairment Study of Encorafenib in Combination With Binimetinib in BRAF Melanoma

Who this might be right for
BRAF V600 MutationUnresectable MelanomaMetastatic Melanoma+1 more
Pierre Fabre Medicament
Testing effectiveness (Phase 2)WithdrawnNCT02763761
What this trial is testing

An Investigational Study of Infliximab With Prednisone or Methylprednisolone Versus Prednisone Combination Treatment in Immune Related or Severe Diarrhea in Patients Treated With Yervoy and/or Opdivo

Who this might be right for
Renal Cell CarcinomaMelanomaLung Cancer
Bristol-Myers Squibb
Testing effectiveness (Phase 2)Active Not RecruitingNCT04802174
What this trial is testing

Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High-Grade Neuroendocrine Cancers

Who this might be right for
SCLCSmall Cell CancerAdvanced Solid Tumor+1 more
National Cancer Institute (NCI) 37
Testing effectiveness (Phase 2)WithdrawnNCT03901378
What this trial is testing

Pembrolizumab With Chemotherapy in Metastatic or Unresectable High Grade Gastroenteropancreatic or Lung Neuroendocrine Carcinoma

Who this might be right for
Neuroendocrine CarcinomaLarge Cell Neuroendocrine Carcinoma of the LungHigh Grade Neuroendocrine Carcinoma, Any Site
Ochsner Health System
Testing effectiveness (Phase 2)Study completedNCT03352934
What this trial is testing

Avelumab Treatment in Patients With Neuroendocrine Carcinomas (NEC G3) Progressive After Chemotherapy

Who this might be right for
Cancer
Johannes Gutenberg University Mainz 60
Testing effectiveness (Phase 2)Looking for participantsNCT06161532
What this trial is testing

Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...

Who this might be right for
Small Cell Carcinoma of the BladderSmall Cell Carcinoma of the Urinary TractSquamous Cell Carcinoma of the Bladder+5 more
National Cancer Institute (NCI)
Large-scale testing (Phase 3)Study completedNCT00002641
What this trial is testing

Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma

Who this might be right for
Endometrial CancerKidney CancerOvarian Cancer+2 more
European Organisation for Research and Treatment of Cancer - EORTC 350
Early research (Phase 1)Study completedNCT03517488
What this trial is testing

XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Who this might be right for
MelanomaBreast CarcinomaHepatocellular Carcinoma+25 more
Xencor, Inc. 150
Testing effectiveness (Phase 2)Ended earlyNCT05420636
What this trial is testing

Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET

Who this might be right for
Small-cell Lung CancerNeuroendocrine Carcinoma
Fox Chase Cancer Center 20
Large-scale testing (Phase 3)Looking for participantsNCT06784752
What this trial is testing

Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET

Who this might be right for
Somatostatin Receptor Positive (SSTR+)Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET)
Novartis Pharmaceuticals 240
Early research (Phase 1)Looking for participantsNCT06889493
What this trial is testing

SVV-001 With Nivolumab and Ipilimumab in Patients With Poorly Differentiated Neuroendocrine Carcinomas (NEC) or Well-Differentiated High-Grade Neuroendocrine Tumors (NET)

Who this might be right for
Neuroendocrine CarcinomaNeuroendocrine Tumors
Peter Hosein, MD 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT04701307
What this trial is testing

Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas

Who this might be right for
Lung Small Cell CarcinomaNeuroendocrine CarcinomaStage III Lung Cancer AJCC v8+3 more
M.D. Anderson Cancer Center 48
Early research (Phase 1)Looking for participantsNCT05039801
What this trial is testing

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Who this might be right for
Advanced Endometrial CarcinomaAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Malignant Solid Neoplasm+35 more
M.D. Anderson Cancer Center 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT06521567
What this trial is testing

Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Who this might be right for
MelanomaHodgkin LymphomaHigh and Low Grade Glioma+9 more
GlaxoSmithKline 83
Post-approval studies (Phase 4)Study completedNCT04074460
What this trial is testing

Volatile Anaesthesia and Perioperative Outcomes Related to Cancer Feasibility Study

Who this might be right for
Cancer, BreastCancer ColorectalCancer Prostate+3 more
Peter MacCallum Cancer Centre, Australia 169
Not applicableEnded earlyNCT03698162
What this trial is testing

Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases

Who this might be right for
Brain MetastasesGlioma of BrainBrain Tumor+1 more
University of Southern California 15
Testing effectiveness (Phase 2)Looking for participantsNCT06926634
What this trial is testing

Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)

Who this might be right for
High Grade Neuroendocrine Neoplasms
Washington University School of Medicine 32
Very early researchLooking for participantsNCT07132645
What this trial is testing

An Investigational Scan ([68Ga] Ga-FAPI-04 PET/CT) for the Imaging of Patients With High-Grade Neuroendocrine Cancer

Who this might be right for
Neuroendocrine Tumor
University of Michigan Rogel Cancer Center 30
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
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