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Results for “High Grade Serous Adenocarcinoma of Ovary”

38 trials

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Showing 20 of 38 results

Early research (Phase 1)Active Not RecruitingNCT05858736
What this trial is testing

Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors

Who this might be right for
MelanomaNon Small Cell Lung CancerHead and Neck Squamous Cell Carcinoma+14 more
OncoC4, Inc. 18
Early research (Phase 1)Active Not RecruitingNCT06084416
What this trial is testing

Sovilnesib in Subjects With Ovarian Cancer

Who this might be right for
High Grade Serous Adenocarcinoma of OvaryFallopian Tube CancerPrimary Peritoneal Carcinoma+1 more
Volastra Therapeutics, Inc. 120
Testing effectiveness (Phase 2)Looking for participantsNCT05329532
What this trial is testing

Modi-1 Moditope in Breast, Head and Neck, Ovarian, or Renal Cancer

Who this might be right for
Triple Negative Breast CancerRenal Cell CancerHigh Grade Ovarian Serous Adenocarcinoma+1 more
Scancell Ltd 168
Testing effectiveness (Phase 2)WithdrawnNCT06393751
What this trial is testing

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Who this might be right for
Platinum-Refractory Fallopian Tube CarcinomaPlatinum-Refractory Ovarian CarcinomaPlatinum-Refractory Primary Peritoneal Carcinoma+20 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT05902988
What this trial is testing

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid TumorHigh Grade Serous Adenocarcinoma of OvarySquamous Non-small-cell Lung Cancer+7 more
Volastra Therapeutics, Inc. 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT04034927
What this trial is testing

Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer

Who this might be right for
Fallopian Tube Endometrioid TumorFallopian Tube High Grade Serous AdenocarcinomaMalignant Ovarian Endometrioid Tumor+11 more
National Cancer Institute (NCI) 61
Not applicableLooking for participantsNCT04794322
What this trial is testing

Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer

Who this might be right for
Ovarian NeoplasmsOvarian Epithelial CarcinomaFallopian Tube Neoplasms+12 more
Massachusetts General Hospital 250
Testing effectiveness (Phase 2)UnknownNCT06161272
What this trial is testing

Fluzoparib With or Without Apatinib in Platinum-sensitive Relapsed Ovarian Cancer Previously Treated With PARPi

Who this might be right for
Ovarian CancerHigh Grade Serous Adenocarcinoma of OvaryPrimary Peritoneal Carcinoma+1 more
Guangxi Medical University 80
Testing effectiveness (Phase 2)Looking for participantsNCT05080556
What this trial is testing

Adaptive ChemoTherapy for Ovarian Cancer in Patients With Replased Platinum-sensitive High Grade Serous or High Grade Endometrioid Ovarian Cancer

Who this might be right for
Ovarian CancerRelapsed Ovarian CancerFallopian Tube Cancer+4 more
University College, London 80
Not applicableLooking for participantsNCT06883487
What this trial is testing

Exploratory Study on HER2 Detection Method and Positive Threshold for High-grade Serous Adenocarcinoma of the Ovary

Who this might be right for
Exploring HER2 Positive Diagnostic Criteria in High-grade Serous Ovarian CancerObserving the Effectiveness of Targeted HER2 ADC Drugs
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 144
Testing effectiveness (Phase 2)Active Not RecruitingNCT05114421
What this trial is testing

Pembrolizumab and Lenvatinib for the Treatment of Serous Ovarian Cancer Patients

Who this might be right for
High Grade Fallopian Tube Serous AdenocarcinomaHigh Grade Ovarian Serous AdenocarcinomaPeritoneal High Grade Serous Adenocarcinoma+3 more
M.D. Anderson Cancer Center 30
Very early researchStudy completedNCT02316834
What this trial is testing

Talazoparib in Determining Genetic Effects on Disease Response in Patients With Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Fallopian Tube Serous AdenocarcinomaHigh Grade Ovarian Serous AdenocarcinomaOvarian Mass+16 more
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)Looking for participantsNCT05961124
What this trial is testing

Alternative Dosing Of Niraparib To Decrease Dose Interruption In First Line Maintenance Treatment For Ovarian Cancer

Who this might be right for
Ovarian CancerStage III Ovarian CancerStage IV Ovarian Cancer+1 more
Sunnybrook Health Sciences Centre 40
Not applicableNot Yet RecruitingNCT06553742
What this trial is testing

High Definition Profiling of Ovarian Cancer Ascites

Who this might be right for
Ovarian CancerHigh Grade Ovarian Serous AdenocarcinomaAscites
European Institute of Oncology 50
Early research (Phase 1)Ended earlyNCT03608618
What this trial is testing

Intraperitoneal MCY-M11 (Mesothelin-targeting CAR) for Treatment of Advanced Ovarian Cancer and Peritoneal Mesothelioma

Who this might be right for
Peritoneal MesotheliomaFallopian Tube AdenocarcinomaAdenocarcinoma of the Ovary+1 more
MaxCyte, Inc. 14
Testing effectiveness (Phase 2)Active Not RecruitingNCT03907852
What this trial is testing

Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer

Who this might be right for
MesotheliomaMesothelioma, MalignantMesothelioma; Pleura+8 more
TCR2 Therapeutics 57
Testing effectiveness (Phase 2)Active Not RecruitingNCT05446298
What this trial is testing

ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer

Who this might be right for
Ovarian CancerHigh Grade Serous Adenocarcinoma of OvaryPrimary Peritoneal Carcinoma+1 more
OncoC4, Inc. 58
Testing effectiveness (Phase 2)Active Not RecruitingNCT01116648
What this trial is testing

Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer

Who this might be right for
Fallopian Tube CarcinomaOvarian Endometrioid AdenocarcinomaOvarian High Grade Serous Adenocarcinoma+4 more
National Cancer Institute (NCI) 155
Early research (Phase 1)Ended earlyNCT03924245
What this trial is testing

Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers

Who this might be right for
Fallopian Tube CancerFallopian Tube CarcinosarcomaFallopian Tube Clear Cell Adenocarcinoma+10 more
Vanderbilt-Ingram Cancer Center 3
Very early researchActive Not RecruitingNCT03943173
What this trial is testing

Olaparib in Treating Patients With Newly Diagnosed BRCA-Mutant Ovarian, Primary Peritoneal, or Fallopian Cancer Before Surgery

Who this might be right for
BRCA-Mutated Ovarian CarcinomaBRCA1 Gene MutationBRCA2 Gene Mutation+28 more
M.D. Anderson Cancer Center 15
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