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Results for “High Grade Serous Carcinoma”

125 trials

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Showing 20 of 125 results

Early research (Phase 1)Active Not RecruitingNCT02627443
What this trial is testing

Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Who this might be right for
Metastatic Fallopian Tube CarcinomaMetastatic Ovarian CarcinomaMetastatic Primary Peritoneal Carcinoma+9 more
National Cancer Institute (NCI) 35
Testing effectiveness (Phase 2)Ended earlyNCT01972516
What this trial is testing

Tivozanib As Maintenance Therapy In GYN

Who this might be right for
Ovarian CancerFallopian Tube CancerPrimary Peritoneal Carcinoma
Dana-Farber Cancer Institute 4
Early research (Phase 1)Active Not RecruitingNCT05858736
What this trial is testing

Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors

Who this might be right for
MelanomaNon Small Cell Lung CancerHead and Neck Squamous Cell Carcinoma+14 more
OncoC4, Inc. 18
Not applicableWithdrawnNCT05390021
What this trial is testing

PET/MRI in Endometrial Cancer

Who this might be right for
Cytoreductive SurgeryGrade 3 Endometrial Endometrioid AdenocarcinomaHigh Grade Serous Carcinoma+2 more
Massachusetts General Hospital
Not applicableStudy completedNCT01836484
What this trial is testing

Diagnostic Accuracy of MRI, DWI MRI, FDG-PET/CT and FEC PET/CT in the Detection of Lymph Node Metastases in Surgically Staged Endometrial and Cervical Carcinoma

Who this might be right for
Surgically Staged Endometrial and Cervical CarcinomaCervical Cancer: Invasive Disease, FIGO Stage 1B1 or HigherEndometrial Cancer+3 more
Barts & The London NHS Trust 162
Early research (Phase 1)Active Not RecruitingNCT06084416
What this trial is testing

Sovilnesib in Subjects With Ovarian Cancer

Who this might be right for
High Grade Serous Adenocarcinoma of OvaryFallopian Tube CancerPrimary Peritoneal Carcinoma+1 more
Volastra Therapeutics, Inc. 120
Testing effectiveness (Phase 2)Ended earlyNCT03311334
What this trial is testing

DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Urothelial CarcinomaPrimary Peritoneal Cancer+3 more
Sumitomo Pharma America, Inc. 47
Testing effectiveness (Phase 2)Looking for participantsNCT05329532
What this trial is testing

Modi-1 Moditope in Breast, Head and Neck, Ovarian, or Renal Cancer

Who this might be right for
Triple Negative Breast CancerRenal Cell CancerHigh Grade Ovarian Serous Adenocarcinoma+1 more
Scancell Ltd 168
Early research (Phase 1)Active Not RecruitingNCT05358639
What this trial is testing

Combination of Olaparib and Navitoclax in Women with HGSC and TNBC

Who this might be right for
High Grade Serous CarcinomaTriple Negative Breast CancerOvarian Cancer
Sunnybrook Health Sciences Centre 36
Testing effectiveness (Phase 2)WithdrawnNCT06393751
What this trial is testing

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Who this might be right for
Platinum-Refractory Fallopian Tube CarcinomaPlatinum-Refractory Ovarian CarcinomaPlatinum-Refractory Primary Peritoneal Carcinoma+20 more
National Cancer Institute (NCI)
Not applicableLooking for participantsNCT06404671
What this trial is testing

Timing of Surgery After Neoadjuvant Chemotherapy for Advanced Ovarian Cancer

Who this might be right for
Ovarian Epithelial Cancer
Alexandria University 250
Early research (Phase 1)Looking for participantsNCT05950464
What this trial is testing

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

Who this might be right for
Recurrent Endometrial CarcinomaRecurrent Endometrial Clear Cell AdenocarcinomaRecurrent Endometrial Endometrioid Adenocarcinoma+6 more
National Cancer Institute (NCI) 60
Early research (Phase 1)Active Not RecruitingNCT05827614
What this trial is testing

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Who this might be right for
Triple Negative Breast Cancer (TNBC)High Grade Serous Ovarian CarcinomaHigh Grade Endometrial Carcinoma+9 more
Boundless Bio 85
Early research (Phase 1)Looking for participantsNCT04389632
What this trial is testing

Sigvotatug Vedotin in Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckHER2 Negative Breast Neoplasms+9 more
Seagen, a wholly owned subsidiary of Pfizer 1,006
Not applicableLooking for participantsNCT07169396
What this trial is testing

Identifying Genetic Targets in Gynecological Tumors

Who this might be right for
Ovarian Cancer
Azienda USL Reggio Emilia - IRCCS 180
Testing effectiveness (Phase 2)Looking for participantsNCT05902988
What this trial is testing

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid TumorHigh Grade Serous Adenocarcinoma of OvarySquamous Non-small-cell Lung Cancer+7 more
Volastra Therapeutics, Inc. 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT04034927
What this trial is testing

Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer

Who this might be right for
Fallopian Tube Endometrioid TumorFallopian Tube High Grade Serous AdenocarcinomaMalignant Ovarian Endometrioid Tumor+11 more
National Cancer Institute (NCI) 61
Testing effectiveness (Phase 2)Looking for participantsNCT05998135
What this trial is testing

Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer

Who this might be right for
Ovarian High Grade Serous AdenocarcinomaPlatinum-Resistant Ovarian Carcinoma
Emory University 28
Not applicableLooking for participantsNCT04794322
What this trial is testing

Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer

Who this might be right for
Ovarian NeoplasmsOvarian Epithelial CarcinomaFallopian Tube Neoplasms+12 more
Massachusetts General Hospital 250
Not applicableUnknownNCT03794115
What this trial is testing

Immune Repertoire of Ovarian HGSC

Who this might be right for
Ovarian High Grade Serous CarcinomaImmune RepertoireT Lymphocyte Receptor+1 more
Lei Li 40
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