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Results for “High Grade Serous Ovarian Cancer”

182 trials

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Showing 20 of 182 results

Early research (Phase 1)Active Not RecruitingNCT02627443
What this trial is testing

Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Who this might be right for
Metastatic Fallopian Tube CarcinomaMetastatic Ovarian CarcinomaMetastatic Primary Peritoneal Carcinoma+9 more
National Cancer Institute (NCI) 35
Testing effectiveness (Phase 2)Ended earlyNCT01972516
What this trial is testing

Tivozanib As Maintenance Therapy In GYN

Who this might be right for
Ovarian CancerFallopian Tube CancerPrimary Peritoneal Carcinoma
Dana-Farber Cancer Institute 4
Early research (Phase 1)Ended earlyNCT01227941
What this trial is testing

MK-4827 in Combination With Pegylated Liposomal Doxorubicin in Participants With Advanced Solid Tumors and Ovarian Cancer (MK-4827-011)

Who this might be right for
Ovarian Cancer
Tesaro, Inc. 6
Early research (Phase 1)Study completedNCT01623349
What this trial is testing

Phase I Study of the Oral PI3kinase Inhibitor BKM120 or BYL719 and the Oral PARP Inhibitor Olaparib in Patients With Recurrent Triple Negative Breast Cancer or High Grade Serous Ovarian Cancer

Who this might be right for
Ovarian CancerBreast Cancer
Dana-Farber Cancer Institute 118
Early research (Phase 1)Active Not RecruitingNCT06084416
What this trial is testing

Sovilnesib in Subjects With Ovarian Cancer

Who this might be right for
High Grade Serous Adenocarcinoma of OvaryFallopian Tube CancerPrimary Peritoneal Carcinoma+1 more
Volastra Therapeutics, Inc. 120
Testing effectiveness (Phase 2)Ended earlyNCT03311334
What this trial is testing

DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Urothelial CarcinomaPrimary Peritoneal Cancer+3 more
Sumitomo Pharma America, Inc. 47
Testing effectiveness (Phase 2)Looking for participantsNCT05329532
What this trial is testing

Modi-1 Moditope in Breast, Head and Neck, Ovarian, or Renal Cancer

Who this might be right for
Triple Negative Breast CancerRenal Cell CancerHigh Grade Ovarian Serous Adenocarcinoma+1 more
Scancell Ltd 168
Early research (Phase 1)Active Not RecruitingNCT05358639
What this trial is testing

Combination of Olaparib and Navitoclax in Women with HGSC and TNBC

Who this might be right for
High Grade Serous CarcinomaTriple Negative Breast CancerOvarian Cancer
Sunnybrook Health Sciences Centre 36
Testing effectiveness (Phase 2)Study completedNCT02354586
What this trial is testing

Niraparib in Patients With Ovarian Cancer Who Have Received Three or Four Previous Chemotherapy Regimens

Who this might be right for
Ovarian NeoplasmsOvarian Cancer
Tesaro, Inc. 463
Early research (Phase 1)Ended earlyNCT04893551
What this trial is testing

Tilvestamab (BGB149) in Relapsed, Platinum-resistant, High-grade Serous Ovarian Cancer (HGSOC) Participants

Who this might be right for
Ovarian Neoplasms
BerGenBio ASA 16
Testing effectiveness (Phase 2)WithdrawnNCT06393751
What this trial is testing

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Who this might be right for
Platinum-Refractory Fallopian Tube CarcinomaPlatinum-Refractory Ovarian CarcinomaPlatinum-Refractory Primary Peritoneal Carcinoma+20 more
National Cancer Institute (NCI)
Not applicableLooking for participantsNCT06404671
What this trial is testing

Timing of Surgery After Neoadjuvant Chemotherapy for Advanced Ovarian Cancer

Who this might be right for
Ovarian Epithelial Cancer
Alexandria University 250
Early research (Phase 1)Looking for participantsNCT05950464
What this trial is testing

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

Who this might be right for
Recurrent Endometrial CarcinomaRecurrent Endometrial Clear Cell AdenocarcinomaRecurrent Endometrial Endometrioid Adenocarcinoma+6 more
National Cancer Institute (NCI) 60
Testing effectiveness (Phase 2)Study completedNCT02983799
What this trial is testing

Olaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumor Status

Who this might be right for
Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity
AstraZeneca 272
Early research (Phase 1)Active Not RecruitingNCT05827614
What this trial is testing

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Who this might be right for
Triple Negative Breast Cancer (TNBC)High Grade Serous Ovarian CarcinomaHigh Grade Endometrial Carcinoma+9 more
Boundless Bio 85
Not applicableLooking for participantsNCT03419689
What this trial is testing

Study Looking at Biomarkers in Ovarian Cancer

Who this might be right for
Gynecologic Cancer
University Health Network, Toronto 510
Early research (Phase 1)Looking for participantsNCT04389632
What this trial is testing

Sigvotatug Vedotin in Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckHER2 Negative Breast Neoplasms+9 more
Seagen, a wholly owned subsidiary of Pfizer 1,006
Not applicableLooking for participantsNCT07169396
What this trial is testing

Identifying Genetic Targets in Gynecological Tumors

Who this might be right for
Ovarian Cancer
Azienda USL Reggio Emilia - IRCCS 180
Testing effectiveness (Phase 2)Looking for participantsNCT05902988
What this trial is testing

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid TumorHigh Grade Serous Adenocarcinoma of OvarySquamous Non-small-cell Lung Cancer+7 more
Volastra Therapeutics, Inc. 200
Not applicableUnknownNCT05069818
What this trial is testing

Variance of HRD From Paired Ovarian Cancer

Who this might be right for
Ovarian CancerHRDPlatinum-sensitive Ovarian Cancer
Xiaoxiang Chen 50
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