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Results for “High Grade Urothelial Carcinoma”

28 trials

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Showing 20 of 28 results

Large-scale testing (Phase 3)Looking for participantsNCT04628767
What this trial is testing

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Who this might be right for
Renal Pelvis and Ureter Urothelial Carcinoma
National Cancer Institute (NCI) 131
Testing effectiveness (Phase 2)Active Not RecruitingNCT02834013
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Who this might be right for
Acinar Cell CarcinomaAdenoid Cystic CarcinomaAdrenal Cortical Carcinoma+91 more
National Cancer Institute (NCI) 798
Testing effectiveness (Phase 2)Study completedNCT01687244
What this trial is testing

Intravesical Administration of rAd-IFN/Syn3 in Patients With BCG-Refractory or Relapsed Bladder Cancer

Who this might be right for
Superficial Bladder Cancer
FKD Therapies Oy 40
Testing effectiveness (Phase 2)Study completedNCT02015104
What this trial is testing

Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG

Who this might be right for
Bladder Cancer
National Cancer Institute (NCI) 32
Early research (Phase 1)Active Not RecruitingNCT05768347
What this trial is testing

Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC

Who this might be right for
Urothelial CarcinomaNon-Invasive Bladder Urothelial Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 9
Testing effectiveness (Phase 2)Study completedNCT01261728
What this trial is testing

Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy in Patients With High-Grade Upper Tract Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Memorial Sloan Kettering Cancer Center 57
Testing effectiveness (Phase 2)Active Not RecruitingNCT03333616
What this trial is testing

Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors

Who this might be right for
Genitourinary CancerAdrenocortical CarcinomaNon-urothelial Bladder+5 more
Dana-Farber Cancer Institute 100
Testing effectiveness (Phase 2)Looking for participantsNCT05656235
What this trial is testing

Renal Retention in High Grade Upper Tract Urothelial Cancer

Who this might be right for
High Grade Urothelial CarcinomaBladder CancerUrothelial Carcinoma Bladder
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 20
Testing effectiveness (Phase 2)Looking for participantsNCT05868265
What this trial is testing

Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract

Who this might be right for
Urothelial Carcinoma
Memorial Sloan Kettering Cancer Center 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT04739800
What this trial is testing

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Who this might be right for
Fallopian Tube Mucinous AdenocarcinomaOvarian Seromucinous CarcinomaPlatinum-Refractory Fallopian Tube Carcinoma+47 more
National Cancer Institute (NCI) 120
Large-scale testing (Phase 3)Not Yet RecruitingNCT07480356
What this trial is testing

Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer

Who this might be right for
Bladder (Urothelial, Transitional Cell) CancerNon-Muscle Invasive Bladder CarcinomaNon-muscle Invasive Bladder Cancer With Carcinoma in Situ
Protara Therapeutics 284
Early research (Phase 1)Looking for participantsNCT06451497
What this trial is testing

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

Who this might be right for
Non Small Cell Lung CancerHead and Neck Squamous Cell CarcinomaPancreas Adenocarcinoma+8 more
Zumutor Biologics Inc. 100
Early research (Phase 1)Active Not RecruitingNCT04092270
What this trial is testing

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

Who this might be right for
Endometrial High Grade Endometrioid AdenocarcinomaFallopian Tube Clear Cell AdenocarcinomaFallopian Tube Endometrioid Adenocarcinoma+26 more
National Cancer Institute (NCI) 54
Large-scale testing (Phase 3)Active Not RecruitingNCT03091660
What this trial is testing

S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer

Who this might be right for
Stage 0 Bladder Urothelial CarcinomaStage 0is Bladder Urothelial CarcinomaStage I Bladder Urothelial Carcinoma
SWOG Cancer Research Network 1,000
Testing effectiveness (Phase 2)Ended earlyNCT03311334
What this trial is testing

DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Urothelial CarcinomaPrimary Peritoneal Cancer+3 more
Sumitomo Pharma America, Inc. 47
Not applicableLooking for participantsNCT05463796
What this trial is testing

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Who this might be right for
Cancer RiskCancer Predisposition SyndromeHereditary Cancer Prediction+28 more
Dana-Farber Cancer Institute 5,000
Testing effectiveness (Phase 2)Looking for participantsNCT07322263
What this trial is testing

Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

Who this might be right for
Bladder CancerNon-Muscle Invasive Bladder Cancer (NMIBC)Urothelial Carcinoma+8 more
Michael A. O'Donnell 174
Early research (Phase 1)Study completedNCT03517488
What this trial is testing

XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Who this might be right for
MelanomaBreast CarcinomaHepatocellular Carcinoma+25 more
Xencor, Inc. 150
Testing effectiveness (Phase 2)Study completedNCT02412670
What this trial is testing

Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer

Who this might be right for
High Grade Upper Tract Urothelial Carcinoma
ECOG-ACRIN Cancer Research Group 36
Early research (Phase 1)Study completedNCT02020707
What this trial is testing

Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers

Who this might be right for
Cervical AdenocarcinomaCervical AdenosarcomaCervical Adenosquamous Carcinoma+45 more
Mayo Clinic 43
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