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Results for “High Grade Urothelial Carcinoma”

29 trials

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Showing 20 of 29 results

Early research (Phase 1)Study completedNCT02020707
What this trial is testing

Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers

Who this might be right for
Cervical AdenocarcinomaCervical AdenosarcomaCervical Adenosquamous Carcinoma+45 more
Mayo Clinic 43
Testing effectiveness (Phase 2)Looking for participantsNCT05656235
What this trial is testing

Renal Retention in High Grade Upper Tract Urothelial Cancer

Who this might be right for
High Grade Urothelial CarcinomaBladder CancerUrothelial Carcinoma Bladder
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 20
Large-scale testing (Phase 3)Active Not RecruitingNCT03091660
What this trial is testing

S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer

Who this might be right for
Stage 0 Bladder Urothelial CarcinomaStage 0is Bladder Urothelial CarcinomaStage I Bladder Urothelial Carcinoma
SWOG Cancer Research Network 1,000
Early research (Phase 1)Active Not RecruitingNCT05768347
What this trial is testing

Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC

Who this might be right for
Urothelial CarcinomaNon-Invasive Bladder Urothelial Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 9
Large-scale testing (Phase 3)Looking for participantsNCT04628767
What this trial is testing

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Who this might be right for
Renal Pelvis and Ureter Urothelial Carcinoma
National Cancer Institute (NCI) 131
Testing effectiveness (Phase 2)Looking for participantsNCT06161532
What this trial is testing

Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...

Who this might be right for
Small Cell Carcinoma of the BladderSmall Cell Carcinoma of the Urinary TractSquamous Cell Carcinoma of the Bladder+5 more
National Cancer Institute (NCI)
Early research (Phase 1)Active Not RecruitingNCT04092270
What this trial is testing

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

Who this might be right for
Endometrial High Grade Endometrioid AdenocarcinomaFallopian Tube Clear Cell AdenocarcinomaFallopian Tube Endometrioid Adenocarcinoma+26 more
National Cancer Institute (NCI) 55
Testing effectiveness (Phase 2)Study completedNCT02015104
What this trial is testing

Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG

Who this might be right for
Bladder Cancer
National Cancer Institute (NCI) 32
Testing effectiveness (Phase 2)Looking for participantsNCT06770582
What this trial is testing

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Who this might be right for
Non-Muscle Invasive Bladder Urothelial CarcinomaRecurrent Non-Muscle Invasive Bladder Urothelial CarcinomaStage I Bladder Cancer AJCC v8
National Cancer Institute (NCI) 160
Not applicableLooking for participantsNCT05463796
What this trial is testing

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Who this might be right for
Cancer RiskCancer Predisposition SyndromeHereditary Cancer Prediction+28 more
Dana-Farber Cancer Institute 5,000
Early research (Phase 1)Looking for participantsNCT06451497
What this trial is testing

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

Who this might be right for
Non Small Cell Lung CancerHead and Neck Squamous Cell CarcinomaPancreas Adenocarcinoma+8 more
Zumutor Biologics Inc. 100
Testing effectiveness (Phase 2)Study completedNCT01687244
What this trial is testing

Intravesical Administration of rAd-IFN/Syn3 in Patients With BCG-Refractory or Relapsed Bladder Cancer

Who this might be right for
Superficial Bladder Cancer
FKD Therapies Oy 40
Very early researchEnded earlyNCT03266900
What this trial is testing

A Superiority Trial to Compare Re-resection of High-grade T1 Bladder Urothelial Carcinoma to no Re-resection for Improving Progression Free Survival

Who this might be right for
Bladder CancerBladder Urothelial Carcinoma
University Health Network, Toronto 2
Testing effectiveness (Phase 2)Study completedNCT02412670
What this trial is testing

Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer

Who this might be right for
High Grade Upper Tract Urothelial Carcinoma
ECOG-ACRIN Cancer Research Group 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT03504163
What this trial is testing

Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]

Who this might be right for
Bladder Cancer
Memorial Sloan Kettering Cancer Center 45
Testing effectiveness (Phase 2)Ended earlyNCT03311334
What this trial is testing

DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Urothelial CarcinomaPrimary Peritoneal Cancer+3 more
Sumitomo Pharma America, Inc. 47
Testing effectiveness (Phase 2)Active Not RecruitingNCT04739800
What this trial is testing

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Who this might be right for
Fallopian Tube Mucinous AdenocarcinomaOvarian Seromucinous CarcinomaPlatinum-Refractory Fallopian Tube Carcinoma+47 more
National Cancer Institute (NCI) 120
Testing effectiveness (Phase 2)Study completedNCT02876861
What this trial is testing

Neoadjuvant Chemotherapy Versus Surgery Alone in Patients With High-Grade UTUC

Who this might be right for
High-Grade Upper Tract Urothelial Carcinoma
Xiangya Hospital of Central South University 74
Early research (Phase 1)Study completedNCT03517488
What this trial is testing

XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Who this might be right for
MelanomaBreast CarcinomaHepatocellular Carcinoma+25 more
Xencor, Inc. 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT05868265
What this trial is testing

Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract

Who this might be right for
Urothelial Carcinoma
Memorial Sloan Kettering Cancer Center 9
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