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Results for “High Risk Acute Myeloid Leukemia”

643 trials

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Showing 20 of 643 results

Early research (Phase 1)Looking for participantsNCT02203903
What this trial is testing

Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies

Who this might be right for
Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS
Catherine Bollard 50
Testing effectiveness (Phase 2)Study completedNCT03531918
What this trial is testing

Gemtuzumab Ozogamicin With G-CSF, Cladribine, Cytarabine & Mitoxantrone for Untreated AML & High-Grade Myeloid Neoplasm

Who this might be right for
Acute Myeloid Leukemia
Fred Hutchinson Cancer Center 66
Testing effectiveness (Phase 2)Active Not RecruitingNCT04262843
What this trial is testing

Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaHigh Risk Myelodysplastic Syndrome+1 more
City of Hope Medical Center 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT01522976
What this trial is testing

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Who this might be right for
Chronic Myelomonocytic LeukemiaChronic Myelomonocytic Leukemia-1Chronic Myelomonocytic Leukemia-2+4 more
National Cancer Institute (NCI) 282
Early research (Phase 1)UnknownNCT05457010
What this trial is testing

Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Arcellx, Inc. 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06754540
What this trial is testing

Azacitidine Combined with Donor Lymphocyte Infusion for Acute Myeloid Leukemia Post-transplant Relapse Prevention.

Who this might be right for
Acute Myeloid Leukemia (AML)Relapse
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 51
Early research (Phase 1)Looking for participantsNCT06810583
What this trial is testing

A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia

Who this might be right for
LeukemiaAcute Myeloid LeukemiaLymphoblastic Leukemia in Children
St. Jude Children's Research Hospital 29
Testing effectiveness (Phase 2)Looking for participantsNCT07410494
What this trial is testing

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
CancerBreast CancerNon-Small Cell Lung Cancer (NSCLC)+10 more
Essen Biotech 85
Testing effectiveness (Phase 2)Ended earlyNCT01465386
What this trial is testing

Bortezomib in Treating Patients With High-Risk Acute Myeloid Leukemia in Remission

Who this might be right for
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Minimally Differentiated Myeloid Leukemia (M0)Adult Acute Myeloblastic Leukemia Without Maturation (M1)+9 more
Fred Hutchinson Cancer Center 6
Early research (Phase 1)Study completedNCT00569283
What this trial is testing

Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant

Who this might be right for
Cancer
Asan Medical Center 18
Early research (Phase 1)Ended earlyNCT02319369
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
Daiichi Sankyo 74
Testing effectiveness (Phase 2)Looking for participantsNCT04049539
What this trial is testing

Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction

Who this might be right for
Blasts More Than 5 Percent of Bone Marrow Nucleated CellsPersistent DiseaseRefractory Acute Myeloid Leukemia
Ohio State University Comprehensive Cancer Center 28
Early research (Phase 1)Study completedNCT00401739
What this trial is testing

Safety, Tolerability and Pharmacokinetics of CSL360 in the Treatment of Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia (AML)
CSL Limited 40
Early research (Phase 1)Study completedNCT00070551
What this trial is testing

GTI-2040 and High-Dose Cytarabine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+3 more
National Cancer Institute (NCI) 51
Testing effectiveness (Phase 2)Study completedNCT01869114
What this trial is testing

Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+7 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 57
Testing effectiveness (Phase 2)Study completedNCT00083187
What this trial is testing

VNP40101M in Treating Patients With Acute Myelogenous Leukemia or High-Risk Myelodysplasia

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Neoplasms
Vion Pharmaceuticals 230
Testing effectiveness (Phase 2)Study completedNCT00553202
What this trial is testing

Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 158
Not applicableLooking for participantsNCT06710418
What this trial is testing

Evaluating the Effects of Hemoglobin Threshold-specific Packed Red Blood Cell Transfusions on Quality of Life and Functional Outcomes in Patients With High-grade Myeloid Neoplasms, Acute Myeloid Leukemia, or B Acute Lymphoblastic Lymphoma/Leukemia

Who this might be right for
Acute Myeloid LeukemiaB Acute Lymphoblastic LeukemiaB Lymphoblastic Lymphoma+1 more
University of Washington 50
Early research (Phase 1)UnknownNCT00769613
What this trial is testing

Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections

Who this might be right for
Cancer
Milton S. Hershey Medical Center 20
Testing effectiveness (Phase 2)Looking for participantsNCT05732103
What this trial is testing

CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Chordia Therapeutics, Inc. 225
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