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Results for “High Risk Acute Myeloid Leukemia”

632 trials

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Showing 20 of 632 results

Early research (Phase 1)Ended earlyNCT02641002
What this trial is testing

CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Celgene 28
Testing effectiveness (Phase 2)UnknownNCT01423175
What this trial is testing

ClAraC or FLAMSA Followed by Stem Cell Transplantation to Treat High Risk AML or Advanced MDS

Who this might be right for
Acute Myeloid LeukemiaMDS
Hannover Medical School 60
Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Early research (Phase 1)Looking for participantsNCT05292664
What this trial is testing

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Who this might be right for
Myelodysplastic Syndromes, de NovoMyelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously Treated+8 more
Andrew E. Place, MD 30
Post-approval studies (Phase 4)UnknownNCT02024308
What this trial is testing

AML1-ETO Acute Myeloid Leukemia With Fludarabine and Cytarabine Chemotherapy

Who this might be right for
Acute Myeloid LeukemiaAML1-ETO Fusion Protein Expression
Changhai Hospital 62
Testing effectiveness (Phase 2)WithdrawnNCT01652014
What this trial is testing

Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in Remission+51 more
University of Medicine and Dentistry of New Jersey
Testing effectiveness (Phase 2)Study completedNCT01839916
What this trial is testing

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)+61 more
University of Chicago 77
Large-scale testing (Phase 3)Study completedNCT00495287
What this trial is testing

A Remission Induction Therapy and Risk-oriented Postremission Strategy for Adult Acute Myelogenous Leukemia (AML)

Who this might be right for
Acute Myelogenous Leukemia
Northern Italy Leukemia Group 573
Testing effectiveness (Phase 2)Study completedNCT03030612
What this trial is testing

ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
OncoVerity, Inc. 38
Early research (Phase 1)Ended earlyNCT00852709
What this trial is testing

Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemias

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid LeukemiaMyeloproliferative Disorders+7 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 35
Early research (Phase 1)Study completedNCT00006246
What this trial is testing

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorLeukemia+4 more
Pediatric Brain Tumor Consortium 28
Testing effectiveness (Phase 2)Looking for participantsNCT04049539
What this trial is testing

Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction

Who this might be right for
Blasts More Than 5 Percent of Bone Marrow Nucleated CellsPersistent DiseaseRefractory Acute Myeloid Leukemia
Ohio State University Comprehensive Cancer Center 28
Early research (Phase 1)Study completedNCT02649764
What this trial is testing

Prexasertib (LY2606368), Cytarabine, and Fludarabine in Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Chronic Myelomonocytic LeukemiaRecurrent Acute Myeloid LeukemiaRecurrent High Risk Myelodysplastic Syndrome+2 more
M.D. Anderson Cancer Center 15
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Early research (Phase 1)Study completedNCT05775406
What this trial is testing

Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors

Who this might be right for
Myeloid MalignanciesAcute Lymphocytic LeukemiaLymphomas+1 more
Kymera Therapeutics, Inc. 52
Large-scale testing (Phase 3)Ended earlyNCT00038805
What this trial is testing

Nonmyeloablative Preparative Regimen Using Mylotarg for Patients With High Risk Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myeloid Leukemia (CML) and Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 3
Large-scale testing (Phase 3)Ended earlyNCT04326764
What this trial is testing

Panobinostat Maintenance After HSCT fo High-risk AML and MDS

Who this might be right for
Acute Myeloid Leukaemia (AML)Myelodysplastic Syndromes (MDS)
Goethe University 52
Testing effectiveness (Phase 2)Ended earlyNCT03404193
What this trial is testing

Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlastic Plasmacytoid Dendritic Cell Neoplasm+12 more
M.D. Anderson Cancer Center 235
Testing effectiveness (Phase 2)Looking for participantsNCT06717958
What this trial is testing

Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation

Who this might be right for
AMLMDS
Technische Universität Dresden 76
Testing effectiveness (Phase 2)UnknownNCT00126321
What this trial is testing

Cladribine, Cytarabine and Idarubicin in Patients With Relapsed Acute Myelocytic Leukemia (AML)

Who this might be right for
Leukemia, Myelocytic, Acute
University Hospital, Bonn 50
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