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Results for “High Risk Hematologic Disorders”

1,667 trials

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Showing 20 of 1,667 results

Large-scale testing (Phase 3)Looking for participantsNCT07393282
What this trial is testing

Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)

Who this might be right for
High Risk Smoldering Multiple Myeloma (HR-SMM)
Regeneron Pharmaceuticals 270
Testing effectiveness (Phase 2)Ended earlyNCT01625741
What this trial is testing

Phase II Study of High-Dose Rituximab in High-Risk Chronic Lymphocytic Leukemia Patients in Suboptimal Response After Induction Immunochemotherapy

Who this might be right for
Chronic Lymphocytic Leukemia
Cliniques universitaires Saint-Luc- Université Catholique de Louvain 6
Early research (Phase 1)Ended earlyNCT01801046
What this trial is testing

Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

Who this might be right for
Adult Acute Megakaryoblastic Leukemia (M7)Adult Acute Monoblastic Leukemia (M5a)Adult Acute Monocytic Leukemia (M5b)+24 more
University of Southern California 10
Large-scale testing (Phase 3)Study completedNCT01259856
What this trial is testing

Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET)

Who this might be right for
High Risk Polycythemia VeraHigh Risk Essential Thrombocythemia
Ronald Hoffman 168
Testing effectiveness (Phase 2)Study completedNCT00553202
What this trial is testing

Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 158
Early research (Phase 1)Study completedNCT00875745
What this trial is testing

Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteLeukemia, Promyelocytic, AcuteMyelodysplastic Syndromes
Indiana University 15
Large-scale testing (Phase 3)Study completedNCT00022737
What this trial is testing

Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia

Who this might be right for
Childhood Acute Lymphoblastic Leukemia in RemissionRecurrent Childhood Acute Lymphoblastic Leukemia
National Cancer Institute (NCI) 220
Testing effectiveness (Phase 2)Active Not RecruitingNCT04933539
What this trial is testing

Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

Who this might be right for
Multiple Myeloma
National Cancer Institute (NCI) 14
Testing effectiveness (Phase 2)Study completedNCT03788291
What this trial is testing

Acalabrutinib and High Frequency Low Dose Subcutaneous Rituximab in Patients With Previously Untreated Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)
University of Rochester 39
Testing effectiveness (Phase 2)Active Not RecruitingNCT06098313
What this trial is testing

HCT With PTCy in Higher-risk MDS

Who this might be right for
Patients With MDS, Acute Myeloid Leukemia (AML) Evolving From MDS, and Chronic Myelomonocytic Leukemia (CMML)
Asan Medical Center 113
Testing effectiveness (Phase 2)Active Not RecruitingNCT00869232
What this trial is testing

UARK 2008-02 A Trial for High-risk Myeloma Evaluating Accelerating and Sustaining Complete Remission

Who this might be right for
Multiple Myeloma
University of Arkansas 90
Testing effectiveness (Phase 2)Ended earlyNCT00655395
What this trial is testing

Treatment of Elderly Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic (MD) Syndrome With Laromustine and Infusional Cytarabine

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)
Viron Therapeutics Inc 25
Large-scale testing (Phase 3)Looking for participantsNCT05197192
What this trial is testing

A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL

Who this might be right for
Chronic Lymphocytic Leukemia
German CLL Study Group 202
Post-approval studies (Phase 4)Study completedNCT00171899
What this trial is testing

Study Comparing Standard Dose and High-dose Imatinib Mesylate in Patients With Chronic Phase Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia (CML)

Who this might be right for
Chronic Myelogenous Leukemia
Novartis Pharmaceuticals 80
Early research (Phase 1)Study completedNCT00641030
What this trial is testing

Clofarabine and High-Dose Melphalan Followed by Donor Stem Cell Transplant in Patients With Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Myelodysplastic Syndromes

Who this might be right for
LeukemiaMyelodysplastic Syndromes
City of Hope Medical Center 20
Not applicableWithdrawnNCT01051544
What this trial is testing

Study of First TIME Immunotolerance Induction in Severe Hemophilia A Patients With Inhibitor at High Risk of Failure: Comparison With FVIII Concentrates With or Without Von Willebrand Factor - RES.I.S.T. Naive

Who this might be right for
Severe Hemophilia A
City of Hope Medical Center
Large-scale testing (Phase 3)Study completedNCT02288741
What this trial is testing

Tandem Melphalan and Autolog. SCT in MM Patients 60 to 70 Years of Age With and Without Induction Chemotherapy

Who this might be right for
Multiple Myeloma
WiSP Wissenschaftlicher Service Pharma GmbH 549
Large-scale testing (Phase 3)Study completedNCT00551928
What this trial is testing

Lenalidomide Melphalan and Prednisone Versus High Dose Melphalan in Newly Diagnosed Multiple Myeloma Patients

Who this might be right for
Multiple MyelomaNewly Diagnosed Patients
Fondazione EMN Italy Onlus 402
Testing effectiveness (Phase 2)Study completedNCT00050154
What this trial is testing

Study of Tipifarnib in Patients With High-Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Myelodysplastic Syndrome
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 82
Testing effectiveness (Phase 2)UnknownNCT03188172
What this trial is testing

MUK Nine b: OPTIMUM Treatment Protocol

Who this might be right for
Multiple Myeloma
University of Leeds 95
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