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Results for “High Risk Hematologic Malignancies”

1,374 trials

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Showing 20 of 1,374 results

Testing effectiveness (Phase 2)UnknownNCT04935580
What this trial is testing

Study of FasT CAR-T GC012F Injection in High Risk TE NDMM Patients

Who this might be right for
Multiple Myeloma
Shanghai Changzheng Hospital 20
Testing effectiveness (Phase 2)UnknownNCT03598179
What this trial is testing

XLCART001 Treatment in Relapsed/Refractory/High-risk B-cell Malignancy Subjects

Who this might be right for
Lymphoma, B-CellLeukemia, B-cell
The First Affiliated Hospital with Nanjing Medical University 10
Large-scale testing (Phase 3)Looking for participantsNCT02416388
What this trial is testing

Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR

Who this might be right for
Acute Myeloid Leukemia (AML)
University Hospital, Angers 3,100
Testing effectiveness (Phase 2)Study completedNCT04103879
What this trial is testing

US Study of UM171-Expanded CB in Patients With High Risk Leukemia/Myelodysplasia

Who this might be right for
High Risk Hematological MalignancyCord Blood Transplant
ExCellThera inc. 30
Testing effectiveness (Phase 2)Looking for participantsNCT04588922
What this trial is testing

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

Who this might be right for
Hematologic Malignancies
Sellas Life Sciences Group 160
Not applicableLooking for participantsNCT06710418
What this trial is testing

Evaluating the Effects of Hemoglobin Threshold-specific Packed Red Blood Cell Transfusions on Quality of Life and Functional Outcomes in Patients With High-grade Myeloid Neoplasms, Acute Myeloid Leukemia, or B Acute Lymphoblastic Lymphoma/Leukemia

Who this might be right for
Acute Myeloid LeukemiaB Acute Lymphoblastic LeukemiaB Lymphoblastic Lymphoma+1 more
University of Washington 50
Early research (Phase 1)Study completedNCT01300572
What this trial is testing

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Who this might be right for
Chronic Myelomonocytic LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Lymphoblastic Leukemia+3 more
Fred Hutchinson Cancer Center 16
Early research (Phase 1)Ended earlyNCT02641002
What this trial is testing

CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Celgene 28
Early research (Phase 1)Looking for participantsNCT07573111
What this trial is testing

Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

Who this might be right for
Acute LeukemiaMyelodysplastic Syndrome
Laguna Biotherapeutics, Inc. 12
Testing effectiveness (Phase 2)Study completedNCT00968071
What this trial is testing

Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia and High-risk Myelodysplastic Syndrome

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
M.D. Anderson Cancer Center 71
Testing effectiveness (Phase 2)Study completedNCT00096122
What this trial is testing

Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+20 more
National Cancer Institute (NCI) 95
Large-scale testing (Phase 3)UnknownNCT02270307
What this trial is testing

MSC and Cyclophosphamide for Acute Graft-Versus-Host Disease (aGVHD) Prophylaxis

Who this might be right for
LeukemiaMultiple Myeloma
National Research Center for Hematology, Russia 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT04998786
What this trial is testing

A Multi-center Open-label Phase 2 Study of Ixazomib, Iberdomide and Dexamethasone in Elderly Patients With Multiple Myeloma at First Relapse."

Who this might be right for
Multiple Myeloma at First Relapse
Nantes University Hospital 75
Testing effectiveness (Phase 2)Looking for participantsNCT06100237
What this trial is testing

Teclistamab in Combination With Daratumumab for High-Risk Smoldering Myeloma: A Clinical and Correlative Phase 2 Immuno-Oncology Study (the REVIVE Study)

Who this might be right for
Multiple Myeloma
Carl Ola Landgren, MD, PhD 50
Early research (Phase 1)Study completedNCT03263637
What this trial is testing

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Who this might be right for
Relapsed or Refractory Haematological Malignancies IncludingAcute Myeloid LeukemiaAcute Lymphocytic Leukemia+8 more
AstraZeneca 44
Testing effectiveness (Phase 2)Study completedNCT00064311
What this trial is testing

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+9 more
National Institutes of Health Clinical Center (CC)
Early research (Phase 1)Ended earlyNCT02716805
What this trial is testing

Phase 1 Study of Tremelimumab, Durvalumab, High-dose Chemotherapy, + Autologous Stem Cell Transplant

Who this might be right for
Multiple Myeloma
Ludwig Institute for Cancer Research 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT03709719
What this trial is testing

Blinatumomab in High-risk B-cell Precursor Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia, Adult B-Cell
Assistance Publique - Hôpitaux de Paris 95
Testing effectiveness (Phase 2)Active Not RecruitingNCT03625037
What this trial is testing

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

Who this might be right for
DLBCLHigh-grade B-cell Lymphoma (HGBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+6 more
Genmab 666
Testing effectiveness (Phase 2)Study completedNCT01168219
What this trial is testing

Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaAdult Acute Megakaryoblastic LeukemiaAdult Acute Monoblastic Leukemia+17 more
National Cancer Institute (NCI) 68
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