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Results for “High Risk Hematologic Malignancy”

1,374 trials

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Showing 20 of 1,374 results

Testing effectiveness (Phase 2)Looking for participantsNCT06807606
What this trial is testing

Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell Transplantation

Who this might be right for
Hematologic Malignancies
M.D. Anderson Cancer Center 35
Early research (Phase 1)Study completedNCT01149915
What this trial is testing

Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+3 more
Threshold Pharmaceuticals 40
Early research (Phase 1)Study completedNCT03602235
What this trial is testing

High Dose Ascorbic Acid for Plasma Cell Disorders

Who this might be right for
Multiple Myeloma
Christopher Strouse 6
Testing effectiveness (Phase 2)Study completedNCT00003335
What this trial is testing

Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+2 more
Case Comprehensive Cancer Center 44
Early research (Phase 1)Active Not RecruitingNCT05878184
What this trial is testing

Study Evaluating SC291 in Subjects With r/r B-cell Malignancies (ARDENT)

Who this might be right for
Non Hodgkin LymphomaChronic Lymphocytic Leukemia
Sana Biotechnology 16
Testing effectiveness (Phase 2)WithdrawnNCT04044209
What this trial is testing

The IDH1 Inhibitor AG-120 in Combination With the Checkpoint Blockade Inhibitor, Nivolumab, for Patients With IDH1 Mutated Relapsed/Refractory AML and High Risk MDS

Who this might be right for
Myelodysplastic SyndromesAcute Myeloid Leukemia
Yale University
Not applicableStudy completedNCT01653106
What this trial is testing

Randomized Trial of Cryotherapy Duration Prior to High Dose Melphalan in Myeloma Patients

Who this might be right for
Refractory Multiple MyelomaStage I Multiple MyelomaStage II Multiple Myeloma+1 more
Ohio State University Comprehensive Cancer Center 148
Testing effectiveness (Phase 2)Study completedNCT00065143
What this trial is testing

Clofarabine Plus Cytarabine in Patients With Previously Untreated Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

Who this might be right for
Leukemia, MyeloidMyelodysplastic Syndromes
M.D. Anderson Cancer Center 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT01885689
What this trial is testing

Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia

Who this might be right for
Adult Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Myeloid Leukemia in Remission+4 more
City of Hope Medical Center
Early research (Phase 1)Study completedNCT02485535
What this trial is testing

Selinexor in Treating Patients With Intermediate- and High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome After Transplant

Who this might be right for
Acute Myeloid Leukemiade Novo Myelodysplastic SyndromeMyelodysplastic Syndrome+2 more
University of Chicago 12
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07562568
What this trial is testing

SHR2554/AZA + Overlapped TBF for High-risk/Relapsed Leukemia/MDS

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMDS+4 more
The First Affiliated Hospital of Soochow University 160
Not applicableStudy completedNCT03234335
What this trial is testing

High Dose Therapy Followed by Autologous Transplantation for Myeloma Patients With Severe Renal Impairment

Who this might be right for
Multiple MyelomaRenal Failure
Centre Hospitalier Universitaire de Saint Etienne 50
Early research (Phase 1)Looking for participantsNCT07249840
What this trial is testing

Ropeginterferon for High Risk JAK2 Clonal Hematopoiesis

Who this might be right for
JAK2 Mutation
Brigham and Women's Hospital 12
Testing effectiveness (Phase 2)Study completedNCT00475150
What this trial is testing

Cediranib Maleate in Treating Patients With Relapsed, Refractory, or Untreated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+8 more
National Cancer Institute (NCI) 39
Not applicableLooking for participantsNCT07285668
What this trial is testing

Prophylactic TCRaB+ and CD19+ Depleted Donor Lymphocyte Infusion After Allogeneic Stem Cell Transplant in High-Risk Patients With Hematologic Malignancies

Who this might be right for
Hematologic Malignancies
University of Wisconsin, Madison 38
Testing effectiveness (Phase 2)Study completedNCT02169791
What this trial is testing

Nonmyeloablative Haploidentical Transplant Followed by MLN9708

Who this might be right for
Acute LeukemiaChronic LeukemiaMyelodysplastic Syndrome+2 more
Northside Hospital, Inc. 29
Testing effectiveness (Phase 2)Study completedNCT02125318
What this trial is testing

Anagrelide Controlled Release (GALE-401) in Patients With High Platelet Counts Due to Bone Marrow Disorders

Who this might be right for
ThrombocytosisMyeloproliferative Neoplasms
Galena Biopharma, Inc. 18
Large-scale testing (Phase 3)Looking for participantsNCT06588413
What this trial is testing

Olanzapine 2.5 vs 5 mg in Quadruplet Nausea/Vomiting Prophylaxis Before High-Dose Melphalan

Who this might be right for
Multiple MyelomaAutologous Stem Cell Transplantation
Augusta University 172
Early research (Phase 1)Ended earlyNCT00376519
What this trial is testing

Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+3 more
Masonic Cancer Center, University of Minnesota 3
Testing effectiveness (Phase 2)Study completedNCT02771197
What this trial is testing

Lymphodepletion and Anti-PD-1 Blockade to Reduce Relapse in AML Patient Not Eligible for Transplant

Who this might be right for
Acute Myeloid Leukemia
Northside Hospital, Inc. 20
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