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Results for “High Risk Myelodysplastic Syndrome”

570 trials

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Showing 20 of 570 results

Early research (Phase 1)Ended earlyNCT02641002
What this trial is testing

CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Celgene 28
Testing effectiveness (Phase 2)UnknownNCT01423175
What this trial is testing

ClAraC or FLAMSA Followed by Stem Cell Transplantation to Treat High Risk AML or Advanced MDS

Who this might be right for
Acute Myeloid LeukemiaMDS
Hannover Medical School 60
Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Early research (Phase 1)Looking for participantsNCT05292664
What this trial is testing

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Who this might be right for
Myelodysplastic Syndromes, de NovoMyelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously Treated+8 more
Andrew E. Place, MD 30
Testing effectiveness (Phase 2)WithdrawnNCT01652014
What this trial is testing

Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in Remission+51 more
University of Medicine and Dentistry of New Jersey
Not applicableUnknownNCT01252784
What this trial is testing

Reduced-intensity Conditioning Allogeneic Hematopoietic Cell Transplantation

Who this might be right for
Myelodysplastic Syndrome
Cooperative Study Group A for Hematology 20
Testing effectiveness (Phase 2)Study completedNCT01839916
What this trial is testing

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)+61 more
University of Chicago 77
Testing effectiveness (Phase 2)Study completedNCT03030612
What this trial is testing

ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
OncoVerity, Inc. 38
Early research (Phase 1)Ended earlyNCT00852709
What this trial is testing

Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemias

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid LeukemiaMyeloproliferative Disorders+7 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 35
Testing effectiveness (Phase 2)Study completedNCT00004464
What this trial is testing

Study of High Dose Cyclophosphamide in Patients With Severe Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Aplastic AnemiaParoxysmal Hemoglobinuria, Nocturnal
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 69
Early research (Phase 1)Study completedNCT02649764
What this trial is testing

Prexasertib (LY2606368), Cytarabine, and Fludarabine in Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Chronic Myelomonocytic LeukemiaRecurrent Acute Myeloid LeukemiaRecurrent High Risk Myelodysplastic Syndrome+2 more
M.D. Anderson Cancer Center 15
Testing effectiveness (Phase 2)UnknownNCT06109064
What this trial is testing

Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With Higher-risk MDS

Who this might be right for
Myelodysplastic Syndromes
Anhui Provincial Hospital 14
Large-scale testing (Phase 3)Ended earlyNCT00038805
What this trial is testing

Nonmyeloablative Preparative Regimen Using Mylotarg for Patients With High Risk Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myeloid Leukemia (CML) and Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 3
Large-scale testing (Phase 3)Ended earlyNCT04326764
What this trial is testing

Panobinostat Maintenance After HSCT fo High-risk AML and MDS

Who this might be right for
Acute Myeloid Leukaemia (AML)Myelodysplastic Syndromes (MDS)
Goethe University 52
Testing effectiveness (Phase 2)Ended earlyNCT03404193
What this trial is testing

Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlastic Plasmacytoid Dendritic Cell Neoplasm+12 more
M.D. Anderson Cancer Center 235
Large-scale testing (Phase 3)Looking for participantsNCT06641414
What this trial is testing

Lisaftoclax (APG-2575) Combined With Azacytidine (AZA) in the Treatment of Patients With Higher-risk Myelodysplastic Syndrome (GLORA-4).

Who this might be right for
Higher-risk Myelodysplastic Syndrome
Ascentage Pharma Group Inc. 490
Testing effectiveness (Phase 2)Study completedNCT01980056
What this trial is testing

Vosaroxin for Intermediate 2 or High-risk MDS After Failure With Hypomethylating Agent-based Therapy

Who this might be right for
Myelodysplastic Syndrome
Weill Medical College of Cornell University 10
Early research (Phase 1)Ended earlyNCT00963495
What this trial is testing

Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphocytic LeukemiaChronic Lymphocytic Leukemia+4 more
University Health Network, Toronto 11
Early research (Phase 1)Study completedNCT02038777
What this trial is testing

PF-04449913 In Japanese Patients With Select Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia
Pfizer 48
Testing effectiveness (Phase 2)Study completedNCT00744536
What this trial is testing

Efficacy Study of Revlimid® and Low Dose Continuously Administered Melphalan to Treat High Risk MDS

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicAngiogenesis
Sunnybrook Health Sciences Centre 20
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