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Results for “High Risk Myelodysplastic Syndrome”

566 trials

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Showing 20 of 566 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07283900
What this trial is testing

Ascorbate in Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndromes
Prajwal Dhakal 38
Early research (Phase 1)Study completedNCT01757639
What this trial is testing

Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaMyelodysplastic Syndrome+3 more
National Cancer Institute (NCI) 42
Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Testing effectiveness (Phase 2)UnknownNCT00242515
What this trial is testing

T-cell Depleted Donor Lymphocyte Infusion (DLI)for Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
National University Hospital, Singapore 16
Large-scale testing (Phase 3)Study completedNCT00412360
What this trial is testing

Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphocytic LeukemiaChronic Myelogenous Leukemia+2 more
Medical College of Wisconsin 224
Early research (Phase 1)Ended earlyNCT02641002
What this trial is testing

CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Celgene 28
Testing effectiveness (Phase 2)UnknownNCT00885508
What this trial is testing

The Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q

Who this might be right for
Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaAcute Myeloid Leukemia
Groupe Francophone des Myelodysplasies 85
Testing effectiveness (Phase 2)Study completedNCT01995578
What this trial is testing

Maintenance Low Dose 5'-Azacitidine Post T Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Myelodysplastic Syndrome and Acute Myelogenous Leukemia With High Risk for Post-Transplant Relapse

Who this might be right for
Myelodysplastic Syndromes (MDS)Acute Myelogenous Leukemia (AML)
Memorial Sloan Kettering Cancer Center 32
Testing effectiveness (Phase 2)Looking for participantsNCT06802315
What this trial is testing

Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myeloid Leukemia, Relapsed, AdultAcute Myeloid Leukemia RefractoryChronic Myeloid Leukemia - Accelerated Phase+1 more
University of Illinois at Chicago
Testing effectiveness (Phase 2)Study completedNCT02169791
What this trial is testing

Nonmyeloablative Haploidentical Transplant Followed by MLN9708

Who this might be right for
Acute LeukemiaChronic LeukemiaMyelodysplastic Syndrome+2 more
Northside Hospital, Inc. 29
Testing effectiveness (Phase 2)Study completedNCT00394381
What this trial is testing

Autologous Cytokine-induced Killer Cell Adoptive Immunotherapy for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome, High Grade
Singapore General Hospital 17
Not applicableLooking for participantsNCT05326919
What this trial is testing

The Patient Cohort of the National Center for Precision Medicine in Leukemia

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaHigh-risk Myelodysplastic Syndrome+2 more
Assistance Publique - Hôpitaux de Paris 3,000
Early research (Phase 1)Temporarily pausedNCT04511975
What this trial is testing

A Study Evaluating the Safety and Efficacy of IBI188 in Combination With AZA in Subjects With Newly Diagnosed MDS

Who this might be right for
MDS
Innovent Biologics (Suzhou) Co. Ltd. 32
Early research (Phase 1)Study completedNCT01471067
What this trial is testing

Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies

Who this might be right for
Blood And Marrow TransplantationLeukemiaLymphoma+2 more
M.D. Anderson Cancer Center 33
Large-scale testing (Phase 3)Ended earlyNCT04266301
What this trial is testing

Study of Efficacy and Safety of MBG453 in Combination With Azacitidine in Subjects With Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS) as Per IPSS-R, or Chronic Myelomonocytic Leukemia-2 (CMML-2)

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, Chronic
Novartis Pharmaceuticals 530
Early research (Phase 1)Study completedNCT00840931
What this trial is testing

Immunotherapy Using Lenalidomide + Bystander Vaccine in High Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia
H. Lee Moffitt Cancer Center and Research Institute 22
Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Early research (Phase 1)Looking for participantsNCT06594445
What this trial is testing

HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML

Who this might be right for
Myeloid MalignancyAcute Myeloid LeukemiaMyelodysplastic Syndromes
Masonic Cancer Center, University of Minnesota 45
Testing effectiveness (Phase 2)Study completedNCT00673114
What this trial is testing

Unrelated Cord Blood Transplant Plus a Haplo-Identical (Half-Matched), T-Cell Depleted Stem Transplant From a Related Donor for Subjects With High Risk Malignancies

Who this might be right for
Hematologic MalignancyMyelodysplastic Syndrome (MDS)Aplastic Anemia
Joanne Kurtzberg, MD 3
Early research (Phase 1)Study completedNCT00077558
What this trial is testing

3-AP Followed By Fludarabine In Treating Patients With Relapsed or Refractory Acute or Chronic Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Diseases
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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