Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “High-Grade Glioma (WHO III-IV)”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 14 of 0 results

Early research (Phase 1)Looking for participantsNCT06964737
What this trial is testing

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

Who this might be right for
Recurrent Malignant GliomaRecurrent WHO Grade 3 GliomaRecurrent WHO Grade 4 Glioma+3 more
Ohio State University Comprehensive Cancer Center 30
Early research (Phase 1)Looking for participantsNCT06253234
What this trial is testing

Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas

Who this might be right for
WHO Grade III GliomasWHO Grade IV Gliomas
Beijing Tiantan Hospital 12
Testing effectiveness (Phase 2)Study completedNCT02590263
What this trial is testing

Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma

Who this might be right for
Malignant GliomaGlioblastoma Multiforme
AbbVie 53
Large-scale testing (Phase 3)Study completedNCT01167322
What this trial is testing

Study of NPC-07 for Fluorescence-guided Resection of Malignant Gliomas

Who this might be right for
Malignant Glioma
Nobelpharma 45
Not applicableLooking for participantsNCT05839379
What this trial is testing

Targeted Pediatric High-Grade Glioma Therapy

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 350
Testing effectiveness (Phase 2)Study completedNCT02343406
What this trial is testing

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas

Who this might be right for
Glioblastoma
AbbVie 266
Not applicableStudy completedNCT02041611
What this trial is testing

Prospective Evaluation of T-cell Immune Status in Patients With Newly Diagnosed High Grade Gliomas

Who this might be right for
High Grade Glioma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 20
Not applicableLooking for participantsNCT07488754
What this trial is testing

Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) In Newly Diagnosed Glioma (WHO G3-G4)

Who this might be right for
GlioblastomaHigh-Grade Glioma (WHO III-IV)Glioblastoma (GBM)
Medical University of Warsaw 35
Testing effectiveness (Phase 2)Study completedNCT01204684
What this trial is testing

Dendritic Cell Vaccine for Patients With Brain Tumors

Who this might be right for
GliomaAnaplastic AstrocytomaAnaplastic Astro-oligodendroglioma+1 more
Jonsson Comprehensive Cancer Center 24
Early research (Phase 1)Active Not RecruitingNCT03749187
What this trial is testing

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

Who this might be right for
GlioblastomaIDH1 Gene MutationIDH2 Gene Mutation+7 more
University of California, San Francisco 78
Very early researchWithdrawnNCT03193463
What this trial is testing

Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy

Who this might be right for
Glioma
Michael Vogelbaum, MD, PhD
Very early researchEnded earlyNCT03927274
What this trial is testing

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

Who this might be right for
Glioma of Brain
H. Lee Moffitt Cancer Center and Research Institute 3
Early research (Phase 1)Looking for participantsNCT06666712
What this trial is testing

Chronic CED of TPT for Recurrent Malignant Glioma

Who this might be right for
Brain Tumor, RecurrentMalignant Glioma (WHO Grade III or IV)IDH1/IDH2 Mutation
Jeffrey N. Bruce 6
Not applicableStudy completedNCT03323450
What this trial is testing

Cognitive Remediation Therapy for Brain Tumor Patients: Improving Working Memory

Who this might be right for
GliomaBrain Tumor, Primary
Virginia Commonwealth University 20