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Results for “High-Risk Acute Myeloid Leukemia”

626 trials

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Showing 20 of 626 results

Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Testing effectiveness (Phase 2)Looking for participantsNCT03661307
What this trial is testing

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+2 more
M.D. Anderson Cancer Center 73
Early research (Phase 1)Looking for participantsNCT04375631
What this trial is testing

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+6 more
Fred Hutchinson Cancer Center 120
Testing effectiveness (Phase 2)Ended earlyNCT01135329
What this trial is testing

Reduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hematologic Cancers

Who this might be right for
LymphomaLeukemiaMyelodysplastic Syndrome
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 15
Testing effectiveness (Phase 2)WithdrawnNCT01652014
What this trial is testing

Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in Remission+51 more
University of Medicine and Dentistry of New Jersey
Early research (Phase 1)UnknownNCT01716364
What this trial is testing

Safety Study of Anti LewisY Chimeric Antigen Receptor in Myeloma, Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Multiple MyelomaAcute Myeloid LeukaemiaMyelodysplastic Syndrome
Peter MacCallum Cancer Centre, Australia 6
Testing effectiveness (Phase 2)Ended earlyNCT05918055
What this trial is testing

Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
National Cancer Institute (NCI) 3
Early research (Phase 1)Study completedNCT00093483
What this trial is testing

Arsenic Trioxide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Roswell Park Cancer Institute 61
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06598969
What this trial is testing

TMLI Plus Chemotherapy in High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Myelodysplastic SyndromesMyeloid Leukemia, Acute
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 58
Testing effectiveness (Phase 2)WithdrawnNCT05367401
What this trial is testing

Sabatolimab and Magrolimab-based Treatment in AML or Higher Risk MDS Participants

Who this might be right for
Myelodysplastic SyndromesAcute Myeloid Leukemia
Novartis Pharmaceuticals
Early research (Phase 1)Ended earlyNCT05155709
What this trial is testing

Siremadlin in Combination With Venetoclax Plus Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Chemotherapy.

Who this might be right for
Acute Myeloid Leukemia
Novartis Pharmaceuticals 14
Early research (Phase 1)Ended earlyNCT01636609
What this trial is testing

Tosedostat and Cytarabine or Azacitidine in Treating Older Participants With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaHigh Risk Myelodysplastic Syndrome
M.D. Anderson Cancer Center 18
Large-scale testing (Phase 3)Study completedNCT00495287
What this trial is testing

A Remission Induction Therapy and Risk-oriented Postremission Strategy for Adult Acute Myelogenous Leukemia (AML)

Who this might be right for
Acute Myelogenous Leukemia
Northern Italy Leukemia Group 573
Testing effectiveness (Phase 2)Looking for participantsNCT06262438
What this trial is testing

CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients

Who this might be right for
Acute Myeloid Leukemia in Children
Princess Maxima Center for Pediatric Oncology 60
Large-scale testing (Phase 3)UnknownNCT04175587
What this trial is testing

Randomized,International Multi-center Clinical Trial of RIF Plus RA for Non-high-risk APL

Who this might be right for
Acute Promyelocytic Leukaemia
Peking University People's Hospital 109
Testing effectiveness (Phase 2)Ended earlyNCT01532635
What this trial is testing

A Two-Step Approach to Bone Marrow Transplant Using Cells From Two Partially-Matched Relatives

Who this might be right for
Hematologic MalignancyLeukemiaAcute Lymphoblastic Leukemia+9 more
Sidney Kimmel Cancer Center at Thomas Jefferson University 4
Testing effectiveness (Phase 2)Looking for participantsNCT07304232
What this trial is testing

Post-transplantation Maintenance Therapy With Cidabenamide in Patients With Intermediate/High-risk AML

Who this might be right for
Allogeneic Hematopoietic Cell Transplantation (HCT)AML (Acute Myeloid Leukemia)
Institute of Hematology & Blood Diseases Hospital, China 134
Early research (Phase 1)Study completedNCT00374933
What this trial is testing

Enhancing Graft vs Leukemia Via Delayed Ex-Vivo Co-Stimulated DLI After Non-Myeloablative Stem Cell Transplantation

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome
Abramson Cancer Center at Penn Medicine 18
Large-scale testing (Phase 3)Study completedNCT00880243
What this trial is testing

Effect of Priming During Induction and Consolidations in Younger Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Acute Leukemia French Association 473
Not applicableEnded earlyNCT04185428
What this trial is testing

Investigating Integrative Therapies for Symptom Management in Adults With Acute Leukemia

Who this might be right for
Acute Myeloid Leukemia
University of Florida 9
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