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Results for “High-Risk Non-Muscle Invasive Bladder Cancer”

148 trials

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Showing 20 of 148 results

Testing effectiveness (Phase 2)Study completedNCT02625961
What this trial is testing

Study of Pembrolizumab (MK-3475) and Pembrolizumab With Other Investigational Agents in Participants With High Risk Non-muscle Invasive Bladder Cancer (MK-3475-057/KEYNOTE-057)

Who this might be right for
Bladder Cancer
Merck Sharp & Dohme LLC 296
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07322263
What this trial is testing

Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

Who this might be right for
Bladder CancerNon-Muscle Invasive Bladder Cancer (NMIBC)Urothelial Carcinoma+8 more
Michael A. O'Donnell 174
Testing effectiveness (Phase 2)WithdrawnNCT02143804
What this trial is testing

Safety and Efficacy of CG0070 Oncolytic Virus Regimen in Patients With High Grade Non-Muscle Invasive Bladder Cancer

Who this might be right for
Bladder CancerHigh GradeNon Muscle Invasive
CG Oncology, Inc.
Testing effectiveness (Phase 2)Active Not RecruitingNCT04640623
What this trial is testing

TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

Who this might be right for
Urinary Bladder Neoplasms
Janssen Research & Development, LLC 220
Testing effectiveness (Phase 2)Study completedNCT04387461
What this trial is testing

Study of CG0070 Given in Combination With Pembrolizumab, in Non-Muscle Invasive Bladder Cancer, Unresponsive to Bacillus Calmette-Guerin

Who this might be right for
Non Muscle Invasive Bladder Cancer
CG Oncology, Inc. 35
Early research (Phase 1)Study completedNCT03191578
What this trial is testing

Immunological Response to Intravesical BCG Therapy of Superficial Bladder Cancer by Prior Administration of RUTI®

Who this might be right for
High-Risk Non-Muscle-Invasive Bladder Cancer
Archivel Farma S.L. 44
Large-scale testing (Phase 3)Looking for participantsNCT06441110
What this trial is testing

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Who this might be right for
Urinary Bladder NeoplasmsBCG VaccineImmunotherapy, Active+3 more
Fujian Medical University Union Hospital 76
Not applicableEnded earlyNCT04412070
What this trial is testing

Assessement of the Concordance of Genomic Alterations Between Urine and Tissue in High-Risk NMIBC Patients

Who this might be right for
Bladder Cancer
Hopital Foch 20
Testing effectiveness (Phase 2)Ended earlyNCT03519256
What this trial is testing

Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 With or Without Bacillus Calumette-Guerin (BCG) in BCG Unresponsive Bladder Cancer That Has Not Invaded Into the Muscle Wall of the Bladder

Who this might be right for
Urinary Bladder Neoplasms
Bristol-Myers Squibb 142
Not applicableUnknownNCT05332353
What this trial is testing

Machine Learning-Based Prediction of BCG Response in High-Risk Non-Muscle Invasive Bladder Cancer Patients

Who this might be right for
Non-Muscle Invasive Bladder Cancer
Mansoura University 100
Testing effectiveness (Phase 2)Looking for participantsNCT06378242
What this trial is testing

To Evaluate the Safety, Efficacy, and Pharmacokinetics of Intravesical Instiliations of Disitamab Vedotin in Patients With High-risk Non-muscular Invasive Bladder Cancer (NMIBC) That Express HER2

Who this might be right for
High-risk Non-muscle Invasive Bladder Cancer
RemeGen Co., Ltd. 24
Large-scale testing (Phase 3)UnknownNCT03664869
What this trial is testing

Electromotive Mitomycin-C (EMDA-MMC) in Preventing Recurrences in High-risk Non-muscle-invasive Bladder Cancer

Who this might be right for
Bladder Cancer
Turku University Hospital 300
Large-scale testing (Phase 3)Active Not RecruitingNCT03528694
What this trial is testing

Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer

Who this might be right for
Non-muscle-invasive Bladder Cancer
AstraZeneca 1,018
Not applicableEnded earlyNCT04142359
What this trial is testing

PK Sub-Study of QUILT-3.032 (CA ALT-803-01-16) and of QUILT-2.005 (CA ALT-803-01-14)

Who this might be right for
Pharmacokinetics
Altor BioScience 1
Large-scale testing (Phase 3)Active Not RecruitingNCT05704244
What this trial is testing

Safety and Efficacy of FE 999326 Administered Intravesically to Japanese Subjects With High-grade, BCG Unresponsive, Non-muscle Invasive Bladder Cancer (NMIBC)

Who this might be right for
Bladder Cancer
Ferring Pharmaceuticals 25
Early research (Phase 1)Active Not RecruitingNCT04134000
What this trial is testing

Atezolizumab and BCG in High Risk BCG naïve Non-muscle Invasive Bladder Cancer (NMIBC) Patients (BladderGATE)

Who this might be right for
Invasive Bladder Cancer
Fundacion Oncosur 40
Large-scale testing (Phase 3)Active Not RecruitingNCT05943106
What this trial is testing

BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants

Who this might be right for
Non-Muscle- Invasive Bladder Cancer
AstraZeneca 100
Not applicableNot Yet RecruitingNCT07053748
What this trial is testing

Observational Clinical Study on High - Risk NMIBC Patients Choosing Trimodality Bladder - Sparing Therapy

Who this might be right for
High - Risk NMIBC
Peking University First Hospital 30
Not applicableUnknownNCT05547516
What this trial is testing

Blue Laser -5ala Photodynamic Therapy (PDT) in High-Risk Non-muscle Invasive Bladder Cancer (NMIBC) Patients

Who this might be right for
Non-muscle-invasive Bladder Cancer
First Affiliated Hospital Xi'an Jiaotong University 140
Large-scale testing (Phase 3)Not Yet RecruitingNCT07268339
What this trial is testing

A Phase III Randomised Control Clinical Trial of Radiotherapy With Radiosensitisation Versus Intravesical Bacillus Calmette-Guerin Therapy for High-risk Non-muscle Invasive Bladder Cancer.

Who this might be right for
High-Risk Non-Muscle Invasive Bladder Cancer
The Christie NHS Foundation Trust 328
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