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Results for “High-grade Osteosarcoma”

54 trials

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Showing 20 of 54 results

Early research (Phase 1)Active Not RecruitingNCT04616248
What this trial is testing

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaPrognostic Stage IV Breast Cancer AJCC v8+10 more
University of Southern California 14
Large-scale testing (Phase 3)Active Not RecruitingNCT06820957
What this trial is testing

Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body

Who this might be right for
CIC-Rearranged SarcomaMetastatic Ewing SarcomaMetastatic High Grade Sarcoma+4 more
Children's Oncology Group 437
Testing effectiveness (Phase 2)Looking for participantsNCT06650514
What this trial is testing

Pilot Study to Evaluate the Safety and the Anti-Tumour Activity of the Myc Inhibitor OMO-103 Administered Intravenously in Patients With Advanced High-Grade Osteosarcoma

Who this might be right for
OsteosarcomaOsteosarcoma in Children
Vall d'Hebron Institute of Oncology 10
Testing effectiveness (Phase 2)Study completedNCT01459484
What this trial is testing

ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma

Who this might be right for
Osteosarcoma
Italian Sarcoma Group 225
Testing effectiveness (Phase 2)UnknownNCT03063983
What this trial is testing

Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic Osteosarcoma

Who this might be right for
Osteosarcoma
Grupo de Apoio ao Adolescente e a Crianca com Cancer 158
Testing effectiveness (Phase 2)Looking for participantsNCT04698785
What this trial is testing

Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients

Who this might be right for
Bone SarcomaOsteosarcoma
Centre Leon Berard 36
Testing effectiveness (Phase 2)Study completedNCT00743509
What this trial is testing

A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced Sarcoma

Who this might be right for
Osteosarcoma
University of Michigan Rogel Cancer Center 49
Testing effectiveness (Phase 2)Looking for participantsNCT06607692
What this trial is testing

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

Who this might be right for
Solid Tumor CancerMedulloblastomaHigh Risk Neuroblastoma+17 more
Fundación de investigación HM 25
Testing effectiveness (Phase 2)UnknownNCT04351308
What this trial is testing

Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma

Who this might be right for
OsteosarcomaSurvivalChemotherapy Effect+1 more
Peking University People's Hospital 60
Testing effectiveness (Phase 2)Study completedNCT00889057
What this trial is testing

Sorafenib in Relapsed High Grade Osteosarcoma

Who this might be right for
Osteosarcoma
Italian Sarcoma Group 35
Not applicableLooking for participantsNCT06017518
What this trial is testing

An Observational Study of Local Relapse After High Grade Osteosarcoma

Who this might be right for
Osteosarcoma
Istituto Ortopedico Rizzoli 150
Large-scale testing (Phase 3)UnknownNCT04359550
What this trial is testing

Study of ZKAB001 for Maintenance Therapy in Patients With High-grade Osteosarcoma After Adjuvant Chemotherapy

Who this might be right for
High-grade Osteosarcoma
Lee's Pharmaceutical Limited 362
Testing effectiveness (Phase 2)UnknownNCT02273583
What this trial is testing

Prospective Clinical Trial Evaluating Metronomic Chemotherapy in Patients With High-grade, Operable, Non-metastatic Osteosarcoma of the Extremity

Who this might be right for
High Grade Osteosarcoma
Grupo de Apoio ao Adolescente e a Crianca com Cancer 738
Testing effectiveness (Phase 2)Active Not RecruitingNCT05660408
What this trial is testing

RNA Lipid Particles Targeting Pediatric Recurrent Intracranial Malignancies and Other systEmic Solid Tumors

Who this might be right for
Recurrent Pulmonary OsteosarcomaRecurrent High-grade Glioma
University of Florida 36
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Large-scale testing (Phase 3)UnknownNCT00691236
What this trial is testing

Evaluation of Zoledronic Acid as a Single Agent or as an Adjuvant to Chemotherapy in High Grade Osteosarcoma

Who this might be right for
Osteosarcoma
Tata Memorial Hospital 60
Testing effectiveness (Phase 2)WithdrawnNCT05116800
What this trial is testing

Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcoma

Who this might be right for
Soft Tissue SarcomaUndifferentiated Pleomorphic SarcomaMyxofibrosarcoma+10 more
Brown University
Early research (Phase 1)Study completedNCT00303940
What this trial is testing

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorKidney Cancer+5 more
National Institutes of Health Clinical Center (CC) 26
Testing effectiveness (Phase 2)Ended earlyNCT00880542
What this trial is testing

Sorafenib and Ifosfamide in Treating Patients With High-Grade Soft Tissue Sarcoma or Bone Sarcoma That Can Be Removed by Surgery

Who this might be right for
Sarcoma
Jonsson Comprehensive Cancer Center 7
Testing effectiveness (Phase 2)Study completedNCT00091182
What this trial is testing

Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Extragonadal Germ Cell TumorChildhood Hepatoblastoma+23 more
National Cancer Institute (NCI) 180
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