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Results for “High-risk Locally Advanced”

253 trials

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Showing 20 of 253 results

Large-scale testing (Phase 3)Looking for participantsNCT06229041
What this trial is testing

Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi)

Who this might be right for
Rectal Cancer
Peking University Cancer Hospital & Institute 472
Early research (Phase 1)Study completedNCT03801902
What this trial is testing

Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial

Who this might be right for
Locally Advanced Lung Non-Small Cell CarcinomaLocally Recurrent Lung Non-Small Cell CarcinomaStage II Lung Cancer AJCC v8+2 more
National Cancer Institute (NCI) 26
Not applicableLooking for participantsNCT06771193
What this trial is testing

Study on Disease Characteristics and Treatment in Locally Advanced or Recurrent / Metastatic Cervical Cancer in Italy

Who this might be right for
Cervical CancerLocally Advanced Cervical CancerRecurrent Cervical Cancer+1 more
MSD Italia S.r.l. 200
Testing effectiveness (Phase 2)Looking for participantsNCT07647289
What this trial is testing

EV + Toripalimab vs GC as Neoadjuvant Therapy in Locally Advanced/High-Risk MIBC

Who this might be right for
Muscle-Invasive Bladder Cancer (MIBC)
Peking University Third Hospital 58
Large-scale testing (Phase 3)Looking for participantsNCT06079671
What this trial is testing

Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)

Who this might be right for
Locally Advanced Cervical Cancer
AstraZeneca 800
Not applicableEnded earlyNCT02388932
What this trial is testing

Stereotactic Body Radiation Therapy in Treating Patients With High Risk Locally Advanced Head and Neck Cancer

Who this might be right for
Recurrent Hypopharyngeal Squamous Cell CarcinomaRecurrent Laryngeal Squamous Cell CarcinomaRecurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma+25 more
Case Comprehensive Cancer Center 3
Early research (Phase 1)Looking for participantsNCT07503808
What this trial is testing

IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

Who this might be right for
Esophageal Squamous Cell CarcinomaHigh Grade Serous Ovarian CancerHead and Neck Squamous Cell Carcinoma+5 more
IDEAYA Biosciences 150
Testing effectiveness (Phase 2)Ended earlyNCT02956889
What this trial is testing

To Assess The Efficacy And Safety Of Vismodegib And Radiotherapy In Advanced Basal Cell Carcinoma

Who this might be right for
Carcinoma, Basal Cell
Istituto Clinico Humanitas 14
Large-scale testing (Phase 3)Study completedNCT00019682
What this trial is testing

Aldesleukin With or Without Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Melanoma

Who this might be right for
Recurrent MelanomaStage IIIA Skin MelanomaStage IIIB Skin Melanoma+2 more
National Cancer Institute (NCI) 185
Testing effectiveness (Phase 2)Active Not RecruitingNCT06416696
What this trial is testing

Toripalimab for High-risk Locally Advanced Cervical Cancer

Who this might be right for
Cervical Cancers
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 57
Testing effectiveness (Phase 2)Active Not RecruitingNCT04736173
What this trial is testing

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Who this might be right for
Non Small Cell Lung CancerNonsquamous Non Small Cell Lung CancerSquamous Non Small Cell Lung Cancer+1 more
Arcus Biosciences, Inc. 169
Large-scale testing (Phase 3)Looking for participantsNCT06952803
What this trial is testing

Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Who this might be right for
Prostate Cancer
AstraZeneca 700
Large-scale testing (Phase 3)Study completedNCT00024427
What this trial is testing

Triacetyluridine and Fluorouracil Compared With Gemcitabine in Treating Patients With Unresectable Locally Advanced, or Metastatic Pancreatic Cancer

Who this might be right for
Drug/Agent Toxicity by Tissue/OrganPancreatic Cancer
Wellstat Therapeutics 250
Not applicableLooking for participantsNCT04894188
What this trial is testing

Neoadjuvant Hormone and Radiation Therapy Followed by Radical Prostatectomy in Patients With High-Risk Prostate Cancer

Who this might be right for
Prostate Cancer
National Taiwan University Hospital 38
Large-scale testing (Phase 3)Active Not RecruitingNCT03767244
What this trial is testing

Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

Who this might be right for
Prostatic Neoplasms
Janssen Research & Development, LLC 2,517
Not applicableActive Not RecruitingNCT04599309
What this trial is testing

Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
CancerHead and Neck Squamous Cell CarcinomaHead and Neck Cancer
University Health Network, Toronto 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07248020
What this trial is testing

A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor Tissue

Who this might be right for
Rectal CancerLocally Advanced Rectal CancerRadiation-Induced Enteritis+2 more
Chang Gung Memorial Hospital 72
Not applicableUnknownNCT03110497
What this trial is testing

Single Application Brachytherapy in Cervical Cancer

Who this might be right for
Cervical Cancer
Tata Memorial Hospital 40
Testing effectiveness (Phase 2)UnknownNCT05113459
What this trial is testing

Disitamab Vedotin Combined With PD-1 and Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer（RC48-C018）

Who this might be right for
Gastric Cancer
Guoxin Li 40
Testing effectiveness (Phase 2)Looking for participantsNCT06170710
What this trial is testing

Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 173
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