Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “High-risk MDS”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)UnknownNCT03083054
What this trial is testing

Cellular Immunotherapy for Patients With High Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia

Who this might be right for
Myelodysplastic SyndromesAcute Myeloid Leukemia
University of Campinas, Brazil 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT07779031
What this trial is testing

A Single-Arm, Open Phase I Clinical Study of Selinexor in Combination With Azacitidine for the Treatment of High-Risk AML/MDS Patients After Allo-HSCT

Who this might be right for
Acute Myeloid Leukaemia (AML)MDS (Myelodysplastic Syndrome)
Liping Dou 58
Early research (Phase 1)Study completedNCT00004904
What this trial is testing

Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersGraft Versus Host DiseaseLeukemia+5 more
Northwestern University
Testing effectiveness (Phase 2)Active Not RecruitingNCT03330821
What this trial is testing

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia With Myelodysplasia-Related ChangesTherapy-Related Acute Myeloid Leukemia
University of Southern California 53
Testing effectiveness (Phase 2)Study completedNCT01682226
What this trial is testing

Cord Blood With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cell Transplantation for Hematological Malignancies

Who this might be right for
LeukemiaMyelodysplastic SyndromeLymphoma
Memorial Sloan Kettering Cancer Center 84
Early research (Phase 1)Ended earlyNCT00852709
What this trial is testing

Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemias

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid LeukemiaMyeloproliferative Disorders+7 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT05583552
What this trial is testing

Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy

Who this might be right for
Myelodysplastic SyndromesAcute Myeloid Leukemia
GCP-Service International West GmbH 46
Testing effectiveness (Phase 2)Looking for participantsNCT04644016
What this trial is testing

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

Who this might be right for
AMLALLMDS+6 more
Memorial Sloan Kettering Cancer Center 31
Testing effectiveness (Phase 2)Study completedNCT00656617
What this trial is testing

Phase II Study of Idarubicin, Cytarabine, and Vorinostat With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)
M.D. Anderson Cancer Center 106
Early research (Phase 1)Study completedNCT03600155
What this trial is testing

Nivolumab and Ipilimumab After Donor Stem Cell Transplant in Treating Patients With High Risk Refractory or Relapsed Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Allogeneic Hematopoietic Stem Cell Transplantation RecipientMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+1 more
M.D. Anderson Cancer Center 29
Not applicableUnknownNCT03903055
What this trial is testing

Study on High-risk MDS Patients Based on RNA-seq Technology

Who this might be right for
MDS
Zhejiang Provincial Hospital of TCM 120
Large-scale testing (Phase 3)Active Not RecruitingNCT04401748
What this trial is testing

Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndrome (MDS)
AbbVie 531
Testing effectiveness (Phase 2)Study completedNCT02294552
What this trial is testing

Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoid LeukemiaLymphoma+3 more
Ivan S Moiseev 200
Testing effectiveness (Phase 2)Temporarily pausedNCT04278768
What this trial is testing

Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
Curis, Inc. 366
Testing effectiveness (Phase 2)Study completedNCT01236144
What this trial is testing

A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome.

Who this might be right for
Acute Myeloid LeukaemiaHigh Risk Myelodysplastic Syndrome
Cardiff University 113
Testing effectiveness (Phase 2)Ended earlyNCT00374296
What this trial is testing

MGCD0103 in Elderly Patients With Previously Untreated AML/High Risk MDS or Adults With Relapsed/Refractory Disease

Who this might be right for
Myelogenous Leukemia, AcuteMyelodysplastic Syndromes
Mirati Therapeutics Inc. 35
Testing effectiveness (Phase 2)Study completedNCT00339196
What this trial is testing

5-azacytidine Valproic Acid and ATRA in AML and High Risk MDS

Who this might be right for
Acute Myelogenous Leukaemia (AML)Myelodysplastic Syndrome (MDS)
Assistance Publique - Hôpitaux de Paris 25
Early research (Phase 1)WithdrawnNCT04361058
What this trial is testing

Nivolumab for High-Risk MDS/AML Patients After Allogeneic Stem Cell Transplant With Post-Transplant Cyclophosphamide

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic SyndromesMyelodysplastic Syndrome Acute Myeloid Leukemia
SCRI Development Innovations, LLC
Testing effectiveness (Phase 2)Looking for participantsNCT06471946
What this trial is testing

VA Conditioning Regimen Allo-HSCT for Elderly Higher-risk MDS

Who this might be right for
Higher-risk Myelodysplastic Syndromes
Navy General Hospital, Beijing 54
Early research (Phase 1)Looking for participantsNCT03113643
What this trial is testing

SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeBlastic Plasmacytoid Dendritic Cell Neoplasm
Dana-Farber Cancer Institute 72
Next Page