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Results for “High-risk Myelodysplastic Syndrome (MDS)”

570 trials

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Showing 20 of 570 results

Testing effectiveness (Phase 2)Study completedNCT00339196
What this trial is testing

5-azacytidine Valproic Acid and ATRA in AML and High Risk MDS

Who this might be right for
Acute Myelogenous Leukaemia (AML)Myelodysplastic Syndrome (MDS)
Assistance Publique - Hôpitaux de Paris 25
Testing effectiveness (Phase 2)Looking for participantsNCT06046313
What this trial is testing

Prolonged Ultra Low-dose Decitabine Plus Venetoclax for Primary Diagnosed Elderly AMLK/MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
First Affiliated Hospital of Zhejiang University 120
Large-scale testing (Phase 3)Looking for participantsNCT04184505
What this trial is testing

Feasibility of Allogeneic Stem Cell Transplantation in Higher-risk-MDS (ACROBAT)

Who this might be right for
High-risk MDS
Gruppo Italiano Malattie EMatologiche dell'Adulto 274
Testing effectiveness (Phase 2)Study completedNCT00003116
What this trial is testing

High-Dose Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+2 more
Case Comprehensive Cancer Center 66
Testing effectiveness (Phase 2)UnknownNCT05066958
What this trial is testing

Ex-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCT

Who this might be right for
Acute Myeloid LeukemiaHigh Risk Acute Myeloid LeukemiaAcute Lymphoblastic Leukemia, in Relapse+4 more
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 20
Early research (Phase 1)Looking for participantsNCT04243785
What this trial is testing

BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
Edgewood Oncology Inc. 80
Early research (Phase 1)Looking for participantsNCT07107126
What this trial is testing

Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
Remedy Plan, Inc. 24
Testing effectiveness (Phase 2)Looking for participantsNCT05601726
What this trial is testing

First-in-human Study Aiming to Characterize the Safety, Tolerability, Pharmacokinetic and Preliminary Signs of Activity of ABD-3001 in Refractory or Relapsed AML and High Risk MDS Adult Patients

Who this might be right for
Acute Myeloid Leukemia, AdultMyelodysplastic Syndromes
Advanced BioDesign 36
Testing effectiveness (Phase 2)Looking for participantsNCT07046078
What this trial is testing

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Myeloid LeukemiaChronic Myelomonocytic Leukemia+1 more
Fred Hutchinson Cancer Center
Early research (Phase 1)UnknownNCT01277484
What this trial is testing

Dose Finding Study of Post-BMT Decitabine Maintenance Treatment in Higher-risk MDS and MDS/AML

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid Leukemia
Seoul St. Mary's Hospital 19
Testing effectiveness (Phase 2)Ended earlyNCT03214666
What this trial is testing

GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies

Who this might be right for
High-risk Myelodysplastic SyndromesAcute Myelogenous LeukemiaSystemic Mastocytosis+1 more
GT Biopharma, Inc. 12
Early research (Phase 1)Study completedNCT00588991
What this trial is testing

Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders

Who this might be right for
Adult Acute Megakaryoblastic LeukemiaAdult Acute Monoblastic LeukemiaAdult Acute Monocytic Leukemia+20 more
National Cancer Institute (NCI) 12
Testing effectiveness (Phase 2)Study completedNCT00050154
What this trial is testing

Study of Tipifarnib in Patients With High-Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Myelodysplastic Syndrome
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 82
Not applicableActive Not RecruitingNCT02670525
What this trial is testing

Matched Targeted Therapy For High-Risk Leukemias and Myelodysplastic Syndrome

Who this might be right for
Recurrent, Refractory, or High Risk LeukemiasMatched Targeted Therapy
Dana-Farber Cancer Institute 338
Testing effectiveness (Phase 2)Study completedNCT01839916
What this trial is testing

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)+61 more
University of Chicago 77
Early research (Phase 1)Ended earlyNCT02846376
What this trial is testing

Single Agent and Combined Inhibition After Allogeneic Stem Cell Transplant

Who this might be right for
Acute Myeloid Leukemia and Myelodysplastic Syndrome
Hackensack Meridian Health 8
Not applicableEnded earlyNCT00967525
What this trial is testing

Intraosseous Infusion of Unrelated Cord Blood Grafts

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+1 more
Emory University 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT01885689
What this trial is testing

Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia

Who this might be right for
Adult Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Myeloid Leukemia in Remission+4 more
City of Hope Medical Center
Not applicableStudy completedNCT00293384
What this trial is testing

Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell Transplant

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+9 more
Barbara Ann Karmanos Cancer Institute 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07214064
What this trial is testing

Venetoclax- Augmented Treosulfan-Based Reduced Intensity Conditioning Before Allogeneic Stem Cell Transplantation

Who this might be right for
AML (Acute Myeloid Leukemia)MDS/AMLMDS (Myelodysplastic Syndrome)
University Hospital Tuebingen 27
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