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Results for “High-risk Myelodysplastic Syndrome (MDS)”

566 trials

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Showing 20 of 566 results

Testing effectiveness (Phase 2)Study completedNCT00533923
What this trial is testing

Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders

Who this might be right for
AMLALLCLL+6 more
Beth Israel Deaconess Medical Center 25
Testing effectiveness (Phase 2)Study completedNCT00050154
What this trial is testing

Study of Tipifarnib in Patients With High-Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Myelodysplastic Syndrome
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 82
Testing effectiveness (Phase 2)Looking for participantsNCT03661307
What this trial is testing

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+2 more
M.D. Anderson Cancer Center 73
Early research (Phase 1)Looking for participantsNCT04375631
What this trial is testing

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+6 more
Fred Hutchinson Cancer Center 120
Testing effectiveness (Phase 2)Study completedNCT02159872
What this trial is testing

Omacetaxine in Patients With Intermediate-1 and Higher Risk Myelodysplastic Syndrome (MDS) Post Hypomethylating Agent (HMA) Failure

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 48
Testing effectiveness (Phase 2)Ended earlyNCT01135329
What this trial is testing

Reduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hematologic Cancers

Who this might be right for
LymphomaLeukemiaMyelodysplastic Syndrome
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 15
Testing effectiveness (Phase 2)WithdrawnNCT01652014
What this trial is testing

Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in Remission+51 more
University of Medicine and Dentistry of New Jersey
Early research (Phase 1)UnknownNCT01716364
What this trial is testing

Safety Study of Anti LewisY Chimeric Antigen Receptor in Myeloma, Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Multiple MyelomaAcute Myeloid LeukaemiaMyelodysplastic Syndrome
Peter MacCallum Cancer Centre, Australia 6
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07283900
What this trial is testing

Ascorbate in Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndromes
Prajwal Dhakal 38
Testing effectiveness (Phase 2)Ended earlyNCT05918055
What this trial is testing

Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
National Cancer Institute (NCI) 3
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06598969
What this trial is testing

TMLI Plus Chemotherapy in High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Myelodysplastic SyndromesMyeloid Leukemia, Acute
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 58
Testing effectiveness (Phase 2)WithdrawnNCT05367401
What this trial is testing

Sabatolimab and Magrolimab-based Treatment in AML or Higher Risk MDS Participants

Who this might be right for
Myelodysplastic SyndromesAcute Myeloid Leukemia
Novartis Pharmaceuticals
Early research (Phase 1)Ended earlyNCT01636609
What this trial is testing

Tosedostat and Cytarabine or Azacitidine in Treating Older Participants With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaHigh Risk Myelodysplastic Syndrome
M.D. Anderson Cancer Center 18
Early research (Phase 1)Study completedNCT00374933
What this trial is testing

Enhancing Graft vs Leukemia Via Delayed Ex-Vivo Co-Stimulated DLI After Non-Myeloablative Stem Cell Transplantation

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome
Abramson Cancer Center at Penn Medicine 18
Testing effectiveness (Phase 2)Looking for participantsNCT06013423
What this trial is testing

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+7 more
Fred Hutchinson Cancer Center 54
Not applicableUnknownNCT03217903
What this trial is testing

High Risk Myelodysplasia Treated by Azacytidine : Genetic and Epigenetic (MYRAGE)

Who this might be right for
High-risk Myelodysplastic Syndromes With Excess Blasts
Central Hospital, Nancy, France 32
Testing effectiveness (Phase 2)Looking for participantsNCT03999723
What this trial is testing

Combining Active and Passive DNA Hypomethylation

Who this might be right for
Myelodysplastic SyndromesAcute Myeloid LeukemiaChronic Myelomonocytic Leukemia
Kirsten Grønbæk 196
Testing effectiveness (Phase 2)Study completedNCT00255346
What this trial is testing

Dasatinib as Therapy for Myeloproliferative Disorders (MPDs)

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesAgnogenic Myeloid Metaplasia+5 more
M.D. Anderson Cancer Center 68
Testing effectiveness (Phase 2)Looking for participantsNCT02727803
What this trial is testing

Personalized NK Cell Therapy in CBT

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Lymphoblastic Leukemia+23 more
M.D. Anderson Cancer Center 100
Large-scale testing (Phase 3)Study completedNCT00008359
What this trial is testing

Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment

Who this might be right for
Cancer
Memorial Sloan Kettering Cancer Center
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