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Results for “High-risk Myelodysplastic Syndromes With Excess Blasts”

63 trials

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Showing 20 of 63 results

Early research (Phase 1)Study completedNCT01300572
What this trial is testing

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Who this might be right for
Chronic Myelomonocytic LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Lymphoblastic Leukemia+3 more
Fred Hutchinson Cancer Center 16
Testing effectiveness (Phase 2)Study completedNCT00096122
What this trial is testing

Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+20 more
National Cancer Institute (NCI) 95
Testing effectiveness (Phase 2)Study completedNCT01168219
What this trial is testing

Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaAdult Acute Megakaryoblastic LeukemiaAdult Acute Monoblastic Leukemia+17 more
National Cancer Institute (NCI) 68
Testing effectiveness (Phase 2)Looking for participantsNCT05735717
What this trial is testing

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Who this might be right for
Hematologic MalignancyAcute LeukemiaRemission+21 more
Masonic Cancer Center, University of Minnesota 70
Early research (Phase 1)Ended earlyNCT00589316
What this trial is testing

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+7 more
Fred Hutchinson Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT04849910
What this trial is testing

Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDS

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Vor Biopharma 67
Testing effectiveness (Phase 2)WithdrawnNCT02765997
What this trial is testing

StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphocytic LeukemiaChronic Myelogenous Leukemia+1 more
Masonic Cancer Center, University of Minnesota
Testing effectiveness (Phase 2)Study completedNCT00077116
What this trial is testing

Idarubicin, Cytarabine, and Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia Secondary to Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic Syndromes
European Organisation for Research and Treatment of Cancer - EORTC 31
Testing effectiveness (Phase 2)Study completedNCT00002833
What this trial is testing

Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemia

Who this might be right for
Graft Versus Host DiseaseLeukemiaMyelodysplastic Syndromes
M.D. Anderson Cancer Center 53
Testing effectiveness (Phase 2)Looking for participantsNCT06839456
What this trial is testing

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Who this might be right for
LeukemiaHigh Risk Acute Lymphoblastic LeukemiaHigh Risk Acute Myeloid Leukemia+11 more
Children's Hospital of Philadelphia 100
Large-scale testing (Phase 3)Study completedNCT00005823
What this trial is testing

Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Neoplasms
Leukemia Research Fund 2,000
Testing effectiveness (Phase 2)Study completedNCT01101880
What this trial is testing

Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasm

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+8 more
University of Washington 50
Testing effectiveness (Phase 2)WithdrawnNCT01163201
What this trial is testing

T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies

Who this might be right for
Hematologic MalignancyAcute Myeloid LeukemiaAcute Lymphocytic Leukemia+14 more
Masonic Cancer Center, University of Minnesota
Testing effectiveness (Phase 2)Ended earlyNCT00740181
What this trial is testing

Decitabine, Cytarabine, GCSF for Refractory AML/MDS

Who this might be right for
MyelodysplasiaLeukemia
Brown University 9
Early research (Phase 1)Ended earlyNCT00376519
What this trial is testing

Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+3 more
Masonic Cancer Center, University of Minnesota 3
Large-scale testing (Phase 3)Study completedNCT00046930
What this trial is testing

Daunorubicin & Cytarabine +/- Zosuquidar inTreating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or Refractory Anemia

Who this might be right for
LeukemiaMyelodysplastic Syndromes
Eastern Cooperative Oncology Group 449
Testing effectiveness (Phase 2)WithdrawnNCT00003407
What this trial is testing

Amifostine & High-Dose Combination Chemotherapy in Treating Patients With Acute ML or CML

Who this might be right for
Drug/Agent Toxicity by Tissue/OrganLeukemiaMyelodysplastic Syndromes+1 more
Rush University Medical Center
Not applicableUnknownNCT02905552
What this trial is testing

Myelodysplasic Syndromes and Risk Factors for Infection

Who this might be right for
Myelodysplastic Syndrome (MDS)InfectionRisk Factors+1 more
Assistance Publique - Hôpitaux de Paris 320
Testing effectiveness (Phase 2)Study completedNCT01422603
What this trial is testing

Clofarabine Pre-conditioning With Allogeneic Transplant for Acute Myeloid Leukaemia (AML)

Who this might be right for
Acute Myeloid LeukaemiaMyelodysplasia
University Hospital Southampton NHS Foundation Trust 9
Early research (Phase 1)Active Not RecruitingNCT02530034
What this trial is testing

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveHematopoietic and Lymphoid Cell Neoplasm+8 more
M.D. Anderson Cancer Center 72
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