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Results for “High-risk NMIBC”

91 trials

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Showing 20 of 91 results

Large-scale testing (Phase 3)Active Not RecruitingNCT03022825
What this trial is testing

QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer

Who this might be right for
Bladder Cancer
ImmunityBio, Inc. 190
Testing effectiveness (Phase 2)UnknownNCT05957757
What this trial is testing

RC48 Combined With Tislelizumab for Bladder Sparing Treatment in NMIBC With BCG Treatment Failure and HER2 Expression

Who this might be right for
Non-Muscle Invasive Bladder CancerHER2
RenJi Hospital 20
Large-scale testing (Phase 3)WithdrawnNCT07551544
What this trial is testing

ANKTIVA Plus BCG Versus BCG Monotherapy In Participants With BCG-Naïve/BCG-Exposed High-Grade Non-Muscle Invasive Papillary Bladder Cancer

Who this might be right for
NMIBC
ImmunityBio, Inc.
Testing effectiveness (Phase 2)Study completedNCT02365818
What this trial is testing

Safety and Efficacy of CG0070 Oncolytic Virus Regimen for High Grade NMIBC After BCG Failure

Who this might be right for
Bladder Cancer
CG Oncology, Inc. 66
Not applicableLooking for participantsNCT06991868
What this trial is testing

Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD)

Who this might be right for
NMIBCMIBCUTUC
Peking University First Hospital 300
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07189793
What this trial is testing

Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study

Who this might be right for
Urinary Bladder NeoplasmsCarcinoma, Transitional CellCarcinoma in Situ of Bladder+1 more
First Affiliated Hospital of Wenzhou Medical University 106
Large-scale testing (Phase 3)Active Not RecruitingNCT05704244
What this trial is testing

Safety and Efficacy of FE 999326 Administered Intravesically to Japanese Subjects With High-grade, BCG Unresponsive, Non-muscle Invasive Bladder Cancer (NMIBC)

Who this might be right for
Bladder Cancer
Ferring Pharmaceuticals 25
Large-scale testing (Phase 3)Study completedNCT02773849
What this trial is testing

ADSTILADRIN (=INSTILADRIN) in Patients With High-Grade, Bacillus Calmette-Guerin (BCG) Unresponsive Non-Muscle Invasive Bladder Cancer (NMIBC)

Who this might be right for
Superficial Bladder Cancer
Ferring Pharmaceuticals 157
Testing effectiveness (Phase 2)UnknownNCT05975151
What this trial is testing

Efficacy and Safety of Pseudomonas Aeruginosa for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Who this might be right for
Bladder Cancer
Qilu Hospital of Shandong University 63
Testing effectiveness (Phase 2)Study completedNCT02015104
What this trial is testing

Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG

Who this might be right for
Bladder Cancer
National Cancer Institute (NCI) 32
Post-approval studies (Phase 4)Active Not RecruitingNCT04701151
What this trial is testing

NORTH-REG Dwell-Time Study

Who this might be right for
Side Effect of Drug
Jørgen Bjerggaard Jensen 314
Early research (Phase 1)Active Not RecruitingNCT05768347
What this trial is testing

Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC

Who this might be right for
Urothelial CarcinomaNon-Invasive Bladder Urothelial Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 9
Large-scale testing (Phase 3)Looking for participantsNCT05037279
What this trial is testing

Evaluating Safety and Efficacy of Verity-BCG in BCG-naïve Patients With Intermediate and High-risk Non-muscle Invasive Bladder (NMIBC)

Who this might be right for
Bladder CancerBladder Cancer RecurrentNeoplasm Recurrence+3 more
Verity Pharmaceuticals Inc. 540
Testing effectiveness (Phase 2)Looking for participantsNCT05410730
What this trial is testing

SHR-1501 Alone or in Combination With BCG or SHR-1316 in Subjects With NMIBC

Who this might be right for
High-risk NMIBC
Shanghai Hengrui Pharmaceutical Co., Ltd. 150
Large-scale testing (Phase 3)WithdrawnNCT01284205
What this trial is testing

First Line Comparative Study of EN3348 (MCC) vs BCG in NMIBC

Who this might be right for
Bladder Cancer
Bioniche Life Sciences Inc.
Post-approval studies (Phase 4)Study completedNCT02214602
What this trial is testing

Value of Immediate Post-operative Intravesical Epirubicin in Intermediate&High Risk Non Muscle Invasive Bladder Cancer

Who this might be right for
Carcinoma of Urinary Bladder, Superficial
Mansoura University 240
Large-scale testing (Phase 3)UnknownNCT04490993
What this trial is testing

Safety and Efficacy of APL-1202 in Combination With Epirubicin Hydrochloride Versus Epirubicin Hydrochloride Alone in Intermediate and High-risk Chemo-refractory Non-muscle Invasive Bladder Cancer (NMIBC) Patients

Who this might be right for
Non-muscle Invasive Bladder Cancer
Jiangsu Yahong Meditech Co., Ltd aka Asieris 359
Early research (Phase 1)Looking for participantsNCT06108492
What this trial is testing

A Phase I Clinical Study of SHR-2005 Intravesical Instillation in the Treatment of Intermediate and High-risk Non-muscle Invasive Bladder Cancer (NMIBC)

Who this might be right for
Intermediate and High-risk Non-muscle Invasive Bladder Cancer
Shanghai Hengrui Pharmaceutical Co., Ltd. 170
Testing effectiveness (Phase 2)Looking for participantsNCT06388720
What this trial is testing

The Clinical Effectiveness and Safety of Intravesical Mitomycin-C and Gemcitabine Sequential Therapy

Who this might be right for
Bladder Cancer
National Cancer Center, Korea 82
Not applicableUnknownNCT05671900
What this trial is testing

Gemcitabine and Docetaxel Therapy in High-risk BCG-naive Patients With Non-muscle Invasive Bladder Cancer

Who this might be right for
Non-muscle-invasive Bladder Cancer
Clinical Hospital Centre Zagreb 70
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