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Results for “Higher-Risk Myelodysplastic Syndrome”

516 trials

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Showing 20 of 516 results

Testing effectiveness (Phase 2)Study completedNCT04103879
What this trial is testing

US Study of UM171-Expanded CB in Patients With High Risk Leukemia/Myelodysplasia

Who this might be right for
High Risk Hematological MalignancyCord Blood Transplant
ExCellThera inc. 30
Early research (Phase 1)Study completedNCT01300572
What this trial is testing

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Who this might be right for
Chronic Myelomonocytic LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Lymphoblastic Leukemia+3 more
Fred Hutchinson Cancer Center 16
Early research (Phase 1)Ended earlyNCT02641002
What this trial is testing

CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Celgene 28
Testing effectiveness (Phase 2)Ended earlyNCT05835011
What this trial is testing

Oral Decitabine/Cedazuridine in Combination With Magrolimab in Participants With Intermediate- to Very High-Risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic Syndromes
Astex Pharmaceuticals, Inc. 2
Early research (Phase 1)Looking for participantsNCT07573111
What this trial is testing

Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

Who this might be right for
Acute LeukemiaMyelodysplastic Syndrome
Laguna Biotherapeutics, Inc. 12
Testing effectiveness (Phase 2)Study completedNCT00968071
What this trial is testing

Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia and High-risk Myelodysplastic Syndrome

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
M.D. Anderson Cancer Center 71
Testing effectiveness (Phase 2)Study completedNCT00096122
What this trial is testing

Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+20 more
National Cancer Institute (NCI) 95
Early research (Phase 1)Study completedNCT03263637
What this trial is testing

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Who this might be right for
Relapsed or Refractory Haematological Malignancies IncludingAcute Myeloid LeukemiaAcute Lymphocytic Leukemia+8 more
AstraZeneca 44
Testing effectiveness (Phase 2)Study completedNCT00064311
What this trial is testing

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+9 more
National Institutes of Health Clinical Center (CC)
Testing effectiveness (Phase 2)Study completedNCT01168219
What this trial is testing

Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaAdult Acute Megakaryoblastic LeukemiaAdult Acute Monoblastic Leukemia+17 more
National Cancer Institute (NCI) 68
Testing effectiveness (Phase 2)Study completedNCT00656617
What this trial is testing

Phase II Study of Idarubicin, Cytarabine, and Vorinostat With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)
M.D. Anderson Cancer Center 106
Testing effectiveness (Phase 2)Looking for participantsNCT04068597
What this trial is testing

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

Who this might be right for
Haematological MalignancyAcute Myeloid LeukemiaNon Hodgkin Lymphoma+3 more
CellCentric Ltd. 250
Early research (Phase 1)WithdrawnNCT05823480
What this trial is testing

Magrolimab in Combination with Azacitidine After Allogeneic HCTin Treating Patients with High-Risk AML or MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
City of Hope Medical Center
Testing effectiveness (Phase 2)Study completedNCT00778375
What this trial is testing

Clofarabine Plus Low-Dose Cytarabine Induction and Decitabine Consolidation in Frontline Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
M.D. Anderson Cancer Center 122
Testing effectiveness (Phase 2)Study completedNCT00721214
What this trial is testing

5-Azacytidine Prior to Allogeneic Stem Cell Transplant in High Risk Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndrome
Virginia Commonwealth University 16
Early research (Phase 1)Ended earlyNCT00589316
What this trial is testing

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+7 more
Fred Hutchinson Cancer Center
Large-scale testing (Phase 3)Study completedNCT03092674
What this trial is testing

Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeMyelodysplastic Syndrome/Acute Myeloid Leukemia
National Cancer Institute (NCI) 76
Testing effectiveness (Phase 2)Looking for participantsNCT06046313
What this trial is testing

Prolonged Ultra Low-dose Decitabine Plus Venetoclax for Primary Diagnosed Elderly AMLK/MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
First Affiliated Hospital of Zhejiang University 120
Testing effectiveness (Phase 2)Ended earlyNCT04849910
What this trial is testing

Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDS

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Vor Biopharma 67
Testing effectiveness (Phase 2)WithdrawnNCT02765997
What this trial is testing

StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphocytic LeukemiaChronic Myelogenous Leukemia+1 more
Masonic Cancer Center, University of Minnesota
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