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Results for “Higher-risk Myelodysplastic Syndrome”

516 trials

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Showing 20 of 516 results

Not applicableStudy completedNCT00716911
What this trial is testing

Measuring Changes in Blood in Patients at High Risk of Cytomegalovirus Infection After Undergoing Donor Bone Marrow Transplant or Peripheral Blood Stem Cell Transplant

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
City of Hope Medical Center 100
Testing effectiveness (Phase 2)UnknownNCT00885508
What this trial is testing

The Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q

Who this might be right for
Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaAcute Myeloid Leukemia
Groupe Francophone des Myelodysplasies 85
Testing effectiveness (Phase 2)Ended earlyNCT06268574
What this trial is testing

Safety and Efficacy of RVU120 for Treatment of Relapsed/Refractory AML

Who this might be right for
Acute Myeloid Leukemia (AML)High-risk Myelodysplastic Syndrome
Ryvu Therapeutics SA 62
Testing effectiveness (Phase 2)Looking for participantsNCT04068597
What this trial is testing

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

Who this might be right for
Haematological MalignancyAcute Myeloid LeukemiaNon Hodgkin Lymphoma+3 more
CellCentric Ltd. 250
Testing effectiveness (Phase 2)Looking for participantsNCT03589729
What this trial is testing

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

Who this might be right for
Acute Myeloid LeukemiaBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveBlasts 10 Percent or More of Bone Marrow Nucleated Cells+4 more
M.D. Anderson Cancer Center 100
Testing effectiveness (Phase 2)Study completedNCT01289457
What this trial is testing

Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 282
Early research (Phase 1)Ended earlyNCT00725062
What this trial is testing

Donor T Cells in Treating Patients With High-Risk Hematologic Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+2 more
Masonic Cancer Center, University of Minnesota 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT02935361
What this trial is testing

Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes
University of Southern California 33
Testing effectiveness (Phase 2)Ended earlyNCT03946670
What this trial is testing

MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).

Who this might be right for
Myelodysplastic Syndromes
Novartis Pharmaceuticals 127
Testing effectiveness (Phase 2)UnknownNCT01556477
What this trial is testing

The Efficacy of Azacitidine +/- Lenalidomide in High-risk Myelodysplastic Syndrome (MDS)and Acute Myeloid Leukemia (AML) With Del(5q).

Who this might be right for
Myelodysplastic SyndromeAcute Myelogenous Leukemia
Nordic MDS Group 72
Early research (Phase 1)Temporarily pausedNCT03494569
What this trial is testing

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia+5 more
City of Hope Medical Center 36
Testing effectiveness (Phase 2)UnknownNCT01423175
What this trial is testing

ClAraC or FLAMSA Followed by Stem Cell Transplantation to Treat High Risk AML or Advanced MDS

Who this might be right for
Acute Myeloid LeukemiaMDS
Hannover Medical School 60
Testing effectiveness (Phase 2)Study completedNCT03030612
What this trial is testing

ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
OncoVerity, Inc. 38
Testing effectiveness (Phase 2)Study completedNCT00531232
What this trial is testing

A Dose Confirmation Study of Oral Clofarabine for Adult Patients Previously Treated for Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic SyndromesSecondary Acute Myeloid Leukemia (AML)
Genzyme, a Sanofi Company 38
Testing effectiveness (Phase 2)Ended earlyNCT02929498
What this trial is testing

Safety, Clinical Activity, Pharmacokinetics (PK) and Pharmacodynamics Study of GSK2879552, Alone or With Azacitidine, in Subjects With High Risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic SyndromeMyelodysplastic Syndromes
GlaxoSmithKline 7
Testing effectiveness (Phase 2)Study completedNCT00451048
What this trial is testing

Sunitinib in Treating Patients With Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Who this might be right for
Chronic Myelomonocytic Leukemiade Novo Myelodysplastic SyndromesMyelodysplastic Syndromes+1 more
National Cancer Institute (NCI) 10
Not applicableEnded earlyNCT00967525
What this trial is testing

Intraosseous Infusion of Unrelated Cord Blood Grafts

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+1 more
Emory University 5
Testing effectiveness (Phase 2)Study completedNCT01085838
What this trial is testing

Erlotinib in Higher Risk Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndrome
Groupe Francophone des Myelodysplasies 30
Early research (Phase 1)Looking for participantsNCT05292664
What this trial is testing

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Who this might be right for
Myelodysplastic Syndromes, de NovoMyelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously Treated+8 more
Andrew E. Place, MD 30
Testing effectiveness (Phase 2)Study completedNCT00569010
What this trial is testing

Phase I/II Study of 5-Azacytidine With Ara-C in Patients With Relapsed/Refractory Acute Myelogenous Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic SyndromeLeukemia
M.D. Anderson Cancer Center 36
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