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Results for “Histiocytoses Erdheim-chester Disease”

24 trials

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Showing 20 of 24 results

Testing effectiveness (Phase 2)Looking for participantsNCT04079179
What this trial is testing

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Who this might be right for
Langerhan's Cell HistiocytosisJuvenile XanthogranulomaErdheim-Chester Disease+4 more
Carl Allen 90
Not applicableUnknownNCT06332183
What this trial is testing

GWAS and EWAS in Patients With Erdheim-Chester Disease

Who this might be right for
Erdheim-Chester Disease
Augusto Vaglio 300
Not applicableLooking for participantsNCT03990428
What this trial is testing

Supportive Care Needs of Caregivers of People With Erdheim-Chester Disease and Other Histiocytic Diseases

Who this might be right for
Supportive Care Needs of Caregivers
Memorial Sloan Kettering Cancer Center 250
Early research (Phase 1)Active Not RecruitingNCT01552434
What this trial is testing

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

Who this might be right for
Advanced Malignant NeoplasmCastleman DiseaseDigestive System Carcinoma+36 more
M.D. Anderson Cancer Center 155
Not applicableUnknownNCT02089724
What this trial is testing

Long-term Outcome After Vemurafenib / BRAF Inhibitors Interruption in Erdheim-chester Disease

Who this might be right for
Erdheim-Chester Disease
Groupe Hospitalier Pitie-Salpetriere 20
Not applicableLooking for participantsNCT05915208
What this trial is testing

Histiocytic Disorder Follow-up Study

Who this might be right for
HistiocytosisLangerhans Cell HistiocytosisErdheim-Chester Disease+3 more
University of Alabama at Birmingham 6,000
Not applicableLooking for participantsNCT03329274
What this trial is testing

Registry for Patients With Erdheim-Chester Disease and Other Histiocytoses

Who this might be right for
Erdheim-Chester Disease
Memorial Sloan Kettering Cancer Center 500
Very early researchLooking for participantsNCT05093335
What this trial is testing

In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

Who this might be right for
Non-Hodgkin LymphomaMultiple MyelomaHistiocytic Neoplasms+2 more
Memorial Sloan Kettering Cancer Center 30
Testing effectiveness (Phase 2)Study completedNCT02281760
What this trial is testing

Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease

Who this might be right for
BRAF V600E Mutation
National Human Genome Research Institute (NHGRI) 9
Not applicableLooking for participantsNCT02285582
What this trial is testing

International Rare Histiocytic Disorders Registry (IRHDR)

Who this might be right for
Rare Histiocytic Disorders (RHDs)Erdheim-Chester Disease (ECD)Rosai-Dorfman Disease (RDD)+7 more
The Hospital for Sick Children 400
Testing effectiveness (Phase 2)Ended earlyNCT01727206
What this trial is testing

Pilot Study of Tocilizumab in Patients With Erdheim-Chester Disease

Who this might be right for
Erdheim-Chester Disease
Ospedale San Raffaele 3
Large-scale testing (Phase 3)Not Yet RecruitingNCT07440290
What this trial is testing

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+16 more
Cancer Research UK 30
Not applicableStudy completedNCT01417520
What this trial is testing

Clinical and Pathophysiological Investigations Into Erdheim Chester Disease

Who this might be right for
MyelofibrosisGaucher DiseasePulmonary Fibrosis+2 more
National Human Genome Research Institute (NHGRI) 88
Not applicableActive Not RecruitingNCT03127709
What this trial is testing

Memory, Thinking, and Brain Imaging in Adults With Histiocytosis

Who this might be right for
Histiocytosis
Memorial Sloan Kettering Cancer Center 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT02523040
What this trial is testing

Lenalidomide for Adult Histiocyte Disorders

Who this might be right for
Langerhans Cell Histiocytosis (LCH)Histiocytoses Erdheim-chester DiseaseHistiocytic Sarcoma (HS)
Dana-Farber Cancer Institute 12
Testing effectiveness (Phase 2)Ended earlyNCT04198818
What this trial is testing

Evaluate the Safety, Tolerability and Pharmacokinetics of HH2710 in Patient With Advanced Tumors

Who this might be right for
Advanced TumorsMelanomaNon-Small-Cell Lung Cancer+2 more
Haihe Biopharma Co., Ltd. 37
Not applicableStudy completedNCT02608619
What this trial is testing

Uptake and Biodistribution of 18F-fluorocholine in Histiocytic Disorders by PET Imaging and Biopsy Measurement

Who this might be right for
Erdheim-Chester DiseaseLangerhans Cell HistiocytosisHistiocytic Disorders
Memorial Sloan Kettering Cancer Center 3
Testing effectiveness (Phase 2)WithdrawnNCT03794297
What this trial is testing

Dabrafenib and Trametinib in Treating Patients With Erdheim Chester Disease With BRAF V600 Mutations

Who this might be right for
Erdheim-Chester Disease
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)UnknownNCT05092815
What this trial is testing

The Efficacy and Safety of HLX208 in Adult Langerhans Cell Histiocytosis (LCH) and Erdheim-Chester Disease (ECD) With BRAF V600E Mutation

Who this might be right for
Langerhans Cell HistiocytosisErdheim-Chester DiseaseLCH+1 more
Shanghai Henlius Biotech 25
Large-scale testing (Phase 3)Looking for participantsNCT05768178
What this trial is testing

DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.

Who this might be right for
Haematological MalignancyMelanomaThyroid Cancer, Papillary+9 more
Cancer Research UK 30
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