Not applicableUnknownNCT06332183What this trial is testingGWAS and EWAS in Patients With Erdheim-Chester DiseaseWho this might be right forErdheim-Chester Disease Augusto Vaglio 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT02523040What this trial is testingLenalidomide for Adult Histiocyte DisordersWho this might be right forLangerhans Cell Histiocytosis (LCH)Histiocytoses Erdheim-chester DiseaseHistiocytic Sarcoma (HS) Dana-Farber Cancer Institute 12
Testing effectiveness (Phase 2)Ended earlyNCT01727206What this trial is testingPilot Study of Tocilizumab in Patients With Erdheim-Chester DiseaseWho this might be right forErdheim-Chester Disease Ospedale San Raffaele 3
Not applicableLooking for participantsNCT03329274What this trial is testingRegistry for Patients With Erdheim-Chester Disease and Other HistiocytosesWho this might be right forErdheim-Chester Disease Memorial Sloan Kettering Cancer Center 500
Not applicableUnknownNCT02089724What this trial is testingLong-term Outcome After Vemurafenib / BRAF Inhibitors Interruption in Erdheim-chester DiseaseWho this might be right forErdheim-Chester Disease Groupe Hospitalier Pitie-Salpetriere 20
Not applicableUnknownNCT06317246What this trial is testingSubtypes and Prognostic Factors in Erdheim-Chester DiseaseWho this might be right forErdheim-Chester Disease Meyer Children's Hospital IRCCS 70
Large-scale testing (Phase 3)Looking for participantsNCT05768178What this trial is testingDETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.Who this might be right forHaematological MalignancyMelanomaThyroid Cancer, Papillary+9 more Cancer Research UK 30
Not applicableLooking for participantsNCT07454343What this trial is testingECD-Score: a Study on Erdheim-Chester DiseaseWho this might be right forErdheim-Chester Disease (ECD) Meyer Children's Hospital IRCCS 1,000
Not applicableActive Not RecruitingNCT03127709What this trial is testingMemory, Thinking, and Brain Imaging in Adults With HistiocytosisWho this might be right forHistiocytosis Memorial Sloan Kettering Cancer Center 13
Testing effectiveness (Phase 2)WithdrawnNCT03794297What this trial is testingDabrafenib and Trametinib in Treating Patients With Erdheim Chester Disease With BRAF V600 MutationsWho this might be right forErdheim-Chester Disease National Cancer Institute (NCI)
Testing effectiveness (Phase 2)UnknownNCT05092815What this trial is testingThe Efficacy and Safety of HLX208 in Adult Langerhans Cell Histiocytosis (LCH) and Erdheim-Chester Disease (ECD) With BRAF V600E MutationWho this might be right forLangerhans Cell HistiocytosisErdheim-Chester DiseaseLCH+1 more Shanghai Henlius Biotech 25
Testing effectiveness (Phase 2)Ended earlyNCT04198818What this trial is testingEvaluate the Safety, Tolerability and Pharmacokinetics of HH2710 in Patient With Advanced TumorsWho this might be right forAdvanced TumorsMelanomaNon-Small-Cell Lung Cancer+2 more Haihe Biopharma Co., Ltd. 37
Not applicableStudy completedNCT02608619What this trial is testingUptake and Biodistribution of 18F-fluorocholine in Histiocytic Disorders by PET Imaging and Biopsy MeasurementWho this might be right forErdheim-Chester DiseaseLangerhans Cell HistiocytosisHistiocytic Disorders Memorial Sloan Kettering Cancer Center 3
Very early researchLooking for participantsNCT05093335What this trial is testingIn-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PETWho this might be right forNon-Hodgkin LymphomaMultiple MyelomaHistiocytic Neoplasms+2 more Memorial Sloan Kettering Cancer Center 30
Large-scale testing (Phase 3)Looking for participantsNCT07440290What this trial is testingDETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.Who this might be right forHaematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+17 more Cancer Research UK 30
Not applicableLooking for participantsNCT03990428What this trial is testingSupportive Care Needs of Caregivers of People With Erdheim-Chester Disease and Other Histiocytic DiseasesWho this might be right forSupportive Care Needs of Caregivers Memorial Sloan Kettering Cancer Center 250
Testing effectiveness (Phase 2)Study completedNCT02281760What this trial is testingDabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester DiseaseWho this might be right forBRAF V600E Mutation National Human Genome Research Institute (NHGRI) 9
Testing effectiveness (Phase 2)Looking for participantsNCT04079179What this trial is testingCobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic DisordersWho this might be right forLangerhan's Cell HistiocytosisJuvenile XanthogranulomaErdheim-Chester Disease+4 more Carl Allen 90
Not applicableLooking for participantsNCT02285582What this trial is testingInternational Rare Histiocytic Disorders Registry (IRHDR)Who this might be right forRare Histiocytic Disorders (RHDs)Erdheim-Chester Disease (ECD)Rosai-Dorfman Disease (RDD)+7 more The Hospital for Sick Children 400
Not applicableWithdrawnNCT02298634What this trial is testingBiomarker for Farber Disease (BioFarber)Who this might be right forFarber's LipogranulomatosisCeramidase DeficiencyHepatomegaly+1 more CENTOGENE GmbH Rostock