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Results for “Homologous Recombination Deficiency”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Ended earlyNCT00448266
What this trial is testing

Intensified IAA With PBPC Support in Breast Tumors With Evidence of a HRD

Who this might be right for
Breast Cancer
The Netherlands Cancer Institute 12
Testing effectiveness (Phase 2)WithdrawnNCT03032614
What this trial is testing

Combination of Carboplatin, Eribulin and Veliparib in Stage IV Cancer Patients

Who this might be right for
Breast Cancer Stage IVOvarian CancerBRCA1 Mutation+1 more
The University of Texas Health Science Center at San Antonio
Testing effectiveness (Phase 2)Ended earlyNCT05126433
What this trial is testing

Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorUrothelial Cancer+2 more
Jazz Pharmaceuticals 47
Testing effectiveness (Phase 2)Study completedNCT03377556
What this trial is testing

Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
ATM Gene MutationATR Gene MutationBARD1 Gene Mutation+18 more
SWOG Cancer Research Network 51
Testing effectiveness (Phase 2)Looking for participantsNCT06525298
What this trial is testing

EIS-12656 as Single Agent and in Combination in Patients With Specified Solid Tumors

Who this might be right for
Advanced Solid TumorHomologous Recombination DeficiencyHRR Deficiency
Eisbach Bio GmbH 144
Large-scale testing (Phase 3)Study completedNCT02855944
What this trial is testing

ARIEL4: A Study of Rucaparib Versus Chemotherapy BRCA Mutant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients

Who this might be right for
Ovarian CancerEpithelial Ovarian CancerFallopian Tube Cancer+1 more
pharmaand GmbH 349
Large-scale testing (Phase 3)Not Yet RecruitingNCT07694427
What this trial is testing

Mo-Rez in First- Line (1L) Maintenance Treatment of Non-Homologous Recombination Deficient Ovarian Cancer (Non-HRd OC) [BEHOLD-Ovarian03]

Who this might be right for
Ovarian Neoplasms
GlaxoSmithKline 720
Early research (Phase 1)Study completedNCT02418624
What this trial is testing

Phase I of Carboplatin-Olaparib Followed by Olaparib Monotherapy in Advanced Cancer

Who this might be right for
Breast CancerOvarian CancerAdvanced Cancer
The Netherlands Cancer Institute 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT05033756
What this trial is testing

Comprehensive Analysis of Predictors of the Treatment With Pembrolizumab and Olaparib in Patients With Unresectable or Metastatic HER2 Negative Breast Cancer and a Deleterious Germline Mutation or a Homologous Recombination Deficiency (COMPRENDO

Who this might be right for
Malignant Neoplasm of BreastBreast Cancer
Institut fuer Frauengesundheit 11
Testing effectiveness (Phase 2)Study completedNCT06433219
What this trial is testing

Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)

Who this might be right for
Ovarian Cancer
EMD Serono Research & Development Institute, Inc. 63
Testing effectiveness (Phase 2)Looking for participantsNCT03522064
What this trial is testing

Bipolar Androgen Therapy + Carboplatin in mCRPC

Who this might be right for
Castration-resistant Prostate CancerHomologous Recombination Deficiency
St Vincent's Hospital, Sydney 30
Early research (Phase 1)Looking for participantsNCT06666270
What this trial is testing

Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid CancerMetastatic Solid TumorOvarian Cancer+4 more
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd 30
Testing effectiveness (Phase 2)Study completedNCT04508803
What this trial is testing

Combination of HX008 And Niraparib in GErm-line-mutAted Metastatic Breast Cancer

Who this might be right for
Treatment Efficacy
Fudan University 37
Early research (Phase 1)Looking for participantsNCT04890613
What this trial is testing

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

Who this might be right for
Advanced Solid Tumor
Senhwa Biosciences, Inc. 52
Not applicableLooking for participantsNCT06827353
What this trial is testing

Niraparib Versus Bevacizumab as Maintenance Therapy in Patients With de Novo Ovarian Cancer Without Homologous Recombination Deficiency

Who this might be right for
Ovarian Carcinoma
Centre Hospitalier Universitaire de Nīmes 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT04666740
What this trial is testing

Pembrolizumab and Olaparib for People With Metastatic Pancreatic Ductal Adenocarcinoma and Homologous Recombination Deficiency or Exceptional Treatment Response to Platinum-Based Therapy

Who this might be right for
Metastatic Pancreatic Ductal AdenocarcinomaHomologous Recombination Deficiency (HRD)
Memorial Sloan Kettering Cancer Center 63
Large-scale testing (Phase 3)Looking for participantsNCT07472140
What this trial is testing

PARP (Poly (ADP-ribose) Polymerase) Inhibitor With or Without Angiogenesis Inhibitor in Homologous Recombination Deficient Primary Ovarian Cancer, Fallopian-Tube Cancer, or Primary Peritoneal Cancer

Who this might be right for
Ovarian CancerFallopian Tube CancersPrimary Peritoneal Cancer
N.N. Alexandrov National Cancer Centre 120
Testing effectiveness (Phase 2)UnknownNCT05461690
What this trial is testing

Phase II Study of Niraparib in Metastatic TNBC Patients With Homologous Recombination Deficiency

Who this might be right for
Homologous Recombination DeficiencyTriple Negative Breast Cancer
Zhejiang Cancer Hospital 50
Testing effectiveness (Phase 2)UnknownNCT04556071
What this trial is testing

Efficacy and Safety of Niraparib Combined With Bevacizumab in Platinum Refractory/Resistant Recurrent Ovarian Cancer

Who this might be right for
Ovarian NeoplasmsFallopian Tube NeoplasmsEndocrine Gland Neoplasms+21 more
Xiaoxiang Chen 32
Not applicableActive Not RecruitingNCT07303218
What this trial is testing

The HER Project: HRD in EGFR-mutated NSCLC

Who this might be right for
EGFRNon Small Cell Lung CancerHomologous Recombination Deficiency+1 more
IRCCS San Raffaele 100
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