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Results for “Homozygous F508del Mutation”

Showing 7 of 0 results

Testing effectiveness (Phase 2)Study completedNCT02730208
What this trial is testing

Evaluate the Effect of VX-661 in Combination With Ivacaftor on Chest Imaging Endpoints in Subjects With Cystic Fibrosis, Homozygous for the F508del CFTR Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 41
Large-scale testing (Phase 3)Study completedNCT02953314
What this trial is testing

Evaluate the Pharmacokinetics, Safety, and Tolerability of VX-661/Ivacaftor in Pediatric Subjects With Cystic Fibrosis (CF)

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 83
Testing effectiveness (Phase 2)Study completedNCT02070744
What this trial is testing

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 40
Post-approval studies (Phase 4)Study completedNCT02875366
What this trial is testing

The Effects of Lumacaftor/Ivacaftor (LUM/IVA) on Exercise Tolerance in Subjects With Cystic Fibrosis (CF), Homozygous for the F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 70
Testing effectiveness (Phase 2)Study completedNCT03969888
What this trial is testing

ABBV-3067 Alone and in Combination With ABBV-2222

Who this might be right for
Cystic Fibrosis
AbbVie 78
Testing effectiveness (Phase 2)Study completedNCT07108153
What this trial is testing

Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta

Who this might be right for
Cystic Fibrosis (CF)
Sionna Therapeutics Inc. 15
Large-scale testing (Phase 3)Study completedNCT02390219
What this trial is testing

Study to Evaluate Lumacaftor and Ivacaftor Combination Therapy in Subjects 12 Years and Older With Advanced Lung Disease

Who this might be right for
Cystic FibrosisAdvanced Lung Disease
Vertex Pharmaceuticals Incorporated 46

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